Olena Mandrik

MSc Maastricht (the Netherlands), PhD Rotterdam (the Netherlands)

School of Medicine and Population Health

Research Fellow

o.mandrik@sheffield.ac.uk
+44 114 222 6392
Regent Court (ScHARR)

Full contact details

Olena Mandrik
School of Medicine and Population Health
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
Profile

I joined the Health Economics and Decision Science (HEDS) group in October 2018 as a modeller, following a postdoctoral fellowship at the International Agency for Research on Cancer (IARC) of the World Health Organization, and the completion of a PhD at the Erasmus University Rotterdam, School of Health Policy and Management (2015).

My journey into academia followed a seven-year career in the pharmaceutical industry, where I held leadership positions at several global companies, including Janssen-Cilag, Merck, and Sanofi.

At HEDS, I specialise in public health modelling, with a particular focus on the evaluation of prevention and early detection programmes. My areas of interest include cancer, genetic testing, and the exploration of health inequalities. Throughout my research career, I have contributed to the development of several key methodological documents, including leading the ISPOR Task Force on Critical Appraisal of Systematic Reviews With Costs and Cost-Effectiveness Outcomes. I have also contributed to major international evidence synthesis initiatives, such as the IARC Handbooks of Cancer Prevention, Volume 19 on Oral Cancer Prevention.

Currently, I serve as co-Director of the SENSS Evidence Synthesis Group of SCHARR, funded by the NIHR. In this role, I support work aligned with the objectives of the UK National Screening Committee and the NIHR.

Research interests
  • Decision modelling for health economic evaluations
  • Complex public health decision problems
  • Screening, early detection, and diagnostics
  • Inequality and equity analysis
Publications

Show: Featured publications All publications

Journal articles

  • Chanakira EZ, Thomas CV, Balen J & Mandrik O (2024) . Systematic Reviews, 13(1).
  • Mandrik O, Hahn AI, Catto JWF, Zauber AG, Cumberbatch M & Chilcott J (2023) . PharmacoEconomics, 41(6), 633-650.
  • Thomas C, Mandrik O & Whyte S (2022) . Preventive Medicine, 162.
  • Mandrik O, Chilcott J & Thomas C (2022) . Preventive Medicine, 160.
  • Mandrik O, Thomas C, Whyte S & Chilcott J (2022) . PharmacoEconomics, 40(4), 359-366.
  • Mandrik O, Severens JL, Bardach A, Ghabri S, Hamel C, Mathes T, Vale L, Wisløff T & Goldhaber-Fiebert JD (2021) . Value in Health, 24(4), 463-472.

All publications

Journal articles

  • Mandrik O, Whyte S, Kunst N, Rayner A, Harden M, Dias S, Payne K, Palmer S & Soares MO (2025) . Medical Decision Making, 45(8), 1013-1024.
  • Thomas C, Mandrik O, Chilcott J, Crooks C, Humes D, Hamilton W & Rees C (2025) . BMJ Public Health, 3(1).
  • Masuku SD, Mandrik O, Mdege ND, Mishra G, Muwonge R, Meyer-Rath G, Lince-Deroche N & Brennan A (2025) . Value in Health Regional Issues, 49.
  • Villain P, Downham L, Le Bonniec A, Bauquier C, Mandrik O, Nadarzynski T, Donelle L, Murillo R, Tolma EL, Johnson S , Soler-Michel P et al (2025) . Journal of Medical Internet Research, 27.
  • Mandrik O, Thomas C, Akpan E, Catto JWF & Chilcott J (2025) . PharmacoEconomics, 43(4), 441-452.
  • Rajgor A, Hurley R, Douglas CM, Paterson C, Moor J, Lester S, Sionis S, Davies K, O'Hara J, Inman G , Jones T et al (2025) . Clinical Otolaryngology, 50(2), 344-351.
  • Hill H, Roadevin C, Duffy S, Mandrik O & Brentnall A (2024) . JAMA Network Open, 7(9).
  • Chanakira EZ, Thomas CV, Balen J & Mandrik O (2024) . Systematic Reviews, 13(1).
  • Mandrik O, Thomas C & Chilcott J (2024) Development of the Microsimulation Model in Cancers of Bladder and Kidney (MiMiC-BlaKy). HEDS Discussion Paper Series(24.03).
  • Catto JWF, North B, Goff M, Carter A, Sleeth M, Mandrik O, Chilcott J, Sasieni P & Cumberbatch MGK (2023) . BMJ Open, 13(9).
  • Mandrik O, Hahn AI, Catto JWF, Zauber AG, Cumberbatch M & Chilcott J (2023) . PharmacoEconomics, 41(6), 633-650.
  • Catto JWF, Mandrik O, Quayle LA, Hussain SA, McGrath J, Cresswell J, Birtle AJ, Jones RJ, Mariappan P, Makaroff LE , Knight A et al (2023) . BJU International, 131(6), 734-744.
  • Mandrik O, Roitberg F, Lauby-Secretan B, Parak U, Ramadas K, Varenne B, Sankaranarayanan R & Carvalho AL (2023) . Journal of Cancer Policy, 35.
  • Bouvard V, Nethan ST, Singh D, Warnakulasuriya S, Mehrotra R, Chaturvedi AK, Chen TH-H, Ayo-Yusuf OA, Gupta PC, Kerr AR , Tilakaratne WM et al (2022) . New England Journal of Medicine.
  • Parak U, Lopes Carvalho A, Roitberg F & Mandrik O (2022) . Preventive Medicine Reports, 30, 101987-101987.
  • Lourenção M, Simões Correa Galendi J, Galvão HDCR, Antoniazzi AP, Grasel RS, Carvalho AL, Mauad EC, Oliveira JHCD, Reis RM, Mandrik O & Palmero EI (2022) . Frontiers in Oncology, 12.
  • Thomas C, Mandrik O & Whyte S (2022) . Preventive Medicine, 162.
  • Mandrik O, Chilcott J & Thomas C (2022) . Preventive Medicine, 160.
  • Mandrik O, Fotheringham J, Ren S, Tice JA, Chapman RH, Stevenson MD, Pearson SD, Herron-Smith S, Agboola F & Thokala P (2022) . Clinical Journal of the American Society of Nephrology, 17(3), 385-394.
  • Mandrik O, Thomas C, Whyte S & Chilcott J (2022) . PharmacoEconomics, 40(4), 359-366.
  • Tice JA, Mandrik O, Thokala P, Fotheringham J & Pearson SD (2021) . Journal of Managed Care & Specialty Pharmacy, 27(10), 1495-1499.
  • Thomas C, Mandrik O, Saunders CL, Thompson D, Whyte S, Griffin S & Usher-Smith JA (2021) . Cancer Prevention Research, 14(8), 811-822.
  • Mandrik O, Tolma E, Zielonke N, Meheus F, Ordóñez-Reyes C, Severens H & Murillo R (2021) . Journal of Medical Screening, 28(2), 70-79.
  • Mandrik O, Severens JL, Bardach A, Ghabri S, Hamel C, Mathes T, Vale L, Wisløff T & Goldhaber-Fiebert JD (2021) . Value in Health, 24(4), 463-472.
  • Thomas C, Mandrik O, Whyte S, Saunders CL, Griffin SJ & Usher-Smith JA (2021) . Cancer Reports, 4(4).
  • Escriva-Boulley G, Mandrik O, Préau M, Herrero R & Villain P (2021) . Preventive Medicine, 143.
  • Daubner-Bendes R, Kovács S, Niewada M, Huic M, Drummond M, Ciani O, Blankart CR, Mandrik O & Kaló Z (2021) . Frontiers in Public Health, 8.
  • Isah AUJ, Ekwunife OI, Ejie IL & Mandrik O (2020) . PLoS ONE, 15(8).
  • Mandrik O, Ekwunife O, Meheus F, Severens JL, Lhachimi S, Uyl-de Groot CA & Murillo R (2019) . Cancer Medicine, 8(18), 7846-7858.
  • Mandrik O, Yaumenenka A, Herrero R & Jonker M (2019) . PLoS ONE, 1.
  • Mandrik O, Zielonke N, Meheus F, Severens H, Guha N, Herrero R & Murillo R (2019) . International Journal of Cancer, 145(4), 994-1006.
  • Mandrik O, Ekwunife OI, Zielonke N, Meheus F, Severens JL, Lhachimi SK & Murillo R (2017) . Systematic Reviews, 6(1).
  • Mandrik O, Knies S, Kalo Z & Severens JL (2015) . International Journal of Technology Assessment in Health Care, 31(6), 434-441.
  • Mandrik O, Knies S, Golubovska О, Duda O, Dudar L, Fedorchenko S, Zaliska О & Severens JLH (2015) . Open Medicine, 10(1).
  • Mandrik O, Knies S, Kaló Z & Severens JL (2014) . Value in Health, 17(7), A443-A444.
  • Mandrik O, Corro Ramos I, Zalis’ka O, Gaisenko A & Severens JL (2013) . Value in Health Regional Issues, 2(2), 205-209.
  • Zalis'ka O & Mandrik O (2010) . Value in Health, 13(7), A400-A400.
  • Lin L, Severens JL & Mandrik O () . PLoS ONE, 14(7).
  • Mandrik O, Corro Ramos I, Knies S, Al M & Severens JH () . Cancer Management and Research, 279-279.
  • Mandrik O, Knies S & Severens JH () . ClinicoEconomics and Outcomes Research, 347-347.
  • Mandrik O, Mankovsky B, Doroshenko O, Pan'kiv V, Kravchun N, Vlasenko M, Hulchiy M, Baljuk M, Komisarenko Y, Martsynik E , Sokolova L et al () . Journal of Multidisciplinary Healthcare, 249-249.

Conference proceedings

  • Harnan S, Gittus M, Falzon L, Durkie M, Mandrik O, Ong A & Fotheringham J (2025) . Clinical Kidney Journal, Vol. 18(7)
  • Villain P, Downham L, Le Bonniec A, Bauquier C, Mandrik O, Nadarzynski T, Donelle L, Johnson S, Murillo R, Soler-Michel P , Tolma EL et al (2024) Effect of online interactive decision tools on breast cancer screening decisions: A systematic review and meta-analysis. INTERNATIONAL JOURNAL OF CANCER, Vol. 155 (pp 24-24)
  • Mandrik O, Zalis'ka O & Severens J (2012) . Value in Health, Vol. 15(7) (pp A428-A428)
  • Mandrik O, Zalis'ka O & Severens JL (2012) . Value in Health, Vol. 15(4) (pp A221-A221)
  • Pariy V, Stepanenko A, Mandrik O & Zalis'ka O (2012) . Value in Health, Vol. 15(4) (pp A32-A32)
  • Mandrik O, Severens JL, Zalis'ka O, Doroshenko O, Maynych Y & Tolubaiev V (2012) . Value in Health, Vol. 15(4) (pp A28-A28)
  • Mandrik O, Zalis'ka O & Severens JL (2011) . Value in Health, Vol. 14(7) (pp A444-A444)
  • Mandrik O & Zalis'ka O (2011) . Value in Health, Vol. 14(3) (pp A163-A163)

Reports

  • Thomas C, Mandrik O & Whyte S (2020) Development of the Microsimulation Model in Cancer of the Bowel (MiMiC-Bowel), an Individual Patient Simulation Model for Investigation of the Cost-effectiveness of Personalised Screening and Surveillance Strategies

Datasets

  • Mandrik O, Yaumenenka A, Herrero R & Jonker MF .

Preprints

  • Mandrik O, Whyte S, Kunst N, Rayner A, Harden M, Dias S, Payne K, Palmer S & Soares M (2025) , arXiv.
  • Villain P, Downham L, Le Bonniec A, Bauquier C, Mandrik O, Nadarzynski T, Donelle L, Murillo R, Tolma EL, Johnson S , Soler-Michel P et al (2024) , JMIR Publications Inc..
  • Mandrik O, Thomas C, Strong M & Whyte S (2021) Calibration and Validation of the Microsimulation Model in Cancer of the Bowel (MiMiC-Bowel), an Individual Patient Simulation Model for Investigation of the Cost-effectiveness of Personalised Screening and Surveillance Strategies.
Teaching interests

I supervise MSc and PhD students and welcome inquiries from prospective research students interested in public health decision modelling.