Lydia Castelli

School of Medicine and Population Health

Senior Experimental Officer

l.m.castelli@sheffield.ac.uk
+44 114 2159110
Sheffield Institute for Translational Neuroscience (SITraN)

Full contact details

Lydia Castelli
School of Medicine and Population Health
Sheffield Institute for Translational Neuroscience (SITraN)
385a Glossop Road
Sheffield
S10 2HQ
Publications

Journal articles

  • Webster CP, Hall B, Crossley OM, Dauletalina D, King M, Lin Y-H, Castelli LM, Yang Z-L, Coldicott I, Kyrgiou-Balli E , Higginbottom A et al (2025) . Life Science Alliance, 8(2).
  • Burrows DJ, McGown A, Abduljabbar O, Castelli LM, Shaw PJ, Hautbergue GM & Ramesh TM (2024) . Annals of Neurology, 96(6), 1058-1069.
  • Mihaylov SR, Castelli LM, Lin Y-H, Gül A, Soni N, Hastings C, Flynn HR, Păun O, Dickman MJ, Snijders AP , Goldstone R et al (2023) . Nature Communications, 14.
  • Kershaw CJ, Nelson MG, Castelli LM, Jennings MD, Lui J, Talavera D, Grant CM, Pavitt GD, Hubbard SJ & Ashe MP (2023) . Journal of Biological Chemistry, 299(10), 105195-105195.
  • Allen SP, Al Sultan A, Kabucho Kibirige E, Tonkiss E, Hamer KJ, Castelli LM, Lin Y-H, Roscoe S, Stefanidis N, Mead RJ , Highley JR et al (2023) . Frontiers in Aging Neuroscience, 15.
  • Castelli LM, Lin Y-H, Sanchez-Martinez A, Gül A, Imran KM, Higginbottom A, Márkus NM, Upadhyay SK, Martins AW, Cooper-Knock J , Montmasson C et al (2023) . Science Translational Medicine, 15(685).
  • Moll T, Odon V, Harvey C, Collins MO, Peden A, Franklin J, Graves E, Marshall JNG, dos Santos Souza C, Zhang S , Castelli L et al (2023) . Life Science Alliance, 6(1).
  • Cooper‐Knock J, Julian TH, Feneberg E, Highley JR, Sidra M, Turner MR, Talbot K, Ansorge O, Allen SP, Moll T , Shelkovnikova T et al (2023) . Brain Pathology, 33(1).
  • Bauer CS, Webster CP, Shaw AC, Kok JR, Castelli LM, Lin Y-H, Smith EF, Illanes-Álvarez F, Higginbottom A, Shaw PJ , Azzouz M et al (2022) . Frontiers in Cellular Neuroscience, 16.
  • Castelli LM, Benson BC, Huang W-P, Lin Y-H & Hautbergue GM (2022) . Frontiers in Genetics, 13.
  • Castelli LM, Cutillo L, Souza CDS, Sanchez-Martinez A, Granata I, Lin Y-H, Myszczynska MA, Heath PR, Livesey MR, Ning K , Azzouz M et al (2021) . Molecular Neurodegeneration, 16(1).
  • Nwokoye EC, AlNaseem E, Crawford RA, Castelli LM, Jennings MD, Kershaw CJ & Pavitt GD (2021) . Scientific Reports, 11(1).
  • Castelli LM, Huang W-P, Lin Y-H, Chang K-Y & Hautbergue GM (2021) . Biochemical Society Transactions, 49(2), 775-792.
  • Gatto N, Dos Santos Souza C, Shaw AC, Bell SM, Myszczynska MA, Powers S, Meyer K, Castelli LM, Karyka E, Mortiboys H , Azzouz M et al (2021) . Aging Cell, 20(1).
  • Allen S, Hall B, Castelli L, Francis L, Woof R, Siskos A, Kouloura E, Gray E, Thompson A, Talbot K , Higginbottom A et al (2019) . Brain, 142(3), 586-605.
  • Cooper-Knock J, Moll T, Ramesh T, Castelli L, Beer A, Robins H, Fox I, Niedermoser I, Van Damme P, Moisse M , Robberecht W et al (2019) . Cell Reports, 26(9), 2298-2306.e5.
  • Varcianna AE, Myszczynska MA, Castelli LM, O'Neill B, Kim Y, Talbot J, Nyberg S, Nymali I, Heath PR, Stopford MJ , Hautbergue GM et al (2019) . EBioMedicine, 40, 626-635.
  • Shaw MP, Higginbottom A, McGown A, Castelli LM, James E, Hautbergue GM, Shaw PJ & Ramesh TM (2018) . Acta Neuropathologica Communications, 6(1).
  • Morgan SV, Garwood CJ, Jennings L, Simpson JE, Castelli LM, Heath PR, Mihaylov SR, Vazquez Villasenor I, Minshull TC, Ince PG , Dickman MJ et al (2018) . European Journal of Neuroscience, 47(12), 1444-1456.
  • Talavera D, Kershaw CJ, Costello JL, Castelli LM, Rowe W, Sims PFG, Ashe MP, Grant CM, Pavitt GD & Hubbard SJ (2018) . Scientific Reports, 8(1).
  • Castelli LM, Lin YH, Ferraiuolo L, Sanchez-Martinez A, Ning KE, Azzouz M, Whitworth A, Shaw PJ & Hautbergue GM (2018) . Therapeutic Targets for Neurological Diseases, 4.
  • Chandran JS, Sharp PS, Karyka E, Aves-Cruzeiro JMDC, Coldicott I, Castelli L, Hautbergue G, Collins MO & Azzouz M (2017) . Scientific Reports, 7.
  • Costello JL, Kershaw CJ, Castelli LM, Talavera D, Rowe W, Sims PFG, Ashe MP, Grant CM, Hubbard SJ & Pavitt GD (2017) . Genome Biology , 18.
  • Egbe NE, Dornelles TO, Paget CM, Castelli LM & Ashe MP (2017) . Microbial Cell, 4(9), 294-304.
  • Hautbergue GM, Castelli LM, Ferraiuolo L, Sanchez-Martinez A, Cooper-Knock J, Higginbottom A, Lin YH, Bauer CS, Dodd JE, Myszczynska MA , Alam SM et al (2017) . Nature Communications, 8.
  • Kershaw CJ, Costello JL, Talavera D, Rowe W, Castelli LM, Sims PFG, Grant CM, Ashe MP, Hubbard SJ & Pavitt GD (2015) . Scientific Reports, 5.
  • Castelli LM, Talavera D, Kershaw CJ, Mohammad-Qureshi SS, Costello JL, Rowe W, Sims PFG, Grant CM, Hubbard SJ, Ashe MP & Pavitt GD (2015) . PLOS Genetics, 11(5).
  • Kershaw CJ, Costello JL, Castelli LM, Talavera D, Rowe W, Sims PFG, Ashe MP, Hubbard SJ, Pavitt GD & Grant CM (2015) . PLoS Genetics, 11(1).
  • Costello J, Castelli LM, Rowe W, Kershaw CJ, Talavera D, Mohammad-Qureshi SS, Sims PFG, Grant CM, Pavitt GD, Hubbard SJ & Ashe MP (2015) . Genome Biology, 16.
  • Lui J, Castelli LM, Pizzinga M, Simpson CE, Hoyle NP, Bailey KL, Campbell SG & Ashe MP (2014) . Cell Reports, 9(3), 944-954.
  • Rowe W, Kershaw CJ, Castelli LM, Costello JL, Ashe MP, Grant CM, Sims PFG, Pavitt GD & Hubbard SJ (2014) . Nucleic Acids Research, 42(2), 1026-1041.
  • Castelli LM, Lui J, Campbell SG, Rowe W, Zeef LAH, Holmes LEA, Hoyle NP, Bone J, Selley JN, Sims PFG & Ashe MP (2011) . Molecular Biology of the Cell , 22(18), 3379-3393.
  • Cridge AG, Castelli LM, Smirnova JB, Selley JN, Rowe W, Hubbard SJ, McCarthy JEG, Ashe MP, Grant CM & Pavitt GD (2010) . Nucleic Acids Research, 38(22), 8039-8050.
  • JONES JT, KUMAR A, PYLYPENKO LA, THIRUGNANASAMBANDAM A, CASTELLI L, CHAPMAN S, COCK PJA, GRENIER E, LILLEY CJ, PHILLIPS MS & BLOK VC (2009) . Molecular Plant Pathology, 10(6), 815-828.
  • Hoyle NP, Castelli LM, Campbell SG, Holmes LEA & Ashe MP (2007) . Journal of Cell Biology, 179(1), 65-74.
  • Castelli L, Bryan G, Blok VG, Ramsay G, Sobczak M, Gillespie T & Phillips MS (2006) . Nematology, 8(1), 103-110.
  • Ramsay G, Bryan G, Castelli L, Phillips M & Blok V (2005) . Nematology, 7(5), 689-699.
  • Blok V, Bryan G, Phillips M, Castelli L & Ramsay G (2005) . Nematology, 7(5), 701-711.
  • Castelli L, Ramsay G, Bryan G, Neilson SJ & Phillips MS (2003) . Euphytica, 129(3), 377-386.
  • Bryan G, McLean K, Bradshaw J, De Jong W, Phillips M, Castelli L & Waugh R (2002) . Theoretical and Applied Genetics, 105(1), 68-77.
  • Tudisca V, Simpson C, Castelli L, Lui J, Hoyle N, Moreno S, Ashe M & Portela P () . Journal of Cell Science.

Book chapters

  • (2024) , International Review of Neurobiology (pp. 209-268). Elsevier

Conference proceedings

  • Cooper-Knock J, Moll T, Ramesh T, Castelli L, Shaw C, Al-Chalabi A, McDermott C, Hautbergue G & Shaw P (2019) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 90(12) (pp e10.3-e11)
  • Cooper-Knock J, Moll T, Ramesh T, Castelli L, Shaw C, Al-Chalabi A, McDermott C, Hautbergue G & Shaw P (2019) MUTATIONS IN THE GLYCOSYLTRANSFERASE DOMAIN OF GLT8D1 CAUSE ALS. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 90(12) (pp E20-E21)
  • Alves-Cruzeiro J, Karyka E, Bauer C, Coldicott I, Hautbergue G, Webster C, Castelli L, Simon S, Myszczynska M, Ferraiuolo L & Azzouz M (2019) AAV-mediated gene editing as a potential therapeutic approach for C9ORF72-linked ALS/FTD. HUMAN GENE THERAPY, Vol. 30(11) (pp A96-A96)
  • Allen SP, Hall B, Castelli L, Francis L, Woof R, Higginbottom A, Myszczynska M, Allen CF, Stopford MJ, Webster CP , De Vos K et al (2018) . Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1859(Supplement) (pp e23-e23). Budapest, Hungary, 25 August 2018 - 25 August 2018.

Datasets

  • Gatto N, Souza CDS, Bell S, Shaw A, Myszczynska M, Powers S, Meyer K, Heath P, Castelli L, Karyka E , Mortiboys H et al .

Preprints

  • Lin Y-H, Dodd JE, Cutillo L, Castelli LM, Mihaylov SR, Norris K, Higginbottom A, Walsh MJ, Cooper-Knock J, Highley JR , Granata I et al (2024) , Cold Spring Harbor Laboratory.
  • Burrows DJ, McGown A, Abduljabbar O, Castelli LM, Shaw PJ, Hautbergue GM & Ramesh TM (2024) , Cold Spring Harbor Laboratory.
  • Mihaylov SR, Castelli LM, Lin Y-H, Gül A, Soni N, Hastings C, Flynn HR, Dickman MJ, Snijders AP, Bandmann O , Mortiboys H et al (2021) , Cold Spring Harbor Laboratory.
  • Castelli LM, Sanchez-Martinez A, Lin Y-H, Upadhyay SK, Higginbottom A, Cooper-Knock J, Gül A, Walton A, Montmasson C, Cohen R , Bauer CS et al (2021) , Cold Spring Harbor Laboratory.
  • Castelli LM, Cutillo L, Souza CDS, Sanchez-Martinez A, Granata I, Myszczynska MA, Heath PR, Livesey MR, Ning K, Azzouz M , Shaw PJ et al (2021) , Cold Spring Harbor Laboratory.
  • Cooper-Knock J, Moll T, Ramesh T, Castelli L, Beer A, Robins H, Fox I, Niedermoser I, Van Damme P, Robberecht W , Hardiman O et al () .