Professor Li Su
School of Medicine and Population Health
Professor of Neuroimaging
  
  +44 114 21 59108
Full contact details
School of Medicine and Population Health
Sheffield Institute for Translational Neuroscience (SITraN)
385a Glossop Road
Sheffield
S10 2HQ
- Profile
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Professor Su was awarded a PhD in Computational Neuroscience from University of Kent in 2009. After several years of postdoctoral research in Institute of Psychiatry at King¡¯s College London, MRC Cognition and Brain Sciences Unit and University of Cambridge, he was awarded a highly competitive Senior Research Fellowship from Alzheimer¡¯s Research UK in 2017.
He leads the Artificial Intelligence & Computational Neuroscience Group, which aims to combine innovative and original computational methods with the state-of-the-art brain imaging techniques such as MEG/EEG, 7T MRI and PET in understanding, detecting and developing treatments and care for neurological and psychiatric conditions.
In 2020, he was appointed Professor of Neuroimaging at the University of Sheffield. He also holds a part-time PI position in Department of Psychiatry at University of Cambridge. His research has been recognised through international awards including an International College of Geriatric Psychoneuropharmacology Junior Investigator Award in 2015.
 
- Research interests
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- Conduct multimodal and longitudinal EEG, MRI and PET studies to discover clinically relevant biomarkers for neurodegenerative disorders (including Parkinson¡¯s disease, Alzheimer¡¯s disease), motor neuron disorders, stroke and other related conditions. Apply machine learning and other advanced imaging analysis to the imaging, genetic, blood and other clinical data.
 - Develop advanced imaging analysis methods for basic and clinical neuroscience.
 - Develop and validate AI models using clinical and neuroimaging data. Use the model to predict therapeutic effects of potential drug targets on normalising neural network functions from computer simulations.
 - Early detection and prevention of dementia. In particular, apply multimodal imaging and VR to find earliest signals for functional declines and pathological abnormalities. Develop and test pharmaceutical and non-pharmaceutical interventions to slow or reverse disease progression for those with increased risk of developing dementia.
 
 
- Publications
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Journal articles
- . Information Fusion, 126, 103658-103658.
 - . Brain and Behavior, 15(10).
 - . Journal of Biomedical Optics, 30(S2).
 - . Scientific Reports, 15(1).
 - . Nutrients, 17(13).
 - . Neurological Sciences, 46(9), 4233-4257.
 - . Brain Stimulation, 18(3), 987-989.
 - . BMJ Open, 15(3).
 - . Alzheimer's & Dementia, 21(2).
 - . Journal of Cerebral Blood Flow & Metabolism, 45(6), 1048-1058.
 - . Biomedical Signal Processing and Control, 99, 106797-106797.
 - . The Journal of Neuroscience, 45(5), e2139232024-e2139232024.
 - . Neural Regeneration Research, 20(12), 3388-3399.
 - . Journal of Alzheimer¡¯s Disease, 103(1), 167-179.
 - . Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 20(S2).
 - . Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 20(S9).
 - . The Lancet Healthy Longevity, 5(12), 100665-100665.
 - . Discover Public Health, 21.
 - . Brain Communications, 6(6).
 - . Journal of Clinical Medicine, 13(22).
 - . European Journal of Public Health, 34(Supplement_3).
 - . Ageing Research Reviews, 101, 102510-102510.
 - . Journal of Clinical Medicine, 13(17).
 - . JAMA Network Open, 7(8).
 - . Human Brain Mapping, 45(11).
 - . Brain Communications, 6(3).
 - . Behavioural Brain Research, 469, 115050-115050.
 - . Brain Communications, 6(3).
 - . Brain Communications, 6(3).
 - . Alzheimer's & Dementia, 20(4), 2779-2793.
 - . Brain Communications, 6(1).
 - . Cerebral Circulation - Cognition and Behavior, 6, 100050-100050.
 - . Cerebral Circulation - Cognition and Behavior, 6, 100293-100293.
 - . Ageing Research Reviews, 93.
 - . Alzheimer's & Dementia, 19(S17).
 - . Alzheimer's & Dementia, 19(S16).
 - . Alzheimer's & Dementia, 19(S16).
 - . Alzheimer's & Dementia, 19(S23).
 - . Alzheimer's & Dementia, 19(S16).
 - . Alzheimer's & Dementia, 19(S17).
 - . Alzheimer's & Dementia, 19(S12).
 - . Alzheimer's & Dementia, 19(S16).
 - . Alzheimer's & Dementia, 19(S10).
 - . Alzheimer's & Dementia, 19(S10).
 - . Alzheimer's & Dementia, 19(S10).
 - . Brain, 147(1), 267-280.
 - . Brain Communications, 5(5).
 - . Stroke, 54(10), 2676-2687.
 - . Journal of Neurology, 270, 4949-4958.
 - . Ageing Research Reviews, 90, 101992-101992.
 - . Movement Disorders, 38(8), 1493-1502.
 - . Journal of Cerebral Blood Flow & Metabolism, 43(10), 1672-1684.
 - . Alzheimer's Research & Therapy, 15.
 - . Neurophotonics, 10(02).
 - . NMR in Biomedicine, 36(7).
 - . Frontiers in Computational Neuroscience, 16.
 - . Alzheimer's & Dementia, 18(S7).
 - . Alzheimer¡¯s Research & Therapy, 14(1).
 - . Frontiers in Aging Neuroscience, 14.
 - . Ageing Research Reviews, 79, 101651-101651.
 - . Frontiers in Computational Neuroscience, 16.
 - . Brain Communications, 4(3).
 - . Journal of Neurology, 269, 4299-4309.
 - . Brain, 145(6), 2190-2205.
 - . Journal of Alzheimer's Disease, 85(4), 1573-1582.
 - . Journal of Neurology, Neurosurgery & Psychiatry, 93(5), 481-490.
 - . Journal of Neurology, Neurosurgery & Psychiatry, 93(6), 651-658.
 - . Autonomic Neuroscience, 237.
 - . Alzheimer's & Dementia, 17(S4).
 - . Alzheimer's & Dementia, 17(S10).
 - . Journal of Cerebral Blood Flow & Metabolism, 41(11), 2844-2855.
 - . Neuroscience & Biobehavioral Reviews, 129, 142-153.
 - . The American Journal of Psychology, 134(2), 167-174.
 - . Information Fusion, 67, 116-124.
 - . NeuroImage, 229, 117749-117749.
 - . Journal of Neurology, 268(5), 1962-1971.
 - . International Journal of Geriatric Psychiatry, 36(6), 831-838.
 - . Neurobiology of Aging, 101, 172-180.
 - . Neurobiology of Aging, 98, 124-133.
 - . Journal of Neurology, Neurosurgery & Psychiatry, 92(1), 16-21.
 - . Journal of Neurology, Neurosurgery & Psychiatry, 92(1), 45-52.
 - . Alzheimer's & Dementia, 16(S5).
 - . Alzheimer's & Dementia, 16(S4).
 - . Alzheimer's & Dementia, 16(S4).
 - . Alzheimer's & Dementia, 16(S5).
 - . Alzheimer's & Dementia, 16(S4).
 - . Alzheimer's & Dementia, 16(S4).
 - . Alzheimer's & Dementia, 16(S4).
 - . Alzheimer's & Dementia, 16(S5).
 - . Molecular Neurodegeneration, 15(1).
 - . Journal of Neurology, Neurosurgery & Psychiatry, 91(8), 861-866.
 - . Journal of Neurology, 267(11), 3282-3286.
 - . Brain and Cognition, 143, 105584-105584.
 - . Journal of Alzheimer¡¯s Disease, 75(4), 1211-1218.
 - . Brain, 143(5), 1588-1602.
 - . International Journal of Psychology, 55(6), 1011-1015.
 - . Neurobiology of Aging, 91, 36-44.
 - . NeuroImage: Clinical, 25, 102200-102200.
 - . Information Fusion, 58, 153-167.
 - . Neuroscience Letters, 716, 134683-134683.
 - . Journal of Neurology, Neurosurgery & Psychiatry, 91(2), 158-161.
 - . Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 11(1), 690-699.
 - . Social Influence, 14(3-4), 133-146.
 - . Journal of Geriatric Psychiatry and Neurology, 32(6), 354-364.
 - . BMJ Open, 9(7), e028188-e028188.
 - . The Journal of Neuroscience, 39(36), 7218-7226.
 - . Alzheimer's & Dementia, 15(7S_Part_14).
 - The endowment effect in the genes: An exploratory study. Judgment and Decision Making, 14(3), 293-298.
 - . NeuroImage, 184, 317-334.
 - . Brain, 141(12), 3415-3427.
 - . Alzheimers Dement (Amst), 10, 678-687.
 - . Journal of Alzheimer's Disease, 65(3), 885-896.
 - . Alzheimer's & Dementia, 14(7S_Part_23).
 - . Alzheimer's & Dementia, 14(7S_Part_2).
 - . Neurology, 90(22).
 - . Journal of Neurology, 265(7), 1528-1539.
 - . Alzheimer's & Dementia, 14(2), 253-258.
 - . Journal of Alzheimer's Disease, 61(1), 415-424.
 - . Alzheimer's & Dementia, 13(7S_Part_19).
 - . Alzheimer's & Dementia, 13(10), 1089-1097.
 - . Ageing Research Reviews, 36, 88-104.
 - . Neurobiology of Aging, 55, 78-90.
 - . International Psychogeriatrics, 29(4), 545-555.
 - . BMJ Open, 7(1), e013187-e013187.
 - . Ageing Research Reviews, 35, 250-264.
 - . British Journal of Psychiatry, 209(6), 525-526.
 - . Psychiatry Research: Neuroimaging, 254, 127-136.
 - . Current Alzheimer Research, 13(5), 534-544.
 - . The American Journal of Geriatric Psychiatry, 24(2), 136-143.
 - . Journal of the American Statistical Association, 110(512), 1375-1388.
 - . Brain, 138(10), 2974-2986.
 - . Alzheimer's & Dementia, 11(7S_Part_13).
 - . Alzheimer's & Dementia, 11(7S_Part_15).
 - . Alzheimer's & Dementia, 11(7S_Part_1).
 - . Parkinsonism & Related Disorders, 21(8), 862-870.
 - . NeuroImage: Clinical, 7, 456-462.
 - . Neurobiology of Aging, 36(4), 1743-1750.
 - . Human Brain Mapping, 36(3), 1190-1201.
 - . Journal of Neurology, 262(1), 165-172.
 - . Formal Aspects of Computing, 26(6), 1169-1204.
 - . Alzheimer's Research & Therapy, 6(2), 18-18.
 - . NeuroImage, 88, 113-124.
 - . Journal of Cognitive Neuroscience, 25(10), 1678-1691.
 - . Neuroscience, 169(1), 171-181.
 - . Formal Aspects of Computing, 21(6).
 - . Electronic Notes in Theoretical Computer Science, 208, 95-111.
 - . Electronic Notes in Theoretical Computer Science, 139(1), 25-47.
 - . Frontiers in Psychiatry, 12.
 - . Frontiers in Aging Neuroscience, 13.
 - . Scientific Reports, 9(1).
 - . Frontiers in Human Neuroscience, 12.
 - . Frontiers in Aging Neuroscience, 10.
 - . Neuropsychology, 32(6), 764-776.
 - . PLOS Computational Biology, 13(9), e1005617-e1005617.
 - . Brain, aww340-aww340.
 - . Frontiers in Computational Neuroscience, 10.
 - . Translational Psychiatry, 6(8), e877-e877.
 - . Scientific Reports, 6(1).
 - . Frontiers in Computational Neuroscience, 9.
 - . Scientific Reports, 5(1).
 - . Frontiers in Neuroscience, 8.
 - . PLoS Computational Biology, 10(4), e1003553-e1003553.
 - . PLoS ONE, 9(3), e90595-e90595.
 - . Neuropsychology, 28(3), 373-381.
 - . PLoS ONE, 8(1), e54258-e54258.
 - . Frontiers in Psychology, 2.
 
Book chapters
- , Lecture Notes in Computer Science (pp. 13-23). Springer Nature Switzerland
 - , Lecture Notes in Computer Science (pp. 184-193). Springer Nature Switzerland
 - , Advances in Magnetic Resonance Technology and Applications (pp. 321-336). Elsevier
 - , Springer Series in Cognitive and Neural Systems (pp. 113-126). Springer International Publishing
 - , Human Attention in Digital Environments (pp. 114-144). Cambridge University Press
 - , Lecture Notes in Computer Science (pp. 504-509). Springer Berlin Heidelberg
 
Conference proceedings
- . Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Vol. 20(S2). Philadelphia, USA, 28 July 2024 - 28 July 2024.
 - . Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Vol. 20(S2). Philadelphia, USA, 28 July 2024 - 28 July 2024.
 - . Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Vol. 20(S2). United States, 28 July 2024 - 28 July 2024.
 - . Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Vol. 20(S9). Philadelphia, USA, 28 July 2024 - 28 July 2024.
 - . Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Vol. 20(S9). Philadelphia, USA, 28 July 2024 - 28 July 2024.
 - . Neural Imaging and Sensing 2024 (pp 142-142), 27 January 2024 - 1 February 2024.
 - . 2012 Second International Workshop on Pattern Recognition in NeuroImaging (pp 97-100), 2 July 2012 - 4 July 2012.
 - . ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
 
Preprints
- , Cold Spring Harbor Laboratory.
 - , Cold Spring Harbor Laboratory.
 - , Cold Spring Harbor Laboratory.
 - , Research Square Platform LLC.
 - , Center for Open Science.
 - , Cold Spring Harbor Laboratory.
 - , Cold Spring Harbor Laboratory.
 - , Cold Spring Harbor Laboratory.
 - , Cold Spring Harbor Laboratory.
 - , Cold Spring Harbor Laboratory.
 - , Cold Spring Harbor Laboratory.
 - , Research Square Platform LLC.
 - , Cold Spring Harbor Laboratory.
 - , Cold Spring Harbor Laboratory.
 - , Cold Spring Harbor Laboratory.
 - , Cold Spring Harbor Laboratory.
 
 
- Grants
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Principal funding sources:
- Alzheimer¡¯s Research UK
 - Alzheimer¡¯s Society
 - The Lewy Body Society
 - Addenbrooke¡¯s Charitable Trust
 - Isaac Newton Trust
 - UKRI MRC, BBSRC and EPSRC
 - NIHR
 - Stroke Association
 
 
Links