Joseph Scarrott

PhD

School of Medicine and Population Health

Process Development Scientist

Joe Scarrott
Profile picture of Joe Scarrott
Research interests

Gene Therapy

Viral Vector Development

Viral Vector Manufacturing

Publications

Journal articles

  • Wiseman JP, Scarrott JM, Alves-Cruzeiro J, Saffari A, Böger C, Karyka E, Dawes E, Davies AK, Marchi PM, Graves E , Fernandes F et al (2024) . EMBO Molecular Medicine, 16(11), 2882-2917.
  • Johari YB, Pohle TH, Whitehead J, Scarrott JM, Liu P, Mayer A & James DC (2024) . Biotechnology Journal, 19(6).
  • Scarrott JM, Alves-Cruzeiro J, Marchi PM, Webster CP, Yang Z-L, Karyka E, Marroccella R, Coldicott I, Thomas H & Azzouz M (2023) . Brain Communications, 5(1).
  • Scarrott JM, Johari YB, Pohle TH, Liu P, Mayer A & James DC (2022) . Biotechnology Journal.
  • Johari YB, Scarrott JM, Pohle TH, Liu P, Mayer A, Brown AJ & James DC (2022) . Biotechnology Journal, 17(8).
  • Johari YB, Jaffé SRP, Scarrott JM, Johnson AO, Mozzanino T, Pohle TH, Maisuria S, Bhayat‐Cammack A, Lambiase G, Brown AJ , Tee KL et al (2021) . Biotechnology and Bioengineering, 118(2), 1013-1021.
  • Behne R, Teinert J, Wimmer M, D’Amore A, Davies AK, Scarrott JM, Eberhardt K, Brechmann B, Chen IP-F, Buttermore ED , Barrett L et al (2020) . Human Molecular Genetics, 29(2), 320-334.
  • Iannitti T, Scarrott J, Likhite S, Coldicott IRP, Lewis KE, Heath PR, Higginbottom A, Myszczynska MA, Milo M, Hautbergue GM , Meyer K et al (2018) . Molecular Therapy : Nucleic Acids, 12, 75-88.
  • Scarrott JM, Herranz-Martín S, Alrafiah AR, Shaw PJ & Azzouz M (2015) . Expert Opinion on Biological Therapy.

Book chapters

  • Chandran JS, Scarrott JM, Shaw P & Azzouz M (2017) Gene Therapy in the Nervous System: Failures and Successes In El-Khamisy S (Ed.), Personalised Medicine Lessons from Neurodegeneration to Cancer Springer
  • Chandran JS, Scarrott JM, Shaw PJ & Azzouz M (2017) , Personalised Medicine (pp. 241-257).

Conference proceedings

  • Wiseman J, Alves-Cruzeiro J, Scarrott JM, Karyka E, Marchi PM, Graves E, Webster CP, Yang Z, Coldicott I, Dawes E , Shaw PJ et al (2024) AAV9-mediated gene replacement therapy for spastic paraplegia 47. Human Gene Therapy, Vol. 35(3-4) (pp A181-A182). Brussels, Belgium, 24 October 2023 - 24 October 2023.
  • Wiseman J, Cruzeiro J, Scarrott J, Karyka E, Marchi P, Webster CP, Yang Z, Coldicott I, Shaw PJ, Ferraiuolo L & Azzouz M (2022) Gene Replacement Therapy for Spastic Paraplegia 47. HUMAN GENE THERAPY, Vol. 33(23-24) (pp A26-A27)
  • Scarrott JM, Johari YB, Pohle TH, Liu P, Mayer A & James DC (2022) Small molecule chemical additives for enhanced recombinant AAV production in HEK293 cells. HUMAN GENE THERAPY, Vol. 33(23-24) (pp A105-A105)
  • Scarrott JM, Coldicott I, Davies A, Hirst J, Karyka E, Bauer C & Azzouz M (2019) Development of an AAV9-mediated gene therapy for hereditary spastic paraplegia 47. HUMAN GENE THERAPY, Vol. 30(8) (pp A18-A18)
  • Scarrott J, Ferraiuolo L, Heath P, Gelsthorpe C, Kaspar B, Shaw DP & Azzouz M (2016) Investigating the Specificity of RNAi Molecules in Human Gene Therapy for Superoxide Dismutase 1-linked Familial Amyotrophic Lateral Sclerosis. HUMAN GENE THERAPY, Vol. 27(7) (pp A16-A17)

Patents

  • Azzouz M, Scarrott J & Karyka E (2021) Gene Therapy Treatment. WO2021205028A1 Appl. 14 Oct 2021.

Preprints

  • Scarrott J, Johari YB, Pohle T, Liu P, Mayer A & James D (2022) , Wiley.
  • Johari YB, Jaffé SRP, Scarrott JM, Johnson AO, Mozzanino T, Pohle TH, Maisuria S, Bhayat-Cammack A, Brown AJ, Tee KL , Jackson PJ et al (2020) , Cold Spring Harbor Laboratory.
  • Johari Y, Jaffe S, Scarrott J, Johnson A, Mozzanino TO, Pohle T, Maisuria S, Cammack AB, Brown A, Tee KL , Jackson P et al (2020) , Wiley.
  • Tee KL, Jackson PJ, Scarrott JM, Jaffe SRP, Johnson AO, Johari Y, Pohle TH, Mozzanino T, Price J, Grinham J , Brown A et al (2020) , Cold Spring Harbor Laboratory.