Dr Lucy Urwin

BSc, PhD

School of Medicine and Population Health

Postdoctoral Research Associate

Lucy Urwin
Profile picture of Lucy Urwin
l.urwin@sheffield.ac.uk
LU108, The Medical School

Full contact details

Dr Lucy Urwin
School of Medicine and Population Health
LU108
The Medical School
Beech Hill Road
Sheffield
S10 2RX
Profile

I am an early career post-doctoral researcher, currently working within the Clinical Infection Research Group (CIRG) as part of the Darton lab. The Darton lab is interested in characterising adaptive immune responses to Staphylococcus aureus infections, with the aim of identifying correlates of protection that can inform vaccine development. As part of this I’ve been helping to set up a human challenge study and developing tools for studying antigen-specific IgG responses to S. aureus.

Prior to joining the Darton lab, I worked in the Corrigan lab, studying the (p)ppGpp-mediated stringent response and the role this conserved bacterial stress response plays in S. aureus colonisation and infection. My PhD project was also rooted in infection biology and involved the development of in vitro tissue culture models of the corneal epithelium that could be used to simulate S. aureus/P. aeruginosa corneal infections (bacterial keratitis) and test novel antimicrobials. 

Therefore, throughout my research career I have developed particular expertise in staphylococcal biology and the use of tissue culture models for studying S. aureus pathogenesis.

Qualifications

BSc in Molecular Biology

PhD in Infection Biology: The Development of in vitro Corneal Infection Models for Antimicrobial Drug Testing 

Publications

Journal articles

  • Choudhury NR, Urwin L, Salamaga B, Prince LR, Renshaw SA & Corrigan RM (2025) . The Journal of Infectious Diseases.
  • Urwin L, Savva O & Corrigan RM (2024) . Microbiology, 170(7).
  • Jadi PK, Dave A, Issa R, Tabbasum K, Okurowska K, Samarth A, Urwin L, Green LR, Partridge LJ, MacNeil S , Garg P et al (2024) . The Ocular Surface, 32, 211-218.
  • Green LR, Issa R, Albaldi F, Urwin L, Thompson R, Khalid H, Turner CE, Ciani B, Partridge LJ & Monk PN (2023) . mBio, 14(4).
  • Carrilero L, Urwin L, Ward E, Choudhury NR, Monk IR, Turner CE, Stinear TP & Corrigan RM (2023) . Microbiology Spectrum, 11(2).
  • Nolan AC, Zeden MS, Kviatkovski I, Campbell C, Urwin L, Corrigan RM, Gründling A & O’Gara JP (2023) . mBio, 14(1).
  • Partridge LJ, Urwin L, Nicklin MJH, James DC, Green LR & Monk PN (2021) . Cells, 10(6).
  • Urwin L, Okurowska K, Crowther G, Roy S, Garg P, Karunakaran E, MacNeil S, Partridge LJ, Green LR & Monk PN (2020) . Cells, 9(11).

Preprints

  • Choudhury NR, Urwin L, Salamaga B, Prince LR, Renshaw SA & Corrigan RM (2023) , Cold Spring Harbor Laboratory.
  • Green LR, Issa R, Albaldi F, Urwin L, Khalid H, Turner CE, Ciani B, Partridge LJ & Monk PN (2023) , Cold Spring Harbor Laboratory.
  • Nolan AC, Zeden MS, Campbell C, Kviatkovski I, Urwin L, Corrigan RM, Gründling A & O’Gara JP (2022) , Cold Spring Harbor Laboratory.
  • Partridge LJ, Urwin L, Nicklin MJH, James DC, Green LR & Monk PN (2020) , Cold Spring Harbor Laboratory.