Professor Ian Peake
School of Medicine and Population Health
Emeritus Professor of Molecular Medicine
+44 7785 247 928
Full contact details
School of Medicine and Population Health
The Medical School
Beech Hill Road
Sheffield
S10 2RX
- Profile
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For enquiries please contact - SMPH-West-Operational@sheffield.ac.uk
I joined the University in 1990 as the Sir Edward Mellanby Professor of Molecular Medicine and also hold an Honorary Consultant position with the Sheffield Teaching Hospitals NHS Foundation Trust. I have been Deputy Director of the Division of Genomic Medicine and Director of Research for Medicine.
I am currently focused on my research into inherited bleeding disorders in particular von Willebrands disease.
- Research interests
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My research interests are inherited disorders of Haemostasis and Thrombosis.
My current research interests focus on von Willebrands Disease. I was a co-applicant on an NIH funded PPG (the Zimmerman Project) with collaborators in Canada and USA. I also co-chaired the EU von Willebrands disease collaborative group which has projects continuing from the EU funded MCMDM-1VWD project which I directed.
Since 2011 I have been a coordinator of an International EU/Iran study of severe Von Willebrands Disease (3WINTERS IPS) sponsored by the a Medical research Charity in Milan Italy.
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- . Journal of Thrombosis and Haemostasis, 18(9), 2145-2154.
- . Blood Advances, 2(13), 1585-1594.
- . Haemophilia.
- . Blood, 127(20), 2481-2488.
- . Thrombosis and Haemostasis, 110(2), 264-274.
- . Blood, 121(12), 2336-2339.
- . Journal Of Thrombosis And Haemostasis, 8(9), 1986-1993.
- . Journal of Thrombosis and Haemostasis, 8(1), 13-16.
- . Journal of Thrombosis and Haemostasis, 6(5), 762-771.
- . Blood, 111(7), 3531-3539.
- . Journal of Thrombosis and Haemostasis, 5, 7-11.
- . Blood, 109(1), 112-121.
- . Journal of Thrombosis and Haemostasis, 4(4), 774-782.
- . Journal of Thrombosis and Haemostasis, 4(4), 766-773.
Conference proceedings
- . Blood, Vol. 132(Supplement 1) (pp 2464-2464)
All publications
Journal articles
- . Blood Advances, 5(15), 2987-3001.
- . Journal of Thrombosis and Haemostasis, 18(9), 2145-2154.
- . Blood Advances, 4(13), 2979-2990.
- . Blood Advances, 2(13), 1585-1594.
- . Haemophilia.
- . Blood, 127(20), 2481-2488.
- . PLoS ONE, 10(12).
- . Thrombosis and Haemostasis, 110(2), 264-274.
- . Blood, 121(12), 2336-2339.
- Applying in silico analysis to the historically reported VWF exon 42 deletion reveals a probable L1 non-autonomous retrotransposition mediated deletion pathomechanism. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 11, 175-175.
- . Blood, 120(21), 99-99.
- . Haemophilia, 18(s6), 1-13.
- . Journal of Thrombosis and Haemostasis, 9(3), 603-605.
- . Haemophilia, 17(1), 165-166.
- . Haematologica, 95(12), 2163-2165.
- . Blood, 116(21), 2218-2218.
- . Journal Of Thrombosis And Haemostasis, 8(9), 1986-1993.
- . British Journal of Haematology, 151(3), 245-251.
- . Thrombosis Research, 126(3), 227-231.
- . Journal of Thrombosis and Haemostasis, 8(1), 13-16.
- . Blood, 113(17), 4110-4113.
- . Journal of Thrombosis and Haemostasis, 7(8), 1304-1312.
- . Haemophilia, 14(3), 621-624.
- . Blood, 111(10), 4979-4985.
- . Journal of Thrombosis and Haemostasis, 6(5), 762-771.
- . Blood, 111(7), 3531-3539.
- . Journal of Thrombosis and Haemostasis, 5, 7-11.
- . Journal of Thrombosis and Haemostasis, 5(4), 715-721.
- . Haematologica, 92(4), 550-553.
- . Blood, 109(1), 112-121.
- . British Journal of Haematology, 135(4), 538-546.
- . Journal of Thrombosis and Haemostasis, 4(10), 2103-2114.
- . Journal of Thrombosis and Haemostasis, 4(4), 774-782.
- . Journal of Thrombosis and Haemostasis, 4(4), 766-773.
- . Haemophilia, 11(2), 145-163.
- . Blood, 104(8), 2359-2367.
- . Haemophilia, 10(3), 199-217.
- . Haemophilia, 10(3), 218-231.
- . British Journal of Haematology, 124(6), 843-844.
- . Journal of Thrombosis and Haemostasis, 1, P1662-P1662.
- . British Journal of Haematology, 123(4), 749-750.
- . British Journal of Haematology, 121(5), 775-777.
- . British Journal of Haematology, 120(3), 464-470.
- . Seminars in Thrombosis and Hemostasis, 29(1), 023-030.
- . Clinical & Laboratory Haematology, 24(4), 197-204.
- . Blood, 100(1), 364-364.
- . Human Molecular Genetics, 11(7), 723-731.
- . Thrombosis and Haemostasis, 85(05), 929-931.
- . Hemoglobin, 25(3), 337-340.
- . British Journal of Haematology, 113(4), 1076-1077.
- . British Journal of Haematology, 113(4), 983-988.
- Routine use of RT-PCR for the detection of TCR gene rearrangement. LEUKEMIA, 15(12), 2010-2010.
- Novel c-fms mutations in acute and chronic myeloproliferative disorders. Blood, 98(11 PART I).
- . The American Journal of Human Genetics, 69(1), 75-87.
- . Best Practice & Research Clinical Haematology, 14(2), 235-240.
- . Biochemical and Biophysical Research Communications, 280(2), 448-453.
- . Thrombosis and Haemostasis, 83(06), 844-848.
- Relationship between factor VIII mutation type and inhibitor development in a cohort of previously untreated patients treated with recombinant factor VIII (Recombinate). Recombinate PUP Study Group.. Thromb Haemost, 83(6), 844-848.
- . Thrombosis and Haemostasis, 83(05), 715-721.
- . British Journal of Haematology, 111(1), 190-195.
- . British Journal of Haematology, 111(4), 1109-1111.
- . British Journal of Haematology, 110(1), 135-138.
- . British Journal of Haematology, 111(4), 1109-1111.
- . British Journal of Haematology, 111(1), 190-195.
- . Blood, 96(2), 560-568.
- . Blood, 96(2), 560-568.
- . Blood, 95(6), 2000-2007.
- . Blood, 95(6), 1935-1941.
- . Thrombosis and Haemostasis, 82(09), 1061-1064.
- . Thrombosis and Haemostasis, 81(03), 462-462.
- . Thrombosis and Haemostasis, 82(10), 1373-1375.
- . British Journal of Haematology, 105(4), 894-900.
- . British Journal of Haematology, 104(4), 915-918.
- Intensity of prior therapy influences minimal residual disease (MRD) detection and its clinical significance in childhood lymphoblastic leukaemia (ALL).. BLOOD, 94(10), 203B-203B.
- . Human Mutation, 14(4), 304-311.
- Major structural defects in the antithrombin gene in four families with type I antithrombin deficiency. THROMBOSIS AND HAEMOSTASIS, 517-518.
- The 46 allele of the-675 4G/5G dimorphism in the PAI-1 promoter increases thrombotic risk in patients with factor V Leiden. THROMBOSIS AND HAEMOSTASIS, 668-668.
- Mutational analysis of the von Willebrand factor gene in 27 families from Turkey with von Willebrand disease. THROMBOSIS AND HAEMOSTASIS, 283-283.
- Increased prevalence of compound heterozygosity for the C677T and A1289C dimorphisms in the methylene tetrahydrofolate reductase gene in patients with factor V Leiden and venous thrombosis. THROMBOSIS AND HAEMOSTASIS, 71-71.
- CYS788ARG and CYS1225GLY mutations in von Willebrand factor result in combined type 1 and type 2N von Willebrand disease. THROMBOSIS AND HAEMOSTASIS, 686-686.
- Arg273Trp mutation in the von Willebrand factor propeptide results in impaired secretion. THROMBOSIS AND HAEMOSTASIS, 687-687.
- Minimal residual disease clearance in standard risk childhood ALL patients treated on UKALL X and XI protocols.. BRITISH JOURNAL OF HAEMATOLOGY, 105, 80-80.
- Rapid detection of factor IX gene mutations using conformation sensitive gel electrophoresis.. BRITISH JOURNAL OF HAEMATOLOGY, 105, 36-36.
- . Thrombosis and Haemostasis, 79(04), 723-726.
- . Thrombosis and Haemostasis, 79(06), 1086-1091.
- . Thrombosis and Haemostasis, 79(04), 762-766.
- . Haemophilia, 4(s2), 24-25.
- . Haemophilia, 4(4), 346-349.
- Influence of post-induction treatment intensity on rates of minimal residual disease clearance in childhood ALL.. BLOOD, 92(10), 394A-394A.
- Diagnosis and thrombotic risk in a cohort with genetically confirmed protein S deficiency.. BLOOD, 92(10), 561A-561A.
- c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukaemia.. BLOOD, 92(10), 592A-593A.
- Recombinate PUP mutation study: Examination of the relationship between factor VIII mutations and inhibitor development.. BLOOD, 92(10), 102B-102B.
- . Blood, 92(8), 2696-2706.
- . Blood, 92(8), 2696-2706.
- . Blood, 92(7), 2334-2337.
- . Blood, 92(7), 2334-2337.
- Genetic carrier state diagnosis of haemophilia: Experience at the Haemophilia Centre in Castelfranco Veneto. THROMBOSIS RESEARCH, 91(3), S63-S64.
- Late relapsing childhood acute lymphoblastic leukaemia.. BRITISH JOURNAL OF HAEMATOLOGY, 101, 31-31.
- c-kit mutational analysis in acute and chronic myeloproliferative disorders.. BRITISH JOURNAL OF HAEMATOLOGY, 101, 28-28.
- Pro2063Ser mutation in von Willebrand factor results in impaired intracellular transport and secretion.. BRITISH JOURNAL OF HAEMATOLOGY, 101, 67-67.
- . Thrombosis and Haemostasis, 78(06), 1426-1429.
- . Thrombosis and Haemostasis, 77(02), 234-237.
- HLA class II profile: a weak determinant of factor VIII inhibitor development in severe haemophilia A. UKHCDO Inhibitor Working Party.. Thromb Haemost, 77(2), 234-237.
- . British Journal of Haematology, 98(4), 992-994.
- Late relapsing childhood lymphoblastic leukaemia.. BLOOD, 90(10), 2492-2492.
- . Blood Coagulation & Fibrinolysis, 8(7), 469-469.
- . Clinical Science, 93(s37), 10P-10P.
- The C677F polymorphism in the methylene tetrahydrofolate reductase gene: Interaction with factor V Leiden in thrombophilia patients. THROMBOSIS AND HAEMOSTASIS, P2154-P2154.
- Influence of founder effect and mutations causing borderline phenotypes on the prevalence of antithrombin deficiency in thrombophilic patients. THROMBOSIS AND HAEMOSTASIS, P1764-P1764.
- Two novel polymorphisms in the promoter region of the factor IX gene show differential binding of nuclear factors. THROMBOSIS AND HAEMOSTASIS, P1881-P1881.
- Association between Msel RFLP genotype and factor IX level in normal females; evidence for a polymorphic oestrogen response element in the factor IX gene promoter. THROMBOSIS AND HAEMOSTASIS, P1882-P1882.
- Co-inheritance of the 20210A allele of the prothrombin gene increases the thrombotic risk in subjects with familial thrombophilia. THROMBOSIS AND HAEMOSTASIS, SC672-SC672.
- The prothrombin 20210 G->A variant is associated with increased levels of prothrombin and increased incidence of venous thrombosis. THROMBOSIS AND HAEMOSTASIS, O1546-O1546.
- . Blood, 89(8), 3064-3064.
- Von Willebrand factor and the Weibel-Palade body. THROMBOSIS AND HAEMOSTASIS, OC691-OC691.
- . Thrombosis and Haemostasis, 75(06), 959-964.
- . Thrombosis and Haemostasis, 76(05), 820-821.
- HLA class II profile: A determinant of factor VIII inhibitor development in severe haemophilia A.. BLOOD, 88(10), 1306-1306.
- The expression of von Willebrand factor (VWF) in endothelial cell lines ECV304 and EAhy926 following transfection with wild type (WT) and/or mutant VWF expression plasmids.. BLOOD, 88(10), 2951-2951.
- . Blood Coagulation & Fibrinolysis, 7(7), 734-734.
- . Blood, 88(5), 1700-1707.
- . Blood, 88(5), 1700-1707.
- The molecular basis of protein S deficiency in four unrelated kindred.. BRITISH JOURNAL OF HAEMATOLOGY, 93, 17-17.
- . Clinical Science, 90(s34), 22P-22P.
- . BLOOD, 87(8), 3255-3261.
- . Blood Coagulation & Fibrinolysis, 7(7), 672-677.
- . Thrombosis and Haemostasis, 74(01), 040-044.
- Molecular genetics and counselling in haemophilia.. Thromb Haemost, 74(1), 40-44.
- . British Journal of Haematology, 89(1), 152-156.
- . American Journal of Hematology, 48(2), 140-140.
- . British Journal of Haematology, 90(4), 884-891.
- . Haemophilia, 1(3), 159-164.
- . Haemophilia, 1(S1), 40-43.
- Identification of two protein S gene mutations in two kindred with deficiency of protein S and APC resistance. BLOOD, 86(10), 1426-1426.
- . Blood, 86(6), 2206-2212.
- . Blood Coagulation & Fibrinolysis, 6(6), 591-591.
- IDENTIFICATION OF MULTIPLE ELEMENTS REGULATING TRANSCRIPTION OF THE PROTEIN-S GENE. THROMBOSIS AND HAEMOSTASIS, 73(6), 1257-1257.
- PHENOTYPIC AND MOLECULAR CHARACTERIZATION OF TYPE-2N VON-WILLEBRAND DISEASE. THROMBOSIS AND HAEMOSTASIS, 73(6), 1169-1169.
- STEROID-HORMONE RESPONSIVE AND LIVER-SPECIFIC ELEMENTS REGULATE TRANSCRIPTION OF THE HUMAN PROTEIN-C GENE. THROMBOSIS AND HAEMOSTASIS, 73(6), 1255-1255.
- COMPARISON OF THE THROMBOTIC RISK IN GROUPS HETEROZYGOUS AND HOMOZYGOUS FOR THE FACTOR-V-G1691A MUTATION CONFERRING APC RESISTANCE. THROMBOSIS AND HAEMOSTASIS, 73(6), 1367-1367.
- . Blood Coagulation & Fibrinolysis, 6(2), 155-155.
- . Blood Coagulation & Fibrinolysis, 6(2), 178-178.
- DNA polymorphisms for carrier detection of hemophilia in Thailand.. Southeast Asian J Trop Med Public Health, 26 Suppl 1, 201-206.
- . Thrombosis and Haemostasis, 72(03), 475-476.
- . Thrombosis and Haemostasis, 72(06), 799-803.
- . British Journal of Haematology, 87(1), 215-217.
- . British Journal of Haematology, 88(1), 219-222.
- HEMOPHILIA-A - DATABASE OF NUCLEOTIDE SUBSTITUTIONS, DELETIONS, INSERTIONS AND REARRANGEMENTS OF THE FACTOR-VIII GENE, 2ND EDITION (VOL 22, PG 3511, 1994). NUCLEIC ACIDS RESEARCH, 22(22), 4850-4868.
- . Nucleic Acids Research, 22(22), 4851-4868.
- . The Lancet, 344(8923), 694-695.
- . Nucleic Acids Research, 22(17), 3511-3533.
- . The Lancet, 343(8893), 329-330.
- A CHROMOGENIC ASSAY FOR ACTIVATED PROTEIN-C (APC) RESISTANCE. BLOOD, 84(10), A84-A84.
- A STANDARD NOMENCLATURE FOR FACTOR-VIII AND FACTOR-IX GENE-MUTATIONS AND ASSOCIATED AMINO-ACID ALTERATIONS. THROMBOSIS AND HAEMOSTASIS, 72(3), 475-476.
- . Blood Coagulation & Fibrinolysis, 5(1), 29-36.
- . Thrombosis and Haemostasis, 69(03), 216-216.
- . British Journal of Haematology, 84(1), 101-105.
- . Human Molecular Genetics, 2(12), 2159-2161.
- Detection of carriers and prenatal diagnosis of bleeding disorders.. Southeast Asian Journal of Tropical Medicine and Public Health, 24 Suppl 1, 37-40.
- . Blood Coagulation & Fibrinolysis, 4(2), 313-344.
- MBO-I POLYMORPHISM IN THE VON-WILLEBRAND-FACTOR PSEUDOGENE. THROMBOSIS AND HAEMOSTASIS, 69(6), 1178-1178.
- BLOOM,ARTHUR,LESLIE - OBITUARY. THROMBOSIS AND HAEMOSTASIS, 69(3), 216-216.
- SINGLE-BASE CHANGES IN C/EBP BINDING-SITE WITHIN THE FACTOR-IX PROMOTER AND THEIR RELATIVE EFFECTS ON TRANSCRIPTION LEVELS. THROMBOSIS AND HAEMOSTASIS, 69(6), 767-767.
- TESTOSTERONE-INDUCED RECOVERY OF FACTOR-IX TRANSCRIPTION IN PATIENTS WITH THE HEMOPHILIA-B LEYDEN PHENOTYPE. THROMBOSIS AND HAEMOSTASIS, 69(6), 847-847.
- THE FACTOR-VII ARG-353 GLN POLYMORPHISM AS A PREDICTOR OF HIGH PLASMA FACTOR-VII LEVELS IN A NORMAL POPULATION. THROMBOSIS AND HAEMOSTASIS, 69(6), 624-624.
- Haemophilia: strategies for carrier detection and prenatal diagnosis.. Bulletin of the World Health Organization, 71(3-4), 429-458.
- . Thrombosis and Haemostasis, 67(02), 277-280.
- The relationship of HIV-1 viral sequences detected by the polymerase chain reaction in haemophilic patients to clinical and other markers of infection.. Clin Lab Haematol, 14(1), 1-7.
- . Seminars in Thrombosis and Hemostasis, 18(01), 1-10.
- . Vox Sanguinis, 61(3), 221-224.
- . Vox Sanguinis, 61(3), 221-224.
- . Nucleic Acids Research, 19(18), 4821-4833.
- . Blood, 78(1), 250-250.
- . Blood, 78(1), 250-250.
- . Nucleic Acids Research, 19(11), 3159-3159.
- The molecular biology of von Willebrand's disease.. Q J Med, 79(289), 381-389.
- . Blood, 77(7), 1476-1483.
- INHIBITOR DETECTION - ASSAYS, THEIR VARIATION, SIGNIFICANCE AND INTERPRETATION - IMMUNOCHEMISTRY OF FACTOR-VIII-C AND FACTOR-IX-C INHIBITORS - EPITOPES AND MECHANISM OF ACTION - DISCUSSION. BLOOD COAGULATION & FIBRINOLYSIS, 2, 17-20.
- FACTOR-IX INHIBITORS IN HEMOPHILIA-B PATIENTS, THEIR INCIDENCE AND PROSPECTS FOR DEVELOPMENT WITH HIGH-PURITY FACTOR-IX PRODUCTS - ANAMNESTIC RESPONSE FOLLOWING INFUSION OF PROTHROMBIN COMPLEX CONCENTRATES (PCC) AND ACTIVATED PROTHROMBIN COMPLEX CONCENTRATES (APCC) IN HEMOPHILIA-A PATIENTS WITH INHIBITORS - DISCUSSION. BLOOD COAGULATION & FIBRINOLYSIS, 2, 59-62.
- FACTOR-VIII INHIBITORS IN A HEMOPHILIC POPULATION TREATED WITH LOW AND HIGH-PURITY FVIII CONCENTRATES - DISCUSSION. BLOOD COAGULATION & FIBRINOLYSIS, 2, 25-30.
- . British Journal of Haematology, 75(2), 217-221.
- . British Journal of Haematology, 76(2), 242-249.
- . The Lancet, 336(8715), 638-639.
- . Blood, 76(3), 555-561.
- . Blood, 76(3), 555-561.
- . La Ricerca in Clinica e in Laboratorio, 20(3), 177-185.
- . Blood, 75(3), 654-661.
- . Blood, 75(3), 654-661.
- . British Journal of Haematology, 72(2), 208-215.
- . British Journal of Haematology, 71(1), 85-90.
- . British Journal of Haematology, 72(4), 556-560.
- . Journal of Clinical Pathology, 42(7), 673-676.
- . Clinical & Laboratory Haematology, 10(3), 295-306.
- . British Journal of Haematology, 70(1), 77-84.
- . Journal of Medical Genetics, 25(11), 779-780.
- . British Journal of Haematology, 66(3), 341-348.
- . Journal of Clinical Investigation, 79(3), 746-753.
- . British Journal of Haematology, 62(3), 557-565.
- . The Lancet, 327(8493), 1335-1336.
- . Thrombosis and Haemostasis, 53(01), 143-147.
- . BioEssays, 2(3), 110-113.
- . The Lancet, 326(8462), 1003-1004.
- . Clinical Science, 67(6), 561-567.
- . Thrombosis Research, 34(5), 379-387.
- . The Lancet, 323(8387), 1182-1182.
- . The Lancet, 323(8371), 242-243.
- . Thrombosis and Haemostasis, 50(03), 757-757.
- . Thrombosis and Haemostasis, 50(02), 509-512.
- . British Journal of Haematology, 53(1), 55-63.
- . British Journal of Haematology, 55(1), 27-36.
- . British Journal of Haematology, 53(4), 641-653.
- . British Journal of Haematology, 48(4), 651-660.
- . British Journal of Haematology, 48(4), 643-650.
- . Thrombosis Research, 23(1-2), 193-196.
- . Thrombosis Research, 22(1-2), 87-96.
- Factor VIII-related activities in therapeutic concentrates.. J Lab Clin Med, 97(3), 429-438.
- . Thrombosis and Haemostasis, 43(02), 167-168.
- . Clinical & Laboratory Haematology, 2(2), 121-128.
- . British Journal of Haematology, 45(3), 499-511.
- . The Lancet, 316(8202), 994-997.
- . British Journal of Haematology, 41(4), 585-596.
- . British Journal of Haematology, 42(2), 269-281.
- . The Lancet, 314(8143), 637-638.
- . Thrombosis Research, 15(3-4), 505-512.
- . Thrombosis Research, 16(5-6), 847-852.
- . The Lancet, 312(8095), 888-889.
- . Thrombosis Research, 12(5), 929-935.
- . The Lancet, 311(8062), 473-475.
- . Thrombosis Research, 11(1), 43-56.
- . Thrombosis Research, 10(1), 27-32.
- . The Lancet, 307(7949), 46-46.
- . British Journal of Haematology, 26(4), 669-677.
- . Thrombosis Research, 5(5), 585-599.
- Proceedings: Factor-VIII-related antigen in the human foetus and its synthesis in tissue culture.. Br J Haematol, 28(1), 143.
- . The Lancet, 304(7874), 222-223.
- . New England Journal of Medicine, 291(3), 113-117.
- . The Lancet, 303(7857), 576-576.
- . Thrombosis Research, 3(4), 389-404.
- . The Lancet, 302(7830), 674-675.
- . The Lancet, 301(7810), 1000-1001.
- . The Lancet, 301(7804), 661-662.
- . International Journal of Laboratory Hematology, 17(3), 264-266.
- . Arzneimittelforschung, 49(02), 163-165.
- . British Journal of Haematology, 77(4), 559-560.
- . QJM: An International Journal of Medicine.
Book chapters
- (pp. 204-215). Wiley
- (pp. 127-136). Wiley
- (pp. 137-146). Wiley
- , Principles of Molecular Medicine (pp. 209-217). Humana Press
- , Protides of the Biological Fluids (pp. 33-35). Elsevier
Conference proceedings
- EVALUATION OF THE VON WILLEBRAND FACTOR (VWF) INHIBITOR IN A LARGE COHORT OF EUROPEAN AND IRANIAN PATIENTS PREVIOUSLY DIAGNOSED WITH TYPE 3 VON WILLEBRAND DISEASE (VWD3) ENROLLED INTO THE 3WINTER-IPS PROJECT. HAEMATOLOGICA, Vol. 104 (pp 24-24)
- . Blood, Vol. 132(Supplement 1) (pp 2464-2464)
- . Blood, Vol. 132(Supplement 1) (pp 1180-1180)
- . Blood, Vol. 132(Supplement 1) (pp 2465-2465)
- . Blood, Vol. 132(Supplement 1) (pp 1184-1184)
- . Journal of Thrombosis and Haemostasis, Vol. 13(Suppl. 2) (pp 23-23), 20 June 2015 - 25 June 2015.
- . Journal of Thrombosis and Haemostasis, Vol. 13(Suppl. 2) (pp 251-251), 20 June 2015 - 25 June 2015.
- . Journal of Thrombosis and Haemostasis, Vol. 13(Suppl. 2) (pp 508-508), 20 June 2015 - 25 June 2015.
- . Journal of Thrombosis and Haemostasis, Vol. 13(Suppl. 2) (pp 505-505), 20 June 2015 - 25 June 2015.
- . Journal of Thrombosis and Haemostasis, Vol. 13(Suppl. 2) (pp 126-126), 20 June 2015 - 25 June 2015.
- Characterization and expression of an in-frame exon 33-34 deletion causing type 1 VWD. Blood, Vol. 124
- Re-evaluation of sequence variation in type 1 von Willebrand disease in the MCMDM-1VWD cohort. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 11 (pp 413-414)
- Investigation of the effect of CLEC4M on plasma von Willebrand factor level in the general population. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 11 (pp 552-553)
- Characterisation of large in-frame deletions contributing to type 1 VWD pathogenesis in the MCMDM-1VWD study. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 11 (pp 117-118)
- Previously missed mutations in the MCMDM-1VWD type 1 von Willebrand disease study. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 11 (pp 415-415)
- Characterisation of von Willebrand disease mutational spectrum in a Turkish patient cohort. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 9 (pp 914-914)
- Missing mutation in type 1 von Willebrand disease in the MCMDM-1 VWD study. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 9 (pp 914-914)
- Copy number variation is a significant contributor to type 1 VWD pathogenesis in the EU MCMDM-1VWD cohort. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 9 (pp 55-56)
- Investigation of the Role of Copy Number Variation In the Pathogenesis of Type 1 Von Willebrand Disease.. BLOOD, Vol. 116(21) (pp 913-913)
- FUT3 gene determining Lewis blood group antigen expression influences VWF:Ag levels in plasma. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 7 (pp 1147-1147)
- Associations between the von willebrand factor gene (VWF) variant C.2771G > A (P.R924Q), von willebrand factor antigen (VWF:Ag) and FVIII activity (FVIII:C) levels and its role as a risk factor for type 1 von willebrand disease (VWD). JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 7 (pp 11-11)
- Identification of three additional mutations in patients enrolled in the european study, molecular and clinical markers for the diagnosis and management of type 1 VWD (MCMDM-1VWD). JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 7 (pp 192-192)
- Identification of two novel P2Y12 ADP receptor gene defects in patients with type 1 von Willebrand disease. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 7 (pp 158-158)
- Use of in silico and in vitro analysis to identify VWF 5¢ regulatory elements. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 7 (pp 255-256)
- . Journal of Thrombosis and Haemostasis, Vol. 5
- . Blood, Vol. 110(11) (pp 714-714)
- . Blood, Vol. 104(11) (pp 4020-4020)
- Variable phenotypic penetrance of von Willebrand factor gene Y1584C heterozygosity in type 1 von Willebrand disease families and its association with enhanced in vitro susceptibility to ADAMTS 13 mediated proteolysis.. BLOOD, Vol. 102(11) (pp 311A-311A)
- Analysis of cosegregation of type 1 Von Willebrands disease phenotype and von Willebrand factor gene haplotypes in the European Multicenter MCMDM-1VWD study.. BLOOD, Vol. 102(11) (pp 90A-90A)
- Contribution of ABO blood group to type 1 von Willebrand disease in patients entered in the multicentre MCMDM-1VWD study.. BLOOD, Vol. 102(11) (pp 91A-91A)
- Mutational analysis in five families with type 1 von Willebrand disease. BLOOD, Vol. 100(11) (pp 69B-69B)
- Incidence and prognosis of c-kit and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias.. BLOOD, Vol. 100(11) (pp 746A-746A)
- . Thrombosis and Haemostasis, Vol. 84(08) (pp 160-174)
- . Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 20(7) (pp 1763-1768)
- Relapsing precursor B-ALL presenting as CD-10 positive isolated extramedullary lymphoma.. BLOOD, Vol. 94(10) (pp 219B-219B)
- Null alleles are not a common cause of type 1 vonWillebrand's disease. BRITISH JOURNAL OF HAEMATOLOGY, Vol. 102(1) (pp 15-15)
- Two unrelated families with different type 2N VWD mutations share a common splice site mutation.. BRITISH JOURNAL OF HAEMATOLOGY, Vol. 101 (pp 87-87)
- Mutations in the pro-peptide of VWF causing type 1 and type 3 VWD.. BRITISH JOURNAL OF HAEMATOLOGY, Vol. 101 (pp 67-67)
- Recombinate PUP mutation study: Relationship between factor VIII mutation and inhibitor development. BRITISH JOURNAL OF HAEMATOLOGY, Vol. 101 (pp 84-84)
- Mutations within the vWF gene resulting in type 1 and type 3 vWD in consanguineous families. THROMBOSIS AND HAEMOSTASIS (pp P2667-P2667)
- HLA class II profile: A determinant of inhibitor development in severe haemophilia A. THROMBOSIS AND HAEMOSTASIS (pp P2657-P2657)
- Mutation at Arg611 in the von Willebrand factor gene results in unclassifiable type 2 von Willebrand disease. THROMBOSIS AND HAEMOSTASIS (pp P2665-P2665)
- . Blood, Vol. 87(8) (pp 3255-3261)
- A RAPID AND COST-EFFECTIVE METHOD FOR ANALYSIS OF DINUCLEOTIDE REPEAT POLYMORPHISMS IN THE FACTOR-VIII GENE. THROMBOSIS AND HAEMOSTASIS, Vol. 73(6) (pp 1221-1221)
- The molecular biology of haemophilia. HEREDITARY DISEASES AND BLOOD TRANSFUSION, Vol. 30 (pp 3-9)
- Improved detection of the insertion/deletion polymorphism of the ACE gene and relationship to serum ACE activity in a normotensive U.K. population. British Journal of Clinical Pharmacology, Vol. 34(2) (pp 151)
- . Thrombosis and Haemostasis, 6 July 1987 - 10 July 1987.
- . Thrombosis and Haemostasis, 6 July 1987 - 10 July 1987.
- . Thrombosis and Haemostasis, 6 July 1987 - 10 July 1987.
- . Thrombosis and Haemostasis, 6 July 1987 - 10 July 1987.
- . Thrombosis and Haemostasis, 6 July 1987 - 10 July 1987.
- . Thrombosis and Haemostasis, 13 July 1981 - 17 July 1981.
- . Thrombosis and Haemostasis, 13 July 1981 - 17 July 1981.
- . Thrombosis and Haemostasis, 13 July 1981 - 17 July 1981.
- . Thrombosis and Haemostasis, 13 July 1981 - 17 July 1981.
- . Thrombosis and Haemostasis, 13 July 1981 - 17 July 1981.
- . Thrombosis and Haemostasis, 13 July 1981 - 17 July 1981.
- . Thrombosis and Haemostasis, 15 July 1979 - 20 July 1979.
- . Thrombosis and Haemostasis, 15 July 1979 - 20 July 1979.
- . Thrombosis and Haemostasis, 15 July 1979 - 20 July 1979.
- . Thrombosis and Haemostasis, 27 June 1977 - 1 July 1977.
Posters
- New insights into type 3 von Willebrand disease: the type 3 von Willebrand disease international registries and inhibitor prospective study (3WINTERS-IPS) project update.
- Teaching interests
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I teach at the postgraduate level.
- Professional activities and memberships
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I was a partner of the Health and Care Professions Council (HCPC) as a Clinical Scientist, I was also Registration Assessor for HCPC and for the Association of Clinical Scientists.
I am a past President of the International Society on Thrombosis and Haemostasis (ISTH Congress Birmingham 2003) and Chair of the ISTH Council (2006-2008). I am a past Council member of the British Society for Haemostasis and Thrombosis and the European Association for Haemophilia and Allied Disorders. I was also a member of the Education Committee of the European Haematology Association until 2012.