Professor Dilly Anumba
MBBS, FWACS, MD, FRCOG, LLM Medical Law
School of Medicine and Population Health
Professor of Obstetrics and Gynaecology
Chair of Obstetrics and Gynaecology
Consultant in Obstetrics and Gynaecology
Subspecialist in Fetomaternal Medicine
+44 114 215 9707
Full contact details
School of Medicine and Population Health
EU12
The Medical School
Beech Hill Road
Sheffield
S10 2RX
- Profile
-
For enquiries please contact - SMPH-West-Operational@sheffield.ac.uk
I joined the University of Sheffield in 2003 as Senior Clinical Lecturer and Honorary Consultant in Obstetrics and Fetal Medicine, following research and clinical training in Newcastle University and hospitals in Yorkshire and the Northern region.
I was accredited a specialist in Obstetrics and Gynaecology in 1999, and a subspecialist in Maternal and Fetal Medicine in 2001. Since 2003, I have maintained busy clinical (Obstetrics, Fetomaternal Medicine), research and teaching roles.
- Research interests
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I investigate the physiology of human parturition, particularly the role of immunity and inflammation in term/preterm labour and pregnancy complications such as hypertension, fetal growth restriction and stillbirth. I am also investigating new techniques to predict preterm birth by the detection of cervical remodelling changes as well as changes in the vaginal microbiome and metabolome.
I run specialist clinics in Prenatal Diagnosis and Fetal Therapy, Prematurity Prevention, and High-Risk Pregnancy, all of which have research spin-offs.
Current projects:
04/2018-2021 NIHR Global Health Grant Global Health Group for Preterm birth prevention and management (PRIME), £2million, Chief Investigator and Research Group Director.
• 07/2018-2021 EPSRC Grant, Nonlinear analysis of EIS and metabolite data for preterm birth management. Co-investigator with ZQ Lang £600°ì
• 04/2018-2021 NIHR Health Technology Assessment 16/16/06: COPE Randomised Control Trial, Management of postpartum haemorrhage, £1.8million. Co-investigator with Professor Andrew Weeks (Liverpool) et al
• 2017- 2020 NIHR Invention for Innovation (i4i) Scheme. Developing and testing a clinical grade magnetic impedance spectroscopy device for assessment of the cervix in pregnant women to predict preterm birth. £792,753.00. Chief and Principal Investigator, with Dr T Healey, Professor S Dixon and S Walters, Mrs. M Oppenshaw
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- . Journal of Global Health, 13.
- . BJOG: An International Journal of Obstetrics & Gynaecology, 130(S3), 113-123.
- . PLOS ONE, 18(4).
- . BMC Pregnancy and Childbirth, 23(1).
- . BMC Pregnancy and Childbirth, 22.
- . Sensors, 22(23).
- . Frontiers in Cell and Developmental Biology, 10.
- . Frontiers in Molecular Biosciences, 9.
- . BMC Pregnancy and Childbirth, 22(1).
- . Qualitative Health Research, 32(6), 1014-1026.
- . BMJ Open, 12(5).
- . BJOG: An International Journal of Obstetrics & Gynaecology, 129(7), 1211-1228.
- . Ultrasound in Obstetrics & Gynecology, 58(2), 293-302.
- . European Journal of Obstetrics & Gynecology and Reproductive Biology, 256, 523-524.
All publications
Books
- . Springer International Publishing.
- Preface.
- . Cambridge University Press.
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Journal articles
- . International Journal of Gynecology & Obstetrics.
- . The Journal of Maternal-Fetal & Neonatal Medicine, 38(1).
- . Cells, 14(14).
- . BJOG: An International Journal of Obstetrics & Gynaecology, 132(8), 1130-1138.
- . BMJ Open, 15(5).
- . npj Biofilms and Microbiomes, 11(1).
- . Cells, 14(4).
- . Acta Paediatrica, 114(3), 628-633.
- . PLOS ONE, 19(12).
- . Ultrasound in Obstetrics & Gynecology, 64(5), 635-650.
- . BMC Pregnancy and Childbirth, 24.
- . Placenta, 158, 23-37.
- . BMC Medicine, 22(1).
- . BMJ Open, 14(8).
- . Frontiers in Immunology, 15.
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- . European Journal of Obstetrics & Gynecology and Reproductive Biology, 300, 366-367.
- . International Journal of Gynecology & Obstetrics, 166(3), 1006-1013.
- . BJOG: An International Journal of Obstetrics & Gynaecology, 131(12), 1684-1693.
- . BMC Pregnancy and Childbirth, 24(1).
- . The Journal of Maternal-Fetal & Neonatal Medicine, 36(2).
- . Journal of Global Health, 13.
- . Frontiers in Global Women's Health, 4.
- . BJOG: An International Journal of Obstetrics & Gynaecology, 130(S3), 113-123.
- . PLOS ONE, 18(4).
- . Biomedical Signal Processing and Control, 80, 104345-104345.
- . BMC Pregnancy and Childbirth, 23(1).
- . Molecular Biology Reports, 50(4), 3035-3043.
- . BMC Pregnancy and Childbirth, 22.
- . Sensors, 22(23).
- . Frontiers in Cell and Developmental Biology, 10.
- . Frontiers in Molecular Biosciences, 9.
- . BMC Pregnancy and Childbirth, 22(1).
- . Reproduction and Fertility, 3(3), R177-R191.
- . Reproduction and Fertility, 3(3), L6-L8.
- . Qualitative Health Research, 32(6), 1014-1026.
- . BMJ Open, 12(5).
- . BJOG: An International Journal of Obstetrics & Gynaecology, 129(7), 1211-1228.
- . Current Microbiology, 79(3).
- . Journal of Antimicrobial Chemotherapy, 77(2), 283-289.
- . Reproductive Sciences, 29(3), 915-922.
- . Reproduction and Fertility, 2(4), L4-L6.
- . Global Public Health, 17(9), 2125-2138.
- . Placenta, 115, 27-36.
- . Ultrasound in Obstetrics & Gynecology, 58(2), 293-302.
- . European Journal of Obstetrics & Gynecology and Reproductive Biology, 264, 358-362.
- . AIDS, 35(5), 717-726.
- . International Journal for Equity in Health, 20(1).
- . PLoS ONE, 16(3).
- . Pediatric and Developmental Pathology, 24(3), 246-251.
- . Reproduction and Fertility, 2(1), R1-R12.
- . PLOS ONE, 16(1).
- . European Journal of Obstetrics & Gynecology and Reproductive Biology, 256, 523-524.
- . Placenta, 104, 81-88.
- . Journal of Clinical Pathology, 74(1), 10-18.
- . Frontiers in Immunology, 11.
- . PLoS ONE, 15(8).
- . British Journal of General Practice, 70(697), 417-418.
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- . British Journal of Nutrition, 123(10), 1127-1137.
- . Anaerobe, 62.
- . European Journal of Obstetrics & Gynecology and Reproductive Biology, 248, 128-132.
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- . International Urogynecology Journal, 31(3), 567-575.
- . PLOS ONE, 14(9).
- . Biomedical Optics Express, 10(8), 4190-4206.
- . Journal of Perinatology, 39(9), 1196-1203.
- . Journal of Obstetrics and Gynaecology, 39(8), 1081-1086.
- . Applied Spectroscopy Reviews, 54(4), 348-367.
- . Tropical Journal of Obstetrics and Gynaecology, 36(1), 1-1.
- . Frontiers in Endocrinology, 9.
- . Journal of Pregnancy, 2018.
- . Archives of Microbiology, 200(7), 1129-1133.
- . Journal of Biomaterials Applications, 33(2), 234-244.
- . The Obstetrician & Gynaecologist, 20(3), 201-203.
- . Frontiers in Medicine, 5.
- . Women and Birth, 31(3), 220-231.
- . Hypertension, 71(6), 1170-1177.
- . Journal of Reproductive Immunology, 126, 1-10.
- . PLoS ONE, 13(3).
- . Ultrasound in Obstetrics and Gynecology, 51(3), 387-395.
- . Circulation Journal, 81(11), 1654-1661.
- . Frontiers in Physiology, 8.
- . Journal of Reproductive Immunology, 121, 26-33.
- . Physiol Meas, 38(5), 729-744.
- . PLoS One, 12(3).
- . Lancet, 389(10068), 538-546.
- . Reproductive Biology and Endocrinology, 14.
- . Frontiers in Medicine, 3.
- . Hypertension, 68(4), 1049-1055.
- . Hypertension, 68(5), 1153-1159.
- . European Journal of Obstetrics & Gynecology and Reproductive Biology, 206, 105-113.
- . Obstetrics & Gynecology, 128(2), 245-252.
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- . Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 6(3), 150-151.
- . Metabolomics, 12(4).
- . Journal of Biomaterials Applications, 30(7), 995-1003.
- . BMC Pregnancy and Childbirth, 15.
- . British Journal of General Practice, 65(640), 574-574.
- . Ultrasound in Obstetrics and Gynecology, 46(2), 182-190.
- Fibrinogen altered the expression of inflammation, adhesion and angiogenic markers in pre-eclampsia monocytes co-cultured with vascular endothelial cells. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 122, 24-24.
- . Journal of Reproductive Immunology, 107, 43-51.
- . BMC Pregnancy Childbirth, 14, 207.
- . Arch Dis Child Fetal Neonatal Ed, 99 Suppl 1, A95.
- . Arch Dis Child Fetal Neonatal Ed, 99 Suppl 1, A113-A116.
- . Arch Dis Child Fetal Neonatal Ed, 99 Suppl 1, A109-A112.
- . J Reprod Immunol, 103, 23-28.
- . Circulation, 128(19), 2121-2131.
- . European Journal of Public Health, 23(suppl_1).
- . Best Pract Res Clin Obstet Gynaecol, 27(4), 537-548.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition, 98(Suppl 1), A19.2-A19.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition, 98(Suppl 1), A79.2-A79.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition, 98(Suppl 1), A78.1-A78.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition, 98(Suppl 1), A87.3-A87.
- . J Clin Virol, 57(2), 95-97.
- . PLoS One, 7(7), e42217.
- . Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2(3), 178-178.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition, 97(Suppl 1), A113.3-A113.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition, 97(Suppl 1), A117.4-A118.
- . J Transl Med, 10, 40.
- . PLoS One, 7(2), e30711.
- Monocyte Subpopulations in Pregnancy Complicated by Pre-Eclampsia Demonstrate a Pro-Inflammatory Phenotype and Altered Angiogenesis, Chemotaxis and Migration.. REPRODUCTIVE SCIENCES, 19(S3), 316A-316A.
- Monocyte subpopulations in pregnancy complicated by pre-eclampsia demonstrate a pro-inflammatory phenotype and upregulated expression of Toll-like receptors 2 and 4. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 119(6), e2-e2.
- . J EPIDEMIOL COMMUN H, 65.
- . BMC Womens Health, 11, 33.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition, 96(Suppl 1), Fa26.2-Fa26.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition, 96(Suppl 1), Fa63.1-Fa63.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition, 96(Suppl 1), Fa68.1-Fa68.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition, 96(Suppl 1), Fa76.1-Fa76.
- . Obstetric Anesthesia Digest, 31(2), 132-132.
- Cervical Electrical Impedance Spectroscopy May Predict Preterm Delivery in Women at Risk. REPROD SCI, 18(3), 301A-301A.
- The Contribution of Cervical Histology and Matrix Proteins to Tissue Electrical Resistivity Derived by Impedance Spectroscopy. REPROD SCI, 18(3), 273A-273A.
- . Qual Life Res, 20(7), 1011-1022.
- . J Obstet Gynaecol, 31(1), 78-80.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition, 95(Suppl 1), Fa95.4-Fa96.
- . Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 1, S45-S45.
- . Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 1, S45-S45.
- . Reprod Biol Endocrinol, 8, 62.
- . Reproductive Biology and Endocrinology, 8(1).
- . Hypertens Pregnancy, 29(2), 163-179.
- . BJOG, 117(3), 365-368.
- The effect of stress and anxiety associated with maternal prenatal diagnosis on feto-maternal attachment. JOURNAL OF PSYCHOSOMATIC OBSTETRICS AND GYNECOLOGY, 31, 86-86.
- . Pediatr Dev Pathol, 12(2), 96-102.
- . BMC Pregnancy Childbirth, 9, 40.
- . Eur J Obstet Gynecol Reprod Biol, 147(1), 41-45.
- . Biomed Eng Online, 8, 10.
- The role of cervical Electrical Impedance Spectroscopy in the prediction of the course and outcome of induced labour. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 116(10), 1410-1410.
- Serum Relaxin Levels Are Reduced in Pregnant Women with a History of Recurrent Miscarriage, and Correlate with Maternal Uterine Artery Doppler Indices. REPRODUCTIVE SCIENCES, 16(3), 255A-255A.
- Semi-quantitative analysis of TLR2 and TLR4 expression in the non-pregnant and pregnant cervix and the potential role of oestrogen. BJOG-INT J OBSTET GY, 115(1), 123-123.
- . Clin Dysmorphol, 17(1), 47-51.
- . J Obstet Gynaecol, 27(4), 430-431.
- . BJOG an International Journal of Obstetrics and Gynaecology, 114(7), 904-9e4.
- . Obstetrics Gynaecology and Reproductive Medicine, 17(6), 188-191.
- . Biomed Eng Online, 5, 62.
- . Eur J Obstet Gynecol Reprod Biol, 129(2), 145-149.
- . European Clinics in Obstetrics and Gynaecology, 1(4), 245-250.
- . Prenat Diagn, 26(3), 267-272.
- . BJOG, 113(1), 21-25.
- . Endocrinology, 146(11), 4994-5002.
- . Prenat Diagn, 25(3), 187-192.
- . Hum Reprod, 20(5), 1372-1378.
- . Current Obstetrics and Gynaecology, 15(5), 334-342.
- . Prenat Diagn, 25(1), 7-13.
- . Br J Clin Pharmacol, 53(3), 332-336.
- . Current Obstetrics & Gynaecology, 12(5), 286-292.
- . Current Obstetrics and Gynaecology, 12(5), 286-292.
- . Am J Obstet Gynecol, 185(2), 420.
- . Br J Clin Pharmacol, 47(2), 173-177.
- . Am J Physiol, 277(2), H848-H854.
- . Curr Opin Obstet Gynecol, 11(2), 149-156.
- . Am J Obstet Gynecol, 181(6), 1479-1484.
- Nitric oxide contributes to β2-adrenoceptor mediated vasodilatation in human forearm. Clinical Pharmacology and Therapeutics, 61(2), 230.
- . American Journal of Obstetrics and Gynecology, 176(1), S14-S14.
- Nitric oxide contributes to beta(2)-adrenoceptor mediated vasodilatation in human forearm.. CLINICAL PHARMACOLOGY & THERAPEUTICS, 61(2), PIV48-PIV48.
- . Journal of Obstetrics and Gynaecology, 14(6), 401-404.
- . Placenta and Reproductive Medicine, 2.
- . Womens Health, 14, 1-8.
- . Journal of Maternal-Fetal & Neonatal Medicine.
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Book chapters
- , Lecture Notes in Computer Science (pp. 85-97). Springer Nature Switzerland
- , Evidence Based Global Health Manual for Preterm Birth Risk Assessment (pp. 25-29). Springer International Publishing
- , Evidence Based Global Health Manual for Preterm Birth Risk Assessment (pp. 15-23). Springer International Publishing
- , Evidence Based Global Health Manual for Preterm Birth Risk Assessment (pp. 1-5). Springer International Publishing
- , Contemporary Obstetrics and Gynecology for Developing Countries (pp. 723-736). Springer International Publishing
- , Medicolegal Issues in Obstetrics and Gynaecology (pp. 85-87). Springer International Publishing
- , Medicolegal Issues in Obstetrics and Gynaecology (pp. 89-92). Springer International Publishing
- , Antenatal Disorders for the MRCOG and Beyond (pp. 63-80). Cambridge University Press
- , Antenatal Disorders for the MRCOG and Beyond (pp. 189-196). Cambridge University Press
- , Antenatal Disorders for the MRCOG and Beyond (pp. 1-12). Cambridge University Press
- , Antenatal Disorders for the MRCOG and Beyond (pp. 93-142). Cambridge University Press
- , Antenatal Disorders for the MRCOG and Beyond (pp. 13-26). Cambridge University Press
- , Antenatal Disorders for the MRCOG and Beyond (pp. 169-188). Cambridge University Press
- Cambridge University Press
- Cambridge University Press
- Cambridge University Press
- Cambridge University Press
- , Antenatal Disorders for the MRCOG and Beyond (pp. 159-168). Cambridge University Press
- Cambridge University Press
- , Antenatal Disorders for the MRCOG and Beyond (pp. 81-92). Cambridge University Press
- , Antenatal Disorders for the MRCOG and Beyond (pp. 149-158). Cambridge University Press
- , Antenatal Disorders for the MRCOG and Beyond (pp. 143-148). Cambridge University Press
- , Antenatal Disorders for the MRCOG and Beyond (pp. 27-38). Cambridge University Press
- , Antenatal Disorders for the MRCOG and Beyond (pp. 39-62). Cambridge University Press
- Antenatal Disorders for the MRCOG and Beyond Second Edition Preface, ANTENATAL DISORDERS FOR THE MRCOG AND BEYOND, 2ND EDITION (pp. IX-IX).
Conference proceedings
- Magnetic induction spectroscopy as a tool for detecting cervical remodelling to predict preterm birth. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 132 (pp 109-109)
- A case of periventricular cysts and corpus callosum agenesis identified in the third trimester following a growth scan in a low risk pregnancy. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 132 (pp 109-109)
- . Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2025, Vol. 13322 (pp 1332206). San Francisco, California, United States, 25 January 2025 - 25 January 2025.
- Optimising the potential of Tommys Clinical Decision Support Tool to reduce inequity. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 131 (pp 17-17)
- Tommy's Clinical Decision Support Tool: Lessons learned from a mixed-methods early adopter implementation evaluation. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 132 (pp 44-45)
- . Optical Coherence Imaging Techniques and Imaging in Scattering Media V, Vol. 12632 (pp 64-64). Munich, Germany, 25 June 2023 - 25 June 2023.
- . BJOG: An International Journal of Obstetrics & Gynaecology, Vol. 130(S2) (pp 101-109)
- Near-miss audit of SGA babies not detected during antenatal surveillance. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 130 (pp 209-210)
- Elevated Cervicovaginal Fluid Pro-Inflammatory Cytokines Predict Spontaneous Preterm Labour in Multiple Pregnancies. REPRODUCTIVE SCIENCES, Vol. 30 (pp 108A-109A)
- Metabolic Characteristics of Vaginal Dysbiosis Associated Bacteria: Mobiluncus curtisii and Lactobacillus iners. REPRODUCTIVE SCIENCES, Vol. 30 (pp 192A-192A)
- Cervicovaginal Fluid Markers of Inflammation and Extracellular Matrix Remodelling in Pregnant South African Women at High Risk of Spontaneous Preterm Birth. REPRODUCTIVE SCIENCES, Vol. 30 (pp 47A-47A)
- Ureaplasma parvum Infection Induces Inflammatory Changes in Vaginal Epithelial Cells Independent of Sialidase. REPRODUCTIVE SCIENCES, Vol. 30 (pp 190A-190A)
- Shotgun Metagenomic Sequencing Reveals Distinct Virome Profiles in Term and Preterm Human Placenta. REPRODUCTIVE SCIENCES, Vol. 30 (pp 161A-161A)
- Preterm birth clinic: Improved neonatal outcomes with better targeted interventions. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 130 (pp 175-175)
- Tommy's Clinical Decision Tool (Tommy's App): Early adopter implementation evaluation. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 130 (pp 101-102)
- Prediction of spontaneous preterm birth from routinely collected clinical data. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 130 (pp 209-210)
- High Stage and Grade of Maternal and Fetal Inflammatory Responses Are Associated with Low Placental CXCL10.. REPRODUCTIVE SCIENCES, Vol. 29(SUPPL 1) (pp 253-253)
- Increasing Cervicovaginal CXCL10 Across Mid-Trimester Predicted Women Destined to Deliver Preterm. REPRODUCTIVE SCIENCES, Vol. 29(SUPPL 1) (pp 200-201)
- Asymptomatic Women with Preterm Birth Have Distinct Cervicovaginal Metabolite Profile Across the Second Trimester. REPRODUCTIVE SCIENCES, Vol. 29(SUPPL 1) (pp 194-194)
- Metabolic Profiling of Gardenerella vaginalis: A Vaginal Dysbiosis and Preterm Birth-Associated Bacteria.. REPRODUCTIVE SCIENCES, Vol. 28(SUPPL 1) (pp 215A-216A)
- Differential Vaginal Lactobacillus Species Metabolism of Glucose, L- and D-lactate by13C-Nuclear Magnetic Resonance Spectroscopy.. REPRODUCTIVE SCIENCES, Vol. 28(SUPPL 1) (pp 216A-216A)
- Research priority-setting: prevention and treatment of pre-eclampsia/eclampsia in resource limited settings. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 128 (pp 99-100)
- Mid-Trimester Changes in Cervicovaginal Metabolites Are Distinct in Women with and without Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 28(SUPPL 1) (pp 114A-114A)
- Full Length Sequencing of Cervicovaginal Microbiota Associated with Spontaneous Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 28(SUPPL 1) (pp 213A-213A)
- Transcriptomic Analysis of Human Placenta Reveals a Distinct Gene Expression Pattern Associated with Dysregulated Apoptosis and Autophagy Leading to Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 28(SUPPL 1) (pp 274A-274A)
- Differential Metabolic Profiles of Lactobacillus Species and Preterm Birth-associated Bacteria.. REPRODUCTIVE SCIENCES, Vol. 27(SUPPL 1) (pp 122A-122A)
- . Diseases in the Breast and Reproductive System V (pp 2-2), 2 February 2019 - 7 February 2019.
- . Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII (pp 124-124), 2 February 2019 - 7 February 2019.
- Digital Twins as the Next Phase of Cyber-Physical Systems in Construction. Computing in Civil Engineering 2019 Data Sensing and Analytics Selected Papers from the ASCE International Conference on Computing in Civil Engineering 2019 (pp 256-264)
- Multivariate predictive model for infection/inflammation-associated preterm birth within 12 weeks of presentation with symptoms of preterm labour. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 126 (pp 132-132)
- Prediction of spontaneous preterm delivery within two weeks of presentation with symptoms of threatened preterm labour: utility of cervicovaginal fluid pro-inflammatory mediators. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 126 (pp 133-134)
- Discriminative Capacity of 1H-MRS Spectrum Binning for Preterm Delivery-Associated Lactobacilli-Dominated Vaginal Microbiota.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 212A-212A)
- A midtrimester combination of cervicovaginal fluid glutamate, acetate, and D-lactate identified asymptomatic low-risk women destined to deliver preterm: a prospective cohort study. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 126 (pp 126-126)
- The Role of Human Endothelial Colony Forming Cells in the Vascular Supply and Expansion of SKOV3-cells in a Murine Artificial Organ Xenograft Model.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 109A-110A)
- Prognostic Utility of Cervicovaginal Fluid Pro-Inflammatory Cytokines for Risk of Preterm Delivery within Two Weeks of Presentation with Symptoms of Threatened Preterm Labour.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 301A-302A)
- Infection/ Inflammation-Associated Preterm Delivery within 7-14 Days of Presentation with Symptoms of Preterm Labour: A Bimodal Predictive Model.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 301A-301A)
- Polarisation-Sensitive Optical Coherence Tomography as a Potential Tool for Assessing the Orientation of Collagen Fibres in the Human Cervix.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 128A-128A)
- Differential Cytokine and Metabolite Expression by Cervicovaginal Epithelial Cells Infected with Lactobacillus Crispatus and Preterm Birth-Associated Bacteria.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 212A-212A)
- . BJOG: An International Journal of Obstetrics and Gynaecology, Vol. 125(S2) (pp 108-109). Brighton, UK, 19 April 2018 - 19 April 2018.
- Combining cervicovaginal fluid metabolite and cervical electrical impedance spectroscopy assessments in mid-trimester improves prediction of preterm birth in asymptomatic pregnant women - towards multimodality screening. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 92-92)
- Vaginal epithelial cells co-cultured with Lactobacillus and anaerobes differentially express acetate and CXCL8. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 90-90)
- Cervical electrical impedance spectroscopy predicts preterm delivery in asymptomatic women - the ECCLIPPxâ„¢ studies. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 12-12)
- Towards "Multimodality Screening" for Preterm Birth - Cervicovaginal Fluid Metabolites May Enhance the Prediction of Preterm Birth by Cervical Electrical Impedance Spectroscopy. REPRODUCTIVE SCIENCES, Vol. 25 (pp 254A-254A)
- Women's Experiences of Incorporating Cervical Electrical Impedance Spectroscopy into Conventional Clinical Assessment of Risk of Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 25 (pp 186A-186A)
- Analysing Cervicovaginal Fluid Using Raman Spectroscopy as a Predictive Tool for Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 25 (pp 123A-123A)
- Electrical Impedance Spectroscopy Predicts Preterm Delivery in Asymptomatic Women.. REPRODUCTIVE SCIENCES, Vol. 25 (pp 63A-63A)
- Nonlinear Logistic Regression Analysis of Electrical Impedance Spectroscopy Data Improves the Accuracy of Prediction of Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 25 (pp 113A-113A)
- Cervicovaginal Epithelial Cells Differentially Express Acetate and CXCL8 in Co-Culture with Preterm Birth-Associated Bacteria and Protective Lactobacillus Species.. REPRODUCTIVE SCIENCES, Vol. 25 (pp 187A-187A)
- Prevalence and clinical outcome of patients presenting with reduced fetal movements (RFM). BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 73-73)
- Can antenatal risk factors predict fetal acidaemia at birth? A retrospective case control study. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 10-11)
- Cervical electrical impedance spectroscopy and cervicovaginal fluid metabolite assays may offer a multi-modal approach to improved screening for preterm birth in midtrimester. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 92-92)
- What factors militate against the antenatal detection of serious fetal anomalies in a UK tertiary antenatal care centre - a service review.. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 43-43)
- The Mid-Gestational Changes in Cervicovaginal RANTES and IL-1β Correlate with Fetal Fibronectin in Asymptomatic Pregnant Women and Are Predictive Markers of Inflammation-Associated Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 24 (pp 108A-109A)
- Do Small for Gestational Age (SGA) Fetuses Also Exhibit Circadian Changes in Fetal Heart Rate Parameters as Do Appropriate for Gestational Age (AGA) Fetuses?. REPRODUCTIVE SCIENCES, Vol. 24 (pp 200A-200A)
- Mid-Trimester Changes in Cervicovaginal Fluid Cytokine Profile of Asymptomatic Women as Early Indicators of Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 24 (pp 237A-237A)
- Predictive markers of inflammation-associated preterm birth in asymptomatic pregnant women: correlation of mid-gestational changes in cervicovaginal RANTES and IL-1β with fetal fibronectin. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 124 (pp 126-127)
- High Pelvic Floor Muscle Stiffness Measured by Vaginal Elastometry Is a Risk Factor for Delayed Second Stage of Labour, Instrumental Vaginal Delivery and Pelvic Floor Damage. REPRODUCTIVE SCIENCES, Vol. 24 (pp 124A-124A)
- Prognostic Capacity of Cervicovaginal Fluid Acetate-Glutamate Ratio for Risk of Preterm Delivery within Two Weeks of Presentation with Symptoms of Preterm Labor.. REPRODUCTIVE SCIENCES, Vol. 24 (pp 175A-175A)
- Decreased cervicovaginal fluid glutamate improves the predictive value of acetate for risk of preterm delivery within two weeks of presentation with threatened preterm labour. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 124 (pp 127-127)
- Mid-trimester changes in cervicovaginal fluid cytokine profile of asymptomatic women at risk of preterm birth correlate with gestational changes in prevalence of bacterial vaginosis - associated organisms. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 124 (pp 131-131)
- A quantitative longitudinal cohort study of mothers' and their partners' health and well-being in the first year postpartum. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 123 (pp 42-42)
- Does short-term variation of the fetal heart rate accurately predict fetal acidaemia?. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 123 (pp 43-43)
- The Effect of Relaxin-2 and Tissue Inhibitors of Matrix Metalloproteinase-2 (TIMP-2) on the Expression Levels of Matrix Metalloproteinase-2 (MMP-2) by Co-Incubation of Endometrial Stromal and Trophoblast Cell Lines.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 335A-335A)
- The Association of Cervicovaginal Fluid Metabolites at 20-22 Weeks Gestation with Quantitative Fetal Fibronectin, Ultrasound Cervical Length and Gestational Age at Delivery in Asymptomatic Pregnant Women.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 190A-191A)
- The Use of Second-Harmonic-Generation (SHG) to Assess the Impact of Menopause on the Orientation of Collagen Fibres in the Human Cervix.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 214A-214A)
- Prognostic Microbiomial and Metabolite Markers of Preterm Birth in Second Trimester Cervicovaginal Fluid from Women at Risk.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 128A-128A)
- Predicting Preterm Birth - The Performance of Ultrasound Cervical Length, Quantitative Fetal Fibronectin and Vaginal Fluid pH Differs by Risk of Preterm Birth and Symptoms of Preterm Labour. REPRODUCTIVE SCIENCES, Vol. 23 (pp 106A-106A)
- Elucidating Potential Metabolite Markers of Preterm Birth in Cervicovaginal Secretions By Nuclear Magnetic Resonance Spectroscopy. REPRODUCTIVE SCIENCES, Vol. 22 (pp 130A-130A)
- Using 3-D Models To Investigate Trophoblast-Endometrial Interactions In Vitro. REPRODUCTIVE SCIENCES, Vol. 22 (pp 226A-226A)
- Oestradiol Modulates Expression Levels of Toll-Like Receptor 2 and 4 in Human Ectocervical Epithelial Cells.. REPRODUCTIVE SCIENCES, Vol. 22 (pp 329A-329A)
- Assessing the Risk of Spontaneous Premature Birth By Electrical Impedance Spectroscopy of the Cervix: The ECCLIPPx Study.. REPRODUCTIVE SCIENCES, Vol. 22 (pp 331A-331A)
- Estrogen and hypoxia regulate expression of vascular endothelial growth factor and its receptors in uterine cervix of mice, which are localized in multiple cells of the tissue in mice and human. FASEB JOURNAL, Vol. 27
- Fibrinogen Attenuates sFlt-Induced Dys-Angiogenesis and Increases Vascular Adhesion Molecule Expression in Pre-Eclampsia.. REPRODUCTIVE SCIENCES, Vol. 20(S3) (pp 114A-114A)
- Monocytes of Women with Pre-Eclampsia Alter the Inflammatory Response of Human Vascular Endothelial Cells in Co-Culture. REPRODUCTIVE SCIENCES, Vol. 20(S3) (pp 114A-114A)
- . AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol. 208(1) (pp S345-S346)
- Expression Levels of Matrix Proteases and Their Inhibitors in the Serum of Pregnant Women: TIMP-2 and Relaxin Levels in 1st Trimester Are Potential Markers of Recurrent Pregnancy Loss.. REPRODUCTIVE SCIENCES, Vol. 17(3) (pp 72A-73A)
- Differential Expression of Tight Junction Proteins Occurs in the Pregnant Human Cervix. REPRODUCTIVE SCIENCES, Vol. 17(3) (pp 73A-73A)
- Gap Junction Protein Expression Is Down-Regulated during Pregnancy in the Human Cervix. REPRODUCTIVE SCIENCES, Vol. 17(3) (pp 73A-73A)
- Prostaglandins Induce Expression of Tight Junction but Not Gap Junction Proteins in the Pregnant Human Cervix. REPRODUCTIVE SCIENCES, Vol. 17(3) (pp 74A-74A)
- Identifying Regulatory Gene Networks in the Myometrium Governed by NF-kappa B. REPRODUCTIVE SCIENCES, Vol. 16(3) (pp 113A-113A)
- Expression of toll-like receptor 2 in human uterine cervical epithelial cells and their cytokine responses to toll2 ligands.. REPRODUCTIVE SCIENCES, Vol. 15(2) (pp 189A-190A)
- Semi-quantitative analysis of TLR2 and TLR4 expression in the non-pregnant and pregnant cervix and the potential role of oestrogen.. REPRODUCTIVE SCIENCES, Vol. 15(2) (pp 188A-188A)
- Analysis of 22q11 deletion in foetuses with increased nuchal translucency using the Vysis TUPLE1 probe. JOURNAL OF MEDICAL GENETICS, Vol. 44 (pp S110-S110)
- Temporal expression of the membrane-bound estrogen receptor, GPR30, in lower and upper segment human myometrium.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, Vol. 13(2) (pp 240A-240A)
- Subpopulations of cultured amniotic fluid cells display characteristics of pluripotent stem cells.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, Vol. 13(2) (pp 163A-163A)
- Mesenchymal stem cells derived from human amniotic fluid.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, Vol. 13(2) (pp 186A-186A)
- Lipopolysaccharide-induced ultra-structural changes and cytokine expression in human cervical tissue.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, Vol. 13(2) (pp 139A-139A)
- Placental mesenchymal dysplasia in association with Klinefelter syndrome. JOURNAL OF MEDICAL GENETICS, Vol. 41 (pp S48-S48)
- The role of prostanoids in the modulation of vascular tone in normal human pregnancy.. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 103(11) (pp 1170-1170)
- The role of nitric oxide in beta(2)-adrenoceptor-mediated vasodilatation in forearm arterial vasculature. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol. 42(5) (pp P652-P653)
- The role of nitric oxide in the modulation of vascular tone in normal pregnancy.. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 103(11) (pp 1169-1170)
Reports
Preprints
- , Cold Spring Harbor Laboratory.
- , Wiley.
- , Springer Science and Business Media LLC.
- , Research Square Platform LLC.
- , Research Square Platform LLC.
- , Springer Science and Business Media LLC.
- .
- Research group
-
Current Collaborators
- Professor (Emeritus) Brian Brown
- Dr Graham Stafford
- Dr Craig Murdoch
- Department of Medical Physics and Clinical Engineering STHFT
- Professor Adrian Porch
- Professor Zi-Qiang Lang, ACSE
- Professor Sheila MacNeil
PhD Students
- Dr Victoria Stern
- Ms Adannaya Achinanya
- Dr Brenda Narice
- Ms Megan Cavanagh
- Ms Kerry Paris
Post Doctoral Research Associates
- Dr Emmanuel Amabebe
- Dr Jill Tozer
- Dr Khundoker Akram
- Dr Shumona Salam
- Dr Bronwen Gillespie
- Ms Siobhan Gillespie
- Teaching interests
-
My main interest is postgraduate medical training and teaching.
I am Faculty of Medicine and South Yorkshire Director for Clinical Academic Training, and also Undergraduate Module Lead for Phase 3A Women´s Health, and Postgraduate Lead for the Pregnancy and Fetus Module of the MSc programme in Reproductive and Developmental Medicine.
I am Training Programme Supervisor for the Maternal and Fetal Medicine subspecialty training programme, Sheffield and serve on the South Yorkshire Foundation Training School Board, Clinical Academic Working Group, and Specialty Training Committee in Obstetrics and Gynaecology.
- Professional activities and memberships
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I am Vice Chair of the Academic Board of the Royal College of Obstetricians and Gynaecologists and serve on several other related organs. I am Lead Clinician of the Fetal Medicine Unit, Sheffield. I served on the NICE Medical Technologies Advisory Committee (MTAC).