Professor Alison Gartland

BSc (Hons), PhD

School of Medicine and Population Health

Professor of Bone and Cancer Biology

Professor Alison Gartland
Professor Alison Gartland
Profile picture of Professor Alison Gartland
a.gartland@sheffield.ac.uk
+44 114 215 9046

Full contact details

Professor Alison Gartland
School of Medicine and Population Health
FU25
The Medical School
Beech Hill Road
Sheffield
S10 2RX
Profile

For enquiries, please contact – SMPH-West-Operational@sheffield.ac.uk

I studied Biomedical Technology at Sheffield Hallam University and - following a period in industry - studied for my PhD at The University of Liverpool in Prof Jim Gallagher´s lab on the "Expression and functional significance of the P2X7 receptor in skeletal tissue".

I then moved to Montpellier, France where I was a Post-Doctoral Researcher at IGMM, CNRS in Bob Hipskind´s lab. Following this, I was a Senior Post-Doctoral Researcher in the Department of Cell Biology at the University of Massachusetts Medical School USA, in the late Prof Sandy Marks Jnr´s lab.

I joined the University of Sheffield in 2006 as a Lecturer in Bone Biology.

Research interests

My research interests are in P2 receptor signalling in musculoskeletal disease and cancer. The role of P2 purinoreceptor ligands (ATP and other nucleotides) as extracellular messengers is well established and there is now conclusive evidence, from my previous work and that of others, that extracellular nucleotides have a highly influential role in the bone microenvironment. In addition to their roles in bone, nucleotides and P2 receptor signalling have been shown to play a role in cancer.

Publications

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Journal articles

  • Bull EC, Singh A, Harden AM, Soanes K, Habash H, Toracchio L, Carrabotta M, Schreck C, Shah KM, Riestra PV , Chantoiseau M et al (2025) . Molecular Cancer, 24.
  • Coleman JC, Tattersall L, Yianni V, Knight L, Yu H, Hallett SR, Johnson P, Caetano AJ, Cosstick C, Ridley AJ , Gartland A et al (2024) . iScience, 27(4).
  • Roberts BC, Cheong VS, Oliviero S, Arredondo Carrera HM, Wang N, Gartland A & Dall'Ara E (2024) . Journal of Orthopaedic Research, 42(6), 1254-1266.
  • Tattersall L, Agrawal A, Adinolfi E & Gartland A (2023) . Purinergic Signalling, 19(4), 599-611.
  • Green D, Singh A, Tippett VL, Tattersall L, Shah KM, Siachisumo C, Ward NJ, Thomas P, Carter S, Jeys L , Sumathi V et al (2023) . Journal of Bone Oncology, 39.
  • Gartland A, Pasello M, Lézot F & Lamoureux F (2023) . Frontiers in Endocrinology, 14.
  • Song H, Arredondo Carrera HM, Sprules A, Ji Y, Zhang T, He J, Lawrence E, Gartland A, Luo J & Wang N (2023) . Cancer Communications, 43(3), 400-404.
  • Tippett VL, Tattersall L, Ab Latif NB, Shah KM, Lawson MA & Gartland A (2023) . Oncogene, 42(4), 259-277.
  • Pickering GAE, Felix-Ilemhenbhio F, Clark MJ, Kocsy K, Simpson J, Bellantuono I, Gartland A, Wilkinson JM, Hatzikotoulas K & Kiss-Toth E (2022) . International Journal of Molecular Sciences, 23(16).
  • Agrawal A, Ellegaard M, Haanes KA, Wang N, Gartland A, Ding M, Praetorius H & Jørgensen NR (2022) . Frontiers in Endocrinology, 13.
  • Tattersall L, Gagui DC, Tippett VL, Latif NBA, Shah KM & Gartland A (2022) . Frontiers in Bioscience-Landmark, 27(4).
  • Jin Y, Liu Q, Chen P, Zhao S, Jiang W, Wang F, Li P, Zhang Y, Lu W, Zhong TP , Ma X et al (2022) . Cell Discovery, 8(1).
  • Yue Z, Niu X, Yuan Z, Qin Q, Jiang W, He L, Gao J, Ding Y, Liu Y, Xu Z , Li Z et al (2022) . Journal of Clinical Investigation, 132(2).
  • Tattersall L, Shah KM, Lath DL, Singh A, Down JM, De Marchi E, Williamson A, Di Virgilio F, Heymann D, Adinolfi E , Fraser WD et al (2021) . Journal of Bone Oncology, 31.
  • Shah KM, Dunning MJ, Gartland A & Wilkinson JM (2021) . International Journal of Molecular Sciences, 22(10).
  • Roberts B, Cheong VS, Oliviero S, Carrera HA, Wang N, Gartland A & Dall'Ara E (2021) Oral Communications & Poster Abstracts. JBMR PLUS, 5.
  • He J, Zhou Y, Arredondo Carrera HM, Sprules A, Neagu R, Zarkesh SA, Eaton C, Luo J, Gartland A & Wang N (2020) . Cells, 9(11).
  • Agrawal A, Kruse LS, Vangsted AJ, Gartland A & Jørgensen NR (2020) . Cells, 9(11).
  • Roberts BC, Arredondo Carrera HM, Zanjani-pour S, Boudiffa M, Wang N, Gartland A & Dall’Ara E (2020) . Scientific Reports, 10(1).
  • Hatzikotoulas K, Pickering GAE, Clark MJ, Felix-Ilemhenbhio F, Kocsy K, Simpson J, MacInnes SJ, Koprulu M, Southam L, Bellantuono I , Baidžajevas K et al (2019) .
  • Barker HE, Chang J, Cox TR, Lang G, Bird D, Nicolau M, Evans HR, Gartland A & Erler JT (2019) . Cancer Research, 79(19), 5123-5123.
  • Erozenci LA, Wang N, Geldof AA, Mulder J, Jimenez CR, Moorselaar RJV, Gartland A, Vries TJD & Bijnsdorp IV (2018) . Cancer Research, 78(13_Supplement), 1085-1085.
  • Wang N, Agrawal A, Jørgensen NR & Gartland A (2018) . Scientific Reports, 8(1).
  • Ellegaard M, Agca C, Petersen S, Agrawal A, Kruse LS, Wang N, Gartland A, Jensen J-EB, Jørgensen NR & Agca Y (2017) . Purinergic Signalling.
  • Shah KM, Orton P, Mani N, Wilkinson JM & Gartland A (2017) . Journal of Orthopaedic Research, 35(8), 1716-1723.
  • Agca C, Syberg S, Jørgensen N, Gartland A & Agca Y (2016) . Cryobiology, 73(3), 416-416.
  • Dastgheib SA, Gartland A, Tabei SMB, Omrani GR & Teare MD (2016) . Frontiers in Endocrinology, 7.
  • Gartland A, Erler JT & Cox TR (2016) . Journal of Bone Oncology.
  • Proctor C & Gartland A (2016) . Frontiers in Endocrinology.
  • Varley I, Greeves JP, Sale C, Friedman E, Moran DS, Yanovich R, Wilson PJ, Gartland A, Hughes DC, Stellingwerff T , Ranson C et al (2016) . Purinergic Signalling, 12(1), 103-113.
  • Cox TR, Gartland A & Erler JT (2016) . Cancer Research, 76(2), 188-192.
  • Cox TR, Schoof EM, Gartland A, Erler JT & Linding R (2015) . Data in Brief, 5, 621-625.
  • Cox TR, Rumney RMH, Schoof EM, Perryman L, Høye AM, Agrawal A, Bird D, Ab Latif N, Forrest H, Evans HR , Huggins ID et al (2015) . NATURE, 522(7554), 106-110.
  • Shah KM, Wilkinson JM & Gartland A (2015) . Journal of Orthopaedic Research.
  • Agrawal A & Gartland A (2015) . Journal of Molecular Endocrinology, 54(2), R75-R88.
  • Shah KM, Quinn PD, Gartland A & Wilkinson JM (2015) . Journal of Orthopaedic Research, 33(1), 114-121.
  • Giuliani AL, Colognesi D, Ricco T, Roncato C, Capece M, Amoroso F, Wang QG, De Marchi E, Gartland A, Di Virgilio F & Adinolfi E (2014) . PLoS ONE, 9(9).
  • Gartland A & Hocking LJ (2014) . Curr Opin Pharmacol, 16, vii-ix.
  • Wang N & Gartland A (2014) . Curr Opin Pharmacol, 16, 122-126.
  • Wang N, Robaye B, Gossiel F, Boeynaems J-M & Gartland A (2014) . FASEB J, 28(5), 2249-2259.
  • Biver G, Wang N, Gartland A, Orriss I, Arnett TR, Boeynaems JM & Robaye B (2013) . Stem Cells, 31(12), 2747-2758.
  • Wang N & Gartland A (2013) . Purinergic Signalling, 9(3), 281-284.
  • Wang N, Rumney RMH, Yang L, Robaye B, Boeynaems J-M, Skerry TM & Gartland A (2013) . J Bone Miner Res, 28(6), 1446-1456.
  • Gheryani N, Coffelt SB, Gartland A, Rumney RMH, Kiss-Toth E, Lewis CE, Tozer GM, Greaves DR, Dear TN & Miller G (2013) . Genesis, 51(1), 41-49.
  • Syberg S, Petersen S, Beck Jensen JE, Gartland A, Teilmann J, Chessell I, Steinberg TH, Schwarz P & Jorgensen NR (2012) . Journal of Osteoporosis, 2012.
  • Rumney RMH, Wang N, Agrawal A & Gartland A (2012) . Front Endocrinol (Lausanne), 3, 116.
  • Cox TR, Gartland A & Erler JT (2012) . BoneKEy Reports, 1(5).
  • Gartland A, Skarratt KK, Hocking LJ, Parsons C, Stokes L, Jørgensen NR, Fraser WD, Reid DM, Gallagher JA & Wiley JS (2012) . Eur J Hum Genet, 20(5), 559-564.
  • Jørgensen NR, Husted LB, Skarratt KK, Stokes L, Tofteng CL, Kvist T, Jensen J-EB, Eiken P, Brixen K, Fuller S , Clifton-Bligh R et al (2012) Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures. European Journal of Human Genetics.
  • Gartland A (2012) . Wiley Interdisciplinary Reviews Membrane Transport and Signaling, 1(2), 221-227.
  • Wang N, Robaye B, Agrawal A, Skerry TM, Boeynaems J-M & Gartland A (2012) . Mol Endocrinol, 26(1), 142-152.
  • Gartland A, Orriss IR, Rumney RMH, Bond AP, Arnett T & Gallagher JA (2012) . Front Biosci (Landmark Ed), 17(1), 16-29.
  • Rumney RMH, Sunters A, Reilly GC & Gartland A (2012) . J Biomech, 45(3), 549-554.
  • Dillon JP, Waring-Green VJ, Taylor AM, Wilson PJM, Birch M, Gartland A & Gallagher JA (2012) . Methods Mol Biol, 816, 3-18.
  • Agrawal A, Gallagher JA & Gartland A (2012) . Methods Mol Biol, 806, 357-375.
  • Gartland A, Rumney RMH, Dillon JP & Gallagher JA (2012) . Methods Mol Biol, 806, 337-355.
  • Orriss IR, Wang N, Burnstock G, Arnett TR, Gartland A, Robaye B & Boeynaems J-M (2011) . Endocrinology, 152(10), 3706-3716.
  • Andrews RE, Shah KM, Wilkinson JM & Gartland A (2011) . Bone, 49(4), 717-723.
  • Orriss I, Syberg S, Wang N, Robaye B, Gartland A, Jorgensen NR, Arnett T & Boeynaems JM (2011) Bone phenotypes of P2 receptor knockout mice. Frontiers in Bioscience(S3), 1038-1046.
  • Wesselius A, Bours MJL, Agrawal A, Gartland A, Dagnelie PC, Schwarz P & Jorgensen NR (2011) . FRONT BIOSCI-LANDMRK, 16, 2572-2585.
  • Barker HE, Chang J, Cox TR, Lang G, Bird D, Nicolau M, Evans HR, Gartland A & Erler JT (2011) . Cancer Res, 71(5), 1561-1572.
  • Gartland A (2011) . PERSPECT PUBLIC HEAL, 131(1), 48-48.
  • Agrawal A, Buckley KA, Bowers K, Furber M, Gallagher JA & Gartland A (2010) . Purinergic Signalling, 6(3), 307-315.
  • Agrawal A, Buckley KA, Bowers K, Gaw A, Furber M, Gallagher JA & Gartland A (2010) The Effect of Different P2X(7) Receptor Antagonists on the Formation and Function of Human Osteoclast in vitro. PURINERG SIGNAL, 6(1), 139-140.
  • (2010) . Purinergic Signalling, 6(1), 125-144.
  • Gartland A, Mason-Savas A, Yang M, MacKay CA, Birnbaum MJ & Odgren PR (2009) . American Journal of Pathology, 175(6), 2668-2675.
  • Chan BY, Gartland A, Wilson PJM, Buckley KA, Dillon JP, Fraser WD & Gallagher JA (2007) . BONE, 40(1), 149-159.
  • Gartland A, Mechler J, Mason-Savas A, MacKay CA, Mailhot G, Marks SC & Odgren PR (2005) . Bone, 37(4), 530-544.
  • Devraj K, Bonassar LJ, MacKay CA, Mason-Savas A, Gartland A & Odgren PR (2004) . Connective Tissue Research, 45(1), 1-10.
  • Wise GE & Yao S (2003) . Critical Reviews in Eukaryotic Gene Expression, 13(2-4), 8-8.
  • Gartland A, Buckley KA, Hipskind RA, Perry MJ, Tobias JH, Buell G, Chessell I, Bowler WB & Gallagher JA (2003) Multinucleated osteoclast formation in vivo and in vitro by P2X(7) receptor-deficient mice. CRIT REV EUKAR GENE, 13(2-4), 243-253.
  • Gartland A, Buckley KA, Hipskind RA, Bowler WB & Gallagher JA (2003) P2 receptors in bone - Modulation of osteoclast formation and activity via P2X(7) activation. CRIT REV EUKAR GENE, 13(2-4), 237-242.
  • Gartland A, Buckley KA, Bowler WB & Gallagher JA (2003) . Calcif Tissue Int, 73(4), 361-369.
  • Odgren PR, Philbrick WM & Gartland A (2003) . Critical Reviews in Eukaryotic Gene Expression, 13(2-4), 14-14.
  • Wise GE & Yao S (2003) Expression of vascular endothelial growth factor in the dental follicle.. Crit Rev Eukaryot Gene Expr, 13(2-4), 173-180.
  • Buckley KA, Hipskind RA, Gartland A, Bowler WB & Gallagher JA (2002) . Bone, 31(5), 582-590.
  • Gartland A, Hipskind RA, Gallagher JA & Bowler WB (2001) . J Bone Miner Res, 16(5), 846-856.
  • Bowler WB, Buckley KA, Gartland A, Hipskind RA, Bilbe G & Gallagher JA (2001) . Bone, 28(5), 507-512.
  • Gartland A (2000) The role of the P2X7 receptor in bone cell formation.
  • Steinberg J, Shah KM, Gartland A, Zeggini E & Wilkinson JM () . Journal of Orthopaedic Research.
  • Gartland A () . IBMS BoneKEy, 10.

Book chapters

  • Tattersall L, Davison Z & Gartland A (2020) , Encyclopedia of Bone Biology (pp. 362-378). Elsevier
  • Buckley KA, Gartland A & Gallagher JA (2006) The role of purinergic signaling in the interactions between skeletal cells, Nucleotides and Regulation of Bone Cell Function (pp. 61-74).
  • Gartland A, Buckley KA, Dillon JP, Curran JM, Hunt JA & Gallagher JA (2005) (pp. 29-54).

Conference proceedings

  • He J, Zhou Y, Carrera HA, Wang N & Gartland A (2022) . Bone Reports, Vol. 16 (pp 101209-101209)
  • Sprules AR, Latif NB, Brown JE, Gartland A & Wang N (2021) . Cancer Research, Vol. 81(13_Supplement) (pp 2904-2904)
  • Gartland A (2021) Primordial signalling in prehistoric cancer. JOURNAL OF ANATOMY, Vol. 238(1) (pp 191-191)
  • Sprules AR, Latif NB, Brown JE, Gartland A & Wang N (2021) Mechanical loading induced osteogenic response does not interfere with the colonization of breast cancer in bone.. CANCER RESEARCH, Vol. 81(13)
  • Roberts B, Carrera HA, Pour SZ, Boudiffa M, Gartland A, Wang N & Dall'Ara E (2019) Longitudinal Effects of Combined Bone Anabolic Interventions on Ovariectomised Mice. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 34 (pp 258-259)
  • Tattersall L, De Marchi E, Williamson A, Di VF, Lawson MA, Adinolfi E & Gartland A (2018) P2X7R in primary bone cancer. PURINERGIC SIGNALLING, Vol. 14 (pp S13-S14)
  • Syberg S, Agrawal A, Petersen S, Jensen J-EB, Schwarz P, Gartland A, Boes M & Jorgensen N (2014) The P2X7 Antagonist AFC-5261 rescues Ovariectomy-induced Bone Loss in Mice.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 29 (pp S402-S403)
  • Dillon J, Wilson P, Gartland A, Hipskind R & Gallagher J (2013) A Novel Factor Derived From Resorbing Bone In Vitro Potently Stimulates C-Fos Expression In Breast Cancer Cells. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 28
  • Wang QG, Adinolfi E & Gartland A (2013) P2X7 Receptor Polymorphisms Modulate Osteoblast Cell Functions. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 28
  • Syberg S, Agca C, Wang N, Petersen S, Gartland A, Schwarz P, Jorgensen NR & Agca Y (2012) . BONE, Vol. 50 (pp S85-S86)
  • Syberg S, Agca C, Wang N, Petersen S, Gartland A, Schwarz P, Jorgensen NR & Agca Y (2012) . BONE, Vol. 50 (pp S67-S67)
  • Greeves J, Fraser W, Friedman E, Wilson P, Dillon J, Gartland A & Gallagher J (2012) . BONE, Vol. 50 (pp S108-S108)
  • Wang QG, Mohanty S, Bellantuono I & Gartland A (2012) TIBIAL PLATEAU BONE SURFACE ROUGHNESS - A POTENTIAL NEW EARLY MARKER TO DETECT ARTHRITIS?. OSTEOPOROSIS INTERNATIONAL, Vol. 23 (pp S574-S574)
  • Shah K, Quinn P, Wilkinson M & Gartland A (2012) SPECIATION AND DISTRIBUTION OF COBALT AND CHROMIUM IN OSTEOBLASTS AND OSTEOCLASTS USING MICROFOCUS X-RAY FLUORESCENCE AND X-RAY ABSORPTION NEAR-EDGE STRUCTURE. OSTEOPOROSIS INTERNATIONAL, Vol. 23 (pp S592-S592)
  • Agrawal A & Gartland A (2011) . BONE, Vol. 48 (pp S126-S126)
  • Wang N, Robaye B, Agrawal A, Reilly G, Boeynaems JM & Gartland A (2011) . BONE, Vol. 48 (pp S227-S227)
  • Evans HR, Ab Latif N, Cox TR, Bird D, Lang G, Erler JT & Gartland A (2011) . BONE, Vol. 48(1) (pp S21-S21)
  • Syberg S, Schwarz P, Petersen S, Jensen JEB, Steinberg TH, Gartland A, Chessell I & Jorgensen NR (2010) Bone status of P2X7 knockout mice in two different strains. PURINERG SIGNAL, Vol. 6 (pp 158-158)
  • Shah K, Patel V, Wang N & Gartland A (2010) The Effect of ATP on cancer cell proliferation in vitro -involvement of multiple P2X Receptors. PURINERG SIGNAL, Vol. 6(1) (pp 140-140)
  • Wang N, Rumney RMH, Agrawal A, Robaye B, Boeynaems JM & Gartland A (2010) Bone Phenotype of P2Y13 Receptor Knock-Out Mice. PURINERG SIGNAL, Vol. 6(1) (pp 144-144)
  • Rumney RMH, Wang N & Gartland A (2010) The role of P2X(7) receptors in ATP release from osteoblasts. PURINERG SIGNAL, Vol. 6(1) (pp 129-129)
  • Andrews R, Wilkinson J & Gartland A (2010) . BONE, Vol. 46 (pp S71-S71)
  • Orriss IR, Burnstock G, Gartland A & Arnett TR (2009) . BONE, Vol. 44 (pp S154-S154)
  • Gartland A, Skarratt KK, Hocking LJ, Stokes L, Clifton-Bligh R, Parsons C, Fraser WD, Reid DM, Wiley JS & Gallagher JA (2008) Loss of Function Polymorphisms in The P2X(7) Receptor Gene Are Associated with Accelerated Lumbar Spine Bone Loss in Postmenopausal Women.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 23 (pp S296-S296)
  • Gartland A, Buckley KA, Bowers K, Gaw A, Furber M & Gallagher JA (2008) A Novel Selective P2X(7) Receptor Antagonist Inhibits Human Osteoclast Formation in vitro.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 23 (pp S403-S403)
  • Orriss IR, Evans HR, Gartland A & Arnett TR (2008) Microct analysis of P2Y1 and P2Y2 receptor knockout mice demonstrates significant changes in bone phenotype. CALCIFIED TISSUE INT, Vol. 83(1) (pp 2-3)
  • Rumney RMH, Sittichokechaiwut A, Reilly G & Gartland A (2008) ATP release from osteoblasts is increased in response to mechanical loading by different amounts when grown in standard monolayer and novel 3D scaffolds. CALCIFIED TISSUE INT, Vol. 83(1) (pp 16-16)
  • Patel V, Rumney R, Wang N, Hipskind RH, Gallagher JA & Gartland A (2008) The effect of ATP, alone and in combination with EGF, on breast cancer cell survival. PURINERG SIGNAL, Vol. 4 (pp S205-S206)
  • Gartland A, Skarratt K, Hocking L, Clifton-Bligh R, Parsons C, Fraser W, Reid D, Wiley J & Gallagher J (2008) A polymorphism in the P2X7 receptor gene is associated with loss of lumbar spine bone mineral density in postmenopausal women. PURINERG SIGNAL, Vol. 4 (pp S172-S173)
  • Orriss I, Evans H, Arnett T & Gartland A (2008) MicroCT analysis of P2Y1 and P2Y2 receptor knockout mice demonstrates significant changes in bone phenotype. PURINERG SIGNAL, Vol. 4 (pp S176-S176)
  • Gallagher JA, Dillon JP, Kimani BM, Hayton MJ & Gartland A (2008) Regulation and mechanisms of ATP release from osteoblasts. PURINERG SIGNAL, Vol. 4 (pp S161-S161)
  • Rumney R, Wang N, Sittichokechaiwut A, Reilly G & Gartland A (2008) Different types of mechanical loading induce differentitial ATP release from osteoblasts grown on 3-dimensional scaffolds. PURINERG SIGNAL, Vol. 4 (pp S164-S165)
  • Rumney RMH, Sittichokechaiwut A, Reilly GC & Gartland A (2008) Cyclical compressive loading induces changes in cellular behaviour and ATP release from osteoblasts grown on 3-dimensional scaffolds. CALCIFIED TISSUE INT, Vol. 82 (pp S115-S116)
  • Gartland A, Skarrat KK, Hocking LJ, Clifton-Bligh R, Parsons C, Fraser WD, Reid DM, Gallagher JA & Wiley JS (2008) Novel association between a polymorphism in the P2X7 receptor gene and loss of lumbar spine bone mineral density in postmenopausal women. CALCIFIED TISSUE INT, Vol. 82 (pp S43-S43)
  • Gallaigher JA, Dillon JP, Wilson PM, Burrell HE, Hayton MJ, Fraser WD & Gartland A (2007) ATP is released from human osteoblasts by multiple mechanisms.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 22 (pp S146-S146)
  • Mwaura BK, Hayton MJ, Dillon JP, Burrell HE, Gallagher JA & Gartland A (2006) . BONE, Vol. 38(3) (pp S11-S11)
  • Gartland A, Hipskind RA, Fraser WD & Gallagher JA (2006) . BONE, Vol. 38(3) (pp S35-S35)
  • Buckley KA, Dillon JP, Chan BYY, Gartland A, Fraser WD & Gallagher JA (2006) . BONE, Vol. 38(3) (pp S10-S11)
  • (2006) Regulation of ATP release from human osteoblasts: A calcium dependant, exocytotic vesicular mechanism. CALCIFIED TISSUE INTERNATIONAL, Vol. 78 (pp S49-S49)
  • Chan BY, Buckley KA, Wilson PJ, Wherly N, Cheng Y, Dillon JP, Gartland A, Fraser WD & Gallagher JA (2005) Differential effect of PPAR agonists on human recombinant RANKL generated osteoclast culture in vitro. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 20(7) (pp 1303-1303)
  • Gartland A, Buckley KA, Dillon JP, Curran JM, Chan BYY, Fraser WD & Gallagher JA (2005) A biphasic pattern of osteoblast gene expression by differing concentrations of PTH 1-34. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 20(7) (pp 1308-1308)
  • Gartland A, Wilson PJ, Dillon JP, Chan BY, Buckley KA, Fraser WD & Gallagher JA (2005) ATP release and P2 receptor expression by human chondrocytes.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 20(7) (pp 1301-1301)
  • Chan BYY, Buckley KA, Wilson PJ, Wherly N, Cheng JY, Dillon JP, Gartland A, Fraser WD & Gallagher JA (2005) Effect of PPAR agonists, on human osteoclast formation and activity in vitro. BONE, Vol. 36 (pp S300-S301)
  • Mailhot G, Gartland A, Mason-Savas A, Mackay CA & Odgren PR (2005) Cellular and molecular characterization of primary rat chondrocytes differentiated in culture. BONE, Vol. 36 (pp S173-S173)
  • Gartland A, Fraser WD, Gallagher JA & Hipskind RA (2005) The effects of extracellular nucleotides on EGF-induced c-fos gene expression. BONE, Vol. 36 (pp S256-S256)
  • Chan BY, Buckley KA, Gartland A, Fraser WD & Gallagher JA (2005) Differential effect of PPAR agonists on generation of human osteoclasts in vitro. CLINICA CHIMICA ACTA, Vol. 355 (pp S32-S32)
  • Chan BY, Buckley KA, Gartland A, Fraser WD & Gallagher JA (2005) Differential effect of PPAR agonists on generation of human osteoclasts in vitro. CLINICA CHIMICA ACTA, Vol. 355 (pp S255-S255)
  • Gartland A, Mason-Savas A, MacKay C, Lee ER, Mort J, Odgren PR & Marks SC (2004) Abnormal septoclasts at the chondroosseous junction in the TL rat are normalised following CSF-1 treatment. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 19(6) (pp 1049-1049)
  • Odgren PR, Gartland A, Gartland A, Devraj K, Bonassar LJ, MacKay C & Mason-Savas A (2004) Osteopetrotic chondrodysplasia in the toothless (CSF-1null) rat: A paradigm for the role of osteoclastogenic factors as integrators of endochondral ossification. BONE, Vol. 34 (pp S38-S38)
  • Gartland A, Mason-Savas A, MacKay CA, Marks SC & Odgren PR (2003) Chondrocytes from the osteopetrotic mutation toothless (TL)/Csf-1 null rat differentiate in vitro. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 18(7) (pp 1370-1370)
  • Gartland A, Mason-Savas A, MacKay C, Lee ER, Mort J, Odgren PR & Marks SC (2003) CSF-1 treatment corrects septoclast abnormalities at the chondroosseous junction in the Toothless rat.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 18 (pp S111-S111)
  • Gartland A, Buckley KA, Hipskind RA, Perry MJ, Tobias JH, Buell G, Chessel I, Bowler WB & Gallagher JA (2002) P2X(7) receptor-deficient mice maintain the ability to form multinucleated) osteoclasts in vivo and in vitro. J BONE MINER RES, Vol. 17(7) (pp 1338-1338)
  • Gartland A, Mason-Savas A, MacKay CA, Marks SC & Odgren PR (2002) Chondrocytes, growth plates, and RANKL-induced signalling: Observations and implications of osteopetrotic mutations. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 17(7) (pp 1339-1339)
  • Gartland A, Gallagher JA & Bowler WB (2001) Blockade of P2X(7) receptors inhibits osteoclast fusion in vitro. BONE, Vol. 28(5) (pp S166-S167)
  • Bowler WB, Gartland A, Buckley KA, Golding SL & Gallagher JA (2000) ATP released into the extracellular environment by osteoblasts regulates differentiation and apoptosis of bone cells.. J BONE MINER RES, Vol. 15 (pp S476-S476)
  • Gartland A, Gallagher JA & Bowler WB (2000) Expression of the pore forming P2X(7) receptor by human rank ligand-generated osteoclasts and human osteoclastic cells in situ.. J BONE MINER RES, Vol. 15(6) (pp 1227-1227)
  • Shah KM () The Effect of ATP on cancer cell proliferation in vitro -involvement of multiple P2X Receptors. Purinergic Signalling, Vol. 6(1) (pp 140). Sheffield

Preprints

  • Coleman JC, Tattersall L, Yianni V, Knight L, Yu H, Hallett S, Johnson P, Caetano A, Cosstick C, Ridley A , Gartland A et al (2023) , Cold Spring Harbor Laboratory.
  • Roberts BC, Cheong VS, Oliviero S, Carrera HMA, Wang N, Gartland A & Dall’Ara E (2022) , Research Square Platform LLC.
  • Shah KM, Tattersall L, Hussain A, Macfarlane SC, Williamson A, Acosta-Martin AE, Erler JT, Ottewell PD & Gartland A (2022) , Cold Spring Harbor Laboratory.
  • Tattersall L, Shah KM, Lath DL, Singh A, Down JM, De Marchi E, Williamson A, Di Virgilio F, Heymann D, Adinolfi E , Fraser WD et al (2021) , Cold Spring Harbor Laboratory.
Research group

Current Collaborators

  • Professor Mark Wilkinson
  • Dr Dawn Teare
  • Dr Gaynor Miller
  • Dr Shelly Lawson

Postgraduate Students

  • Mr Luke Tattersall
Teaching interests

I am Chair of the Medical School Graduate Research Committee, I lecture on the undergraduate Medical Course as well as being the academic lead for the research Attachment SSC, I also run the Doctoral Development Programme module "Effective Presentation and Seminar Participation" MED605.

Professional activities and memberships

I am the Founder and President of the UK Purine Club, and member of the Bone Research Society, European Calcified Tissue Society, the International Bone and Mineral Society and the American Society for Bone and Mineral Research.