Professor Mark Strong
BSc MB ChB MPH MSc PhD MRCPCH FFPH FHEA CStat
School of Medicine and Population Health
Dean of the School of Medicine and Population Health
Professor of Public Health
  
  Full contact details
School of Medicine and Population Health
Western Bank Villa
300-302 Western Bank
Sheffield
S10 2TN
- Profile
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PA: Ellie Health (e.g.heath@sheffield.ac.uk)
I am Dean of the School of Medicine and Population Health (SMPH) and a Professor of Public Health.
I also hold an honorary clinical consultant contract with the at the Department of Health and Social Care.
 
- Research interests
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I have three related research interests that fall under the general banner of Uncertainty Quantification:
- How do we properly account for all relevant uncertainties when we build a computer model of a physical, biological or social system?
 - How do we (efficiently) compute value of information?
 - How do we work out the value of a computer model? How much should we pay to make a simple model more complex? When do we stop increasing the complexity of a model?
 
, and I have proposed an "internal" discrepancy-based method for managing model uncertainty. See , and that develops the idea of the 'Expected Value of Model Improvement'. The method is discussed in more detail in my .
We have proposed an efficient method for computing partial EVPI. This method works for any number of parameters of interest and requires only the PSA sample. See this in Medical Decision Making. R functions to implement the method can be downloaded .
Our online web calculator for partial EVPI, , is easy to use: Just upload your PSA sample and SAVI does the rest.
SAVI is also available as an R package from GitHub. This allows users to run the SAVI app on their own machine, and removes the need to transfer any data over the net. .
The partial EVPI method extends nicely to the computation of EVSI. See here for our .
Current and recent projects
- Calibrated Agent Simulations for Combined Analysis of Drinking Etiologies (): A US National Institutes of Health funded project on alcohol consumption (2016-2021). PI - .
 - Systems Science in Public Health and Health Economic Research (): A major UK Prevention Research Partnership funded project that will generate evidence for healthy public policy through a systems-science approach (2019-2024). PI - .
 
 
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- . Research Synthesis Methods, 15(4), 657-670.
 - . Health Econ, 32(7), 1603-1625.
 - . Med Decis Making, 43(5), 595-609.
 - . Annual Review of Statistics and Its Application, 9, 95-118.
 - . Medical Decision Making, 42(5), 612-625.
 - . Medical Decision Making, 42(2), 143-155.
 - . Medical decision making : an international journal of the Society for Medical Decision Making, 40(5), 669-679.
 - . Complexity, 2020, 1-20.
 - . Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23(6), 734-742.
 - . JASSS, 23(3), 1-25.
 - . Medical Decision Making, 40(3), 348-363.
 - . Medical Decision Making, 40(3), 314-326.
 - . Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23(3), 277-286.
 - . Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23(2), 139-150.
 - . Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23(2), 191-199.
 - . Medical Decision Making, 35(5), 570-583.
 - . PLoS One, 10(6).
 - . Medical Decision Making, 34(3), 311-326.
 - . SIAM/ASA Journal on Uncertainty Quantification, 2(1), 106-125.
 - . Journal of the Royal Statistical Society. Series C: Applied Statistics.
 
Conference proceedings
- . Proceedings of the Genetic and Evolutionary Computation Conference (pp 1356-1363)
 
Preprints
- , Cold Spring Harbor Laboratory.
 
All publications
Journal articles
- . Journal of Neurology, 272(8).
 - . Research Synthesis Methods, 16(3), 509-527.
 - . PharmacoEconomics, 43(4), 389-402.
 - . Value in Health, 28(1), 138-147.
 - HOW DOES UNPAID CAREGIVING AFFECT HEALTH-RELATED QUALITY OF LIFE? LONGITUDINAL ANALYSIS OF SF-6D FOR CARERS IN THE UK. VALUE IN HEALTH, 27(12).
 - . Value in Health, 27(12), S156-S156.
 - . Research Synthesis Methods, 15(4), 657-670.
 - . BMJ Public Health, 1(1), e000172-e000172.
 - . Mov Disord, 38(8), 1570-1572.
 - . Journal of Pediatrics, 263.
 - . Health Econ, 32(7), 1603-1625.
 - . Med Decis Making, 43(5), 595-609.
 - . Applied Health Economics and Health Policy, 21(2), 315-325.
 - . Annual Review of Statistics and Its Application, 9, 95-118.
 - . Medical Decision Making, 42(5), 612-625.
 - . Medical Decision Making, 42(2), 143-155.
 - . J Public Health (Oxf), 44(1), 184-191.
 - . International Journal of Environmental Research and Public Health, 18(21).
 - . Pharmacoeconomics, 39(12), 1373-1381.
 - . Appl Health Econ Health Policy, 19(5), 645-651.
 - . Systematic reviews, 10(1), 142.
 - . International Journal of Microsimulation, 13(2), 21-60.
 - . Medical decision making : an international journal of the Society for Medical Decision Making, 40(5), 669-679.
 - . Complexity, 2020, 1-20.
 - . Journal of Public Health United Kingdom, 42(2), 1-15.
 - . Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23(6), 734-742.
 - . JASSS, 23(3), 1-25.
 - . Medical Decision Making, 40(3), 348-363.
 - . Medical Decision Making, 40(3), 314-326.
 - . Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23(3), 277-286.
 - . Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23(2), 139-150.
 - . Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 23(2), 191-199.
 - . Archives of disease in childhood, 105(2), 155-159.
 - . Wellcome open research, 4, 174.
 - . Genetics in Medicine, 21(7), 1639-1643.
 - . The Lancet, 392(10159), 1995-2051.
 - . The Lancet, 392(10159), 1859-1922.
 - . The Lancet, 392(10159), 1789-1858.
 - . Addiction, 113(11), 2051-2059.
 - . PLoS ONE, 13(5).
 - . SAGE Open, 8(2).
 - . Journal of Epidemiology and Community Health , 72(6), 519-525.
 - . PLoS One, 13(4), e0194231.
 - . Health Technology Assessment Winchester England, 20(78), 407-424.
 - . JAMA Pediatrics, 172(2).
 - . BMC Pregnancy Childbirth, 18(1).
 - . American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 177(1), 35-39.
 - . PharmacoEconomics, 35(1), 1287-1296.
 - . The Lancet, 390(10106), e38-e38.
 - . Lancet, 390(10100), 1084-1150.
 - . The Lancet, 390(10100), 1151-1210.
 - . BMC Infectious Diseases, 17(1).
 - . The Lancet, 390(10091), 231-266.
 - . BMC Public Health, 17(1), 412-412.
 - . BMC Infectious Diseases, 17, 322-322.
 - . JMIR Research Protocols, 5(4).
 - . Journal of Public Health & Epidemiology, 8(10), 191-203.
 - . Lancet, 388(10053), 1813-1850.
 - . Health Technology Assessment, 20(78), 1-406.
 - . BMJ Open, 6.
 - . European Journal of Human Genetics, 24(10), 1515-1515.
 - . BMC Public Health, 16(649).
 - . Value in Health, 19(4), 505-509.
 - . Int J Epidemiol, 45(3), 707-712.
 - . European Journal of Human Genetics, 24, 1396-1402.
 - . BMJ Open, 6(4).
 - . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration .
 - . Health Technol Assess, 20(1), 1-198.
 - . BMJ Open, 5(11).
 - . Plos One, 10(8).
 - . Medical Decision Making, 35(5), 570-583.
 - . PLoS One, 10(6).
 - Encouraging breastfeeding: Financial incentives. Practising Midwife, 18(2), 18-21.
 - . Journal of Artificial Societies and Social Simulation, 18(3).
 - Scabies. BMJ Clinical Evidence, 2014.
 - . BMC Pregnancy and Childbirth, 14.
 - . International Journal of Obesity, 39, 535-541.
 - . BMC Public Health, 14, 444.
 - . Health Technol Assess, 18(33), 1-120.
 - . Medical Decision Making, 34(3), 311-326.
 - . Statistical Methods in Medical Research, 23(6), 552-571.
 - . Primary Care Respiratory Journal.
 - . SIAM/ASA Journal on Uncertainty Quantification, 2(1), 106-125.
 - . Spatial and Spatio-temporal Epidemiology.
 - . Annals of Surgical Innovation and Research, 14.
 - . Spatial and Spatio-temporal Epidemiology, 10, 27-28.
 - . Trials, 14(S1).
 - . BMC Med Res Methodol, 13, 103.
 - . Med Decis Making, 33(6), 755-766.
 - . The Lancet, 380, S70-S70.
 - . PLoS Curr, 4, e4f8606b742ef3.
 - . BMJ, 344, e3824-e3824.
 - . Spatial and Spatio-temporal Epidemiology.
 - . J Health Serv Res Policy, 17 Suppl 1, 31-39.
 - . Evidence-Based Child Health: A Cochrane Review Journal, 6(6), 1790-1862.
 - . Journal of Public Health, 33(4), 636-636.
 - . Journal of the Royal Statistical Society. Series C: Applied Statistics.
 - . Med Decis Making, 31(6), 839-852.
 - . International Journal of Infectious Diseases, 15(5), e294-e297.
 - . J Public Health (Oxf), 33(4), 536-542.
 - . Med Decis Making, 31(4), 571-581.
 - A poisoned chalice?. BMJ, 341, c4179.
 - Adverse effects of oseltamivir. Pediatria Catalana, 70(3), 131.
 - Adverse drug effects following oseltamivir mass treatment and prophylaxis in a school outbreak of 2009 pandemic influenza A(H1N1) in June 2009, Sheffield, United Kingdom.. Euro Surveill, 15(19), pii/19565.
 - . BMJ, 339, b3249.
 - . BMC Health Services Research, 9.
 - Scabies. BMJ Clinical Evidence, 2008.
 - . BRIT MED J, 337.
 - Treating Scabies Results From an Updated Cochrane Review Reply. ARCH DERMATOL, 144(12), 1640-1641.
 - Scabies.. BMJ Clin Evid, 2008.
 - . International Journal of Health Geographics, 6.
 - . BMC Family Practice, 8.
 - . COCHRANE DB SYST REV(3).
 - . BMJ, 335(7610), 60.
 - Scabies.. Clin Evid(15), 2284-2290.
 - . J PUBLIC HEALTH-UK, 28(3), 294-294.
 - . Int J Health Geogr, 5, 29.
 - . Journal of Public Health, 28(1), 39-42.
 - . J Public Health Med, 24(2), 120-122.
 - Observed total and live birth prevalence of Wolf-Hirschhorn Syndrome in England 2015-2020. Clinical Dysmorphology.
 - . Neurodegenerative Disease Management, 6(4).
 - . Journal of Public Health.
 
Book chapters
- , R for Health Technology Assessment (pp. 378-406). Chapman and Hall/CRC
 - , Value of Information for Healthcare Decision-Making (pp. 92-168). Chapman and Hall/CRC
 - , Bayesian Methods in Pharmaceutical Research (pp. 301-315). Chapman and Hall/CRC
 - (pp. 432-440). Wiley
 - Chapman and Hall/CRC
 
Conference proceedings
- DERIVING DECISION UNCERTAINTY ASSOCIATED WITH CALIBRATION TARGET DATA: A VALUE OF INFORMATION APPROACH. VALUE IN HEALTH, Vol. 27(12)
 - . British Association of Child and Adolescent Public Health (pp A93.1-A93)
 - AN EXTENDED SIMULATED TREATMENT COMPARISON APPROACH ACCOUNTING FOR UNOBSERVED CONFOUNDING IN INDIRECT COMPARISONS FOR SINGLE-ARM TRIALS. VALUE IN HEALTH, Vol. 25(12) (pp S358-S358)
 - EXPECTED VALUE OF SAMPLE INFORMATION FOR SURVIVAL DATA FROM ONGOING TRIALS. MEDICAL DECISION MAKING, Vol. 41(4) (pp E343-E344)
 - . Medical Decision Making, Vol. 40(1) (pp E63-E64). Portland, Oregon, 20 October 2019 - 20 October 2019.
 - . Medical Decision Making, Vol. 40(1) (pp E337-E338). Portland, Oregon, 20 October 2019 - 20 October 2019.
 - . Medical Decision Making, Vol. 40(1) (pp E1-E379)
 - . Value in Health, Vol. 22(Suppl 3) (pp S821-S821). Copenhagen, Denmark, 2 November 2019 - 2 November 2019.
 - . The Lancet, Vol. 394 (pp S22-S22)
 - . Proceedings of the Genetic and Evolutionary Computation Conference (pp 1356-1363)
 - PLATFORM FOR CALIBRATED, SYSTEM-BASED MODELS OF ALCOHOL USE DYNAMICS. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, Vol. 42 (pp 331A-331A)
 - . Lancet, Vol. 390 (pp S75-S75). London, UK, 24 November 2017 - 24 November 2017.
 - . Value in Health, Vol. 20(9) (pp A776-A776)
 - . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 87(Suppl 1) (pp A75.3-A75)
 - . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 87(Suppl 1) (pp A59.2-A59)
 - . Value in Health, Vol. 18(7) (pp A343-A343)
 - . Value Health, Vol. 18(7) (pp A725-A726). Milan, Italy, 7 November 2015 - 7 November 2015.
 - . European Journal of Public Health, Vol. 25(Supplement 3) (pp 207-208). Milan, Italy , 14 October 2015 - 14 October 2015.
 - . The Lancet, Vol. 384 (pp S5-S5)
 - . Value in Health, Vol. 17(7) (pp A584-A584)
 - . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 85(Suppl 1) (pp A80-A81)
 - Views on the acceptability of financial incentives for breastfeeding: a qualitative study. LANCET, Vol. 382 (pp 103-103)
 
Reports
Posters
- Modelling recurrent event data: a comparison of the Cox proportional hazards model and three of its extensions to estimate the risk of recurrent healthcare-associated infections in critically ill patients.
 - A Framework for the Economic Evaluation of Sequential Therapies for Chronic Conditions (2014). ISPOR.
 - Understanding public health systems: a participatory systematic review and systems infographic.
 - Early Years Policy in the UK - from the child’s perspective.
 
Other
- . The Lancet, 394(10216), 2242-2242.
 - . European Journal of Human Genetics, 25(11), 1290-1290.
 
Preprints
- , Cold Spring Harbor Laboratory.
 - , Center for Open Science.
 - , arXiv.
 - Calibration and Validation of the Microsimulation Model in Cancer of the Bowel (MiMiC-Bowel), an Individual Patient Simulation Model for Investigation of the Cost-effectiveness of Personalised Screening and Surveillance Strategies.
 - , Springer Science and Business Media LLC.
 - , Cold Spring Harbor Laboratory.
 - , arXiv.
 - , arXiv.
 
 
- Research group
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PhD students
 
- Teaching interests
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I teach on the Master in Public Health (MPH) course, the MSc in Health Economics and Decision Modelling course, and the medical undergraduate MB ChB degree. I also support registrars on the who are taking the DFPH exam.
PhD opportunities
I welcome PhD applications at any time. You are welcome to email me to discuss an idea before making an application. I supervise students who are interested in the topics of Value of Information and Uncertainty Quantification in health economic decision making.
 
Links