Dr Dawn Walker

School of Computer Science

Senior Lecturer

School Student Recruitment Lead

Member of the Complex Systems Modelling research group

Dawn Walker headshot
Profile picture of Dawn Walker headshot
d.c.walker@sheffield.ac.uk
+44 114 222 1914
Regent Court (DCS)

Full contact details

Dr Dawn Walker
School of Computer Science
Regent Court (DCS)
211 Portobello
Sheffield
S1 4DP
Profile

Dr Dawn Walker is a senior lecturer in the Computational Biology Group in the Department of Computer Science. Her primary research interest is the use of individual-based models to understand the function and structure of biological tissues.

She is also interested in multi-scale and multi-paradigm models in biology and medicine, and the use of bioelectric properties of epithelial tissues in early cancer diagnosis.

Research interests
  • Agent (individual) based Modelling in predicting emergent properties of biological tissues
  • Multiscale Modelling in biological and biomedical applications
  • Electrical Impedance Spectroscopy (EIS) for the diagnosis of early cancerous changes in epithelial tissues
Publications

Journal articles

  • Lin Z, Lang Z-Q, Guo L, Walker DC, Matella M, Wang M & Murdoch C (2025) . Scientific Reports, 15.
  • Wertheim KY, Chisholm R, Richmond P & Walker D (2024) . PLOS Computational Biology, 20(12).
  • Borau C, Chisholm R, Richmond P & Walker D (2024) . Computers in Biology and Medicine, 179.
  • Matella M, Hunter K, Balasubramanian S & Walker D (2024) . Sensors, 24(7).
  • Matella M, Hunter K, Balasubramanian S & Walker DC (2024) . IEEE Open Journal of Engineering in Medicine and Biology, 5, 661-669.
  • Borau C, Wertheim KY, Hervas-Raluy S, Sainz-DeMena D, Walker D, Chisholm R, Richmond P, Varella V, Viceconti M, Montero A , Gregori-Puigjan矇 E et al (2023) . Computer Methods and Programs in Biomedicine, 241.
  • Italia M, Wertheim KY, Taschner-Mandl S, Walker D & Dercole F (2023) . Cancers, 15(7).
  • Mason AS, Varley CL, Foody OM, Li X, Skinner K, Walker D, Larson TR, Wakamatsu D, Baker SC & Southgate J (2022) . International Journal of Molecular Sciences, 23(19).
  • Heath JP, Hunter KD, Murdoch C & Walker DC (2022) . Sensors, 22(15).
  • Kondylakis H, Ciarrocchi E, Cerda-Alberich L, Chouvarda I, Fromont LA, Garcia-Aznar JM, Kalokyri V, Kosvyra A, Walker D, Yang G & Neri E (2022) . European Radiology Experimental, 6(1).
  • de Melo Quintela B, Hervas-Raluy S, Garcia-Aznar JM, Walker D, Wertheim KY & Viceconti M (2022) . Journal of Theoretical Biology, 547.
  • Mart穩-Bonmat穩 L, Alberich-Bayarri , Ladenstein R, Blanquer I, Segrelles JD, Cerd獺-Alberich L, Gkontra P, Hero B, Garc穩a-Aznar JM, Keim D , Jentner W et al (2020) . European Radiology Experimental, 4(1).
  • Ingham-Dempster TA, Rosser R, Corfe BM & Walker DC (2020) . Journal of Computational Science, 41.
  • Viceconti M, Bna S, Tartarini D, Sfakianakis S, Grogan J, Walker D, Gamble S, Testi D & CHIC Project Consortium (2018) . Journal of Computational Science, 25, 101-114.
  • Ingham Dempster T, Corfe BM & Walker DC (2018) . Journal of Computational Science, 24, 125-131.
  • Ingham Dempster T, Walker DC & Corfe BM (2017) . Royal Society Open Science, 4(4), 160858-160858.
  • Eze PU, Walker DC & Achumba IE (2016) Constructive Initialization of a Genetic Algorithm for the Solution of a Highly Constrained Departmental Timetabling Problem. International Journal of Soft Computing and Engineering, 6(4), 18-25.
  • Zhang Z, Bedder M, Smith SL, Walker D, Shabir S & Southgate J (2016) . Biosystems, 146, 110-121.
  • Appleby PA, Shabir S, Southgate J & Walker D (2015) . Interface, 12(105).
  • Appleby PA, Shabir S, Southgate J & Walker D (2013) . J R Soc Interface, 10(86), 20130487.
  • Shabir S, Cross W, Kirkwood LA, Pearson JF, Appleby PA, Walker D, Eardley I & Southgate J (2013) . American Journal of Physiology Renal Physiology, 305(3), F396-F406.
  • Khodabakhshi G, Walker D, Scutt A, Way L, Cowie RM & Hose DR (2013) . Journal of Microscopy, 249(3), 195-205.
  • Walker DC & Southgate J (2013) . J R Soc Interface, 10(78), 20120703.
  • Burkitt M, Walker D, Romano DM & Fazeli A (2012) . IEEE/ACM Transactions on Computational Biology and Bioinformatics (ACM), 9(3), 643-654.
  • Burkitt M, Walker D, Romano DM & Fazeli A (2012) . Theriogenology, 77(4), 703-716.
  • Burkitt M, Walker D, Romano DM & Fazeli A (2011) . Reproduction Fertility and Development, 23(8), 976-989.
  • Halliday I, Atherton M, Care CM, Collins MW, Evans D, Evans PC, Hose DR, Khir AW, K繹nig CS, Krams R , Lawford PV et al (2011) . Medical Engineering and Physics, 33(7), 840-848.
  • Caiazzo A, Evans D, Falcone J-L, Hegewald J, Lorenz E, Stahl B, Wang D, Bernsdorf J, Chopard B, Gunn J , Hose R et al (2011) A Complex Automata approach for in-stent restenosis: Two-dimensional multiscale modelling and simulations. Journal of Computational Science.
  • Halliday I, Atherton M, Care CM, Collins MW, Evans D, Evans PC, Hose DR, Khir AW, K繹nig CS, Krams R , Lawford PV et al (2011) . Med Eng Phys, 33(7), 840-848.
  • Georgopoulos NT, Kirkwood LA, Walker DC & Southgate J (2010) . PLoS ONE, 5(10).
  • Richmond P, Walker D, Coakley S & Romano D (2010) . Brief Bioinform, 11(3), 334-347.
  • Walker DC, Georgopoulos NT & Southgate J (2010) . J Theor Biol, 262(3), 425-440.
  • Fazeli A, Burkitt M, Walker D & Romano DM (2009) . Biology of Reproduction, 81(Suppl_1), 299-299.
  • Walker DC & Southgate J (2009) . Brief Bioinform, 10(4), 450-461.
  • Walker DC, Georgopoulos NT & Southgate J (2008) . BMC Syst Biol, 2, 102.
  • Lawford PV, Ventikos Y, Khir AW, Atherton M, Evans D, Hose DR, Care CM, Watton PN, Halliday I, Walker DC , Hollis AP et al (2008) . Biomed Pharmacother, 62(8), 530-535.
  • Evans DJW, Lawford PV, Gunn J, Walker D, Hose DR, Smallwood RH, Chopard B, Krafczyk M, Bernsdorf J & Hoekstra A (2008) . Philos Trans A Math Phys Eng Sci, 366(1879), 3343-3360.
  • Evans DJW, Hoekstra A, Gunn J, Walker D, Hose DR, Smallwood RH, Chopard B, Krafczyk M, Bernsdorf J & Lawford PV (2008) . Journal of Biomechanics, 41, S482-S482.
  • Balasubramani L, Healey J, Walker D, Brown BH & Tidy JA (2008) Epitheliometer: a real time impedance device for the detection of high grade cervical intraepithelial neoplasia. BJOG-INT J OBSTET GY, 115(1), 118-118.
  • Ateh DD, Waterworth A, Walker D, Brown BH, Navsaria H & Vadgama P (2007) . J BIOMED MATER RES A, 83A(2), 391-400.
  • Gandhi SV, Walker DC, Brown BH & Anumba DOC (2006) . Biomed Eng Online, 5, 62.
  • Walker D, Sun T, MacNeil S & Smallwood R (2006) . Tissue Eng, 12(8), 2301-2309.
  • Walker D, Wood S, Southgate J, Holcombe M & Smallwood R (2006) . J Theor Biol, 242(3), 774-789.
  • Gonz獺lez-Correa CA, Brown BH, Smallwood RH, Walker DC & Bardhan KD (2005) . Physiol Meas, 26(2), S39-S47.
  • Walker DC, Smallwood RH, Keshtar A, Wilkinson BA, Hamdy FC & Lee JA (2005) . Physiol Meas, 26(3), 251-268.
  • Walker DC, Hill G, Wood SM, Smallwood RH & Southgate J (2004) . IEEE Trans Nanobioscience, 3(3), 153-163.
  • Smallwood RH, Holcombe WML & Walker DC (2004) . J Mol Histol, 35(7), 659-665.
  • Walker DC, Southgate J, Hill G, Holcombe M, Hose DR, Wood SM, Mac Neil S & Smallwood RH (2004) . Biosystems, 76(1-3), 89-100.
  • Jones DM, Smallwood RH, Hose DR, Brown BH & Walker DC (2003) . Physiol Meas, 24(2), 605-623.
  • Walker DC, Brown BH, Blackett AD, Tidy J & Smallwood RH (2003) . Physiol Meas, 24(1), 121-135.
  • Walker DC, Brown BH, Smallwood RH, Hose DR & Jones DM (2002) . Physiol Meas, 23(1), 159-168.
  • Walker DC, Brown BH, Hose DR & Smallwood RH (2000) Modelling the electrical impedivity of normal and premalignant cervical tissue. ELECTRON LETT, 36(19), 1603-1604.
  • Walker D, Sun T, MacNeil S & Smallwood R () . Tissue Engineering, 0(0), 060913044658037-060913044658037.

Conference proceedings

  • Matella M, Walker DC & Hunter K (2023) . 2023 IEEE International Symposium on Medical Measurements and Applications (MeMeA) (pp 1-6), 14 June 2023 - 16 June 2023.
  • Zhang Z, Bedder M, Smith SL, Walker D, Shabir S & Southgate J (2015) . Information Processing in Cells and Tissues, Vol. 9303 (pp 185-194)
  • Appleby PA, Shabir S, Southgate J & Walker D (2013) . IC-MSQUARE 2012: INTERNATIONAL CONFERENCE ON MATHEMATICAL MODELLING IN PHYSICAL SCIENCES, Vol. 410
  • Burkitt M, Walker D, Romano DM & Fazeli A (2011) . Proceedings of the 9th International Conference on Computational Methods in Systems Biology Cmsb 11 (pp 141-149)
  • Burkitt M, Walker D, Romano DM & Fazeli A (2010) . Proceedings of the 9th Int Workshop on Parallel and Distributed Methods in Verification Pdmc 2010 Joint with the 2nd Int Workshop on High Performance Computational Systems Biology Hibi 2010 (pp 78-87)
  • Burkitt M, Romano DM, Walker DC & Fazeli A (2010) 3D Modelling of Complex Biological Structures: The Oviduct.. TPCG (pp 255-262)
  • Burkitt M, Romano DM, Walker D & Fazeli A (2010) Using computational systems biology to investigate sperm navigation and transport in the female reproductive tract. Systems Biology in Maternal Communication with Gametes and Embryo. Opatija, Croatia, 9 May 2010 - 13 May 2010.
  • Caiazzo A, Evans D, Falcone JL, Hegewald J, Lorenz E, Stahl B, Wang D, Bernsdorf J, Chopard B, Gunn J , Hose R et al (2009) . Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, Vol. 5544 LNCS(PART 1) (pp 705-714)
  • Evans DJW, Caiazzo A, Falcone JL, Hegewald J, Lorenz E, Stahl B, Wang D, Bernsdorf J, Chopard B, Gunn J , Walker D et al (2009) COAST: Modelling Restenosis and Stent Based Therapies. INTERNATIONAL CONFERENCE ON ADVANCEMENTS OF MEDICINE AND HEALTH CARE THROUGH TECHNOLOGY, Vol. 26 (pp 319-322)
  • Fazeli A, Burkitt M, Walker D & Romano DM (2009) The Virtual Oviduct: An Essential Tool for the Application of Computational Biology Approaches to Investigation of Maternal Interaction with Gametes and Embryo. BIOLOGY OF REPRODUCTION (pp 115-115)
  • Milnes P, Southgate J, Walker DC & Jin ZM (2007) Finite element modelling of a cell stressing device. TISSUE ENGINEERING, Vol. 13(7) (pp 1697-1698)
  • Tartarini D, Viceconti M, Gruel N, Duan K & Walker DC () . In Silico Oncology and Cancer Investigation (IARWISOCI), 2014 6th International Advanced Research Workshop on. Athens, 3 November 2014 - 3 November 2014.

Preprints

  • Cullington H, Kitterick P, Darnton P, Finch T, Greenwell K, Riggs C, Weal M, Walker D-M & Sibley A (2021) , JMIR Publications Inc..
Grants
  • Electric Impedance Spectroscopy (EIS) and machine learning-based decision support system for early diagnosis of oral cancer, Yorkshire Cancer Research, 03/2024 - 02/2027, 瞿496,656, as PI
  • SANO: , EC H2020, 08/2019 - 07/2026, 瞿2,497,386, as Co-PI
  • SBRI Phase 2: Prototype development, Industrial, 01/2020 - 05/2021, 瞿178,944, as Co-PI
  • Using mechanistic computational simulation and machine learning to inform instrument design for EIS-guided surgery, Industrial, 10/2019 - 09/2023, 瞿106,804, as PI
  • PRIMAGE: , EC H2020, 12/2018 to 05/2023, 瞿549,018, as PI
  • CHIC: Computational Horizons in Cancer, EC FP7, 04/2013 to 03/2017, 瞿777,005, as Co-PI
  • A combined in vitro and in virtuo multi-scale approach to understanding individual and integrated cell behaviour during homeostasis and wound repair, The Wellcome Trust, 09/2010 to 09/2013, 瞿140,547, as PI
  • MeDDiCA: Medical Devices Design in Cardiovascular Applications, University College London, 09/2009 to 08/2013, 瞿340,386, as Co-PI
  • The Virtual Tendon - a multi-scale computational model of dnamical tissue remodelling, Arthritis Research Campaign, 09/2009 to 08/2012, 瞿155,321, as PI
  • Engineering Virus-like Nanoparticles for Targeting the Central Nervous System, EPSRC, 05/2009 to 08/2012, 瞿2,109,411, as Co-PI
Professional activities and memberships
  • Member of the  research group
  • Deputy Director of Undergraduate Admissions

Links

Complex Systems Modelling research group