Professor Ipsita Roy
PhD, MSc, BSc
School of Chemical, Materials and Biological Engineering
Professor of Biomaterials
Deputy School Director of Research and Innovation
CDT Co-Director Advanced Biomedical Materials
  
  +44 114 222 5962
Full contact details
School of Chemical, Materials and Biological Engineering
Sir Robert Hadfield Building
Mappin Street
Sheffield
S1 3JD
- Profile
 - 
    
Previously to joining the Department of Material Science and Engineering as Professor of Biomaterials, I was Professor at the School of Life Sciences, University of Westminster, London. I am also Visiting Professor at the National Heart and Lung Institute, Faculty of Medicine, Imperial College London.
I was awarded the prestigious Inlaks Scholarship and the Overseas Research Students Award to study for my PhD at the University of Cambridge. During my time at Cambridge, I was awarded the Churchill College Scholarship, the Lundgren Scholarship, Leche Trust Scholarship and the Cambridge University Philosophical Society Fellowship Award.
My PhD at the Department of Biochemistry was on a B12-dependent enzyme, methylmalonyl-CoA mutase. My postdoctoral work was at the University of Minnesota, USA, at the Bioprocess Technology Institute, where I worked on fatty acid biosynthesis.
Subsequently, I taught at the Indian Institute of Technology, India, for four years as an Assistant Professor. During this time I worked actively on the production of biodegradable polymers from Streptomyces.
I was at the University of Westminster from 2000 until August 2019, where I was the Research Director of the School of Life Sciences and led the Applied Biotechnology Research Group.
I have published over 100 papers in high ‘Impact Factor’ journals such as Biomaterials, Biomacromolecules, Journal of Royal Society Interface, Acta Biomaterialia and ACS Applied Materials Interfaces, and have presented my work at numerous international conferences.
 
- Research interests
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Natural Polymers of bacterial origin and their use in medical and environmentally friendly applications.
Her group is currently focussed on the production of novel Polyhydroxyalkanoates (PHAs), a group of FDA-approved natural polymers and their characterisation. She has pioneered the production of PHAs from Gram positive bacteria which lack immunogenic properties and hence are excellent materials for medical applications. Her group is involved in the application of PHAs in the area of hard tissue engineering, soft tissue engineering, wound healing, drug delivery and medical device development. She has also initiated work with bacterial cellulose and γ-polyglutamic acid, as natural polymers for biomedical applications. PHAs are also environmentally friendly polymers that are biodegradable both in the soil and in the sea. She has recently initiated work related to this aspect of PHAs.
Her work has been funded by the EPSRC, BHF, EU, DuPont, 3D BIONET (MRC), CYCLOPS (EPSRC) and WESTFOCUS, London. Professor Roy has been the scientific coordinator of two large EU projects REBIOSTENT, worth 4.9 million Euros with 14 consortium members and HYMEDPOLY, worth 3.5 million Euros with 12 consortium members. She was also the work package leader of another large EU FP7 project, NEURIMP, worth 4.4 million Euros with 8 consortium members.
Currently, she is work package leader in the H2020: BBI/JU project POLYBIOSKIN worth 3 million Euros with 12 consortium members. All four projects involve the use of PHAs for medical applications, drug eluting biodegradable stents, nerve guidance conduits, antibacterial polymers and wound healing. She is co-PI in the BHF funded Cardiovascular Regenerative Medicine Centre led by Imperial College London. She has received EPSRC funding for the development of smart wound healing patches (CYCLOPS) and drug eluting biodegradable stents.
She was awarded the ICURe, Innovation to Commercialisation, grant worth £34,905 from Innovate UK for exploring the commercial potential of Biobased Plastics for Medical Applications. She has an ongoing UKERI project on the development of a 3D disease model for cancer. She has been awarded a H2020: BBI/JU grant, ECOAT, where for the first time she will be exploring the green and environmentally friendly aspect of the PHAs and bacterial cellulose for the development of eco-sustainable multifunctional bio-based coatings with enhanced performance and end of life options. This project is worth 4.6 million and includes 16 partners.
Finally, her most recent grant is from the 3D BIONET and involves the development of 3D cardiac tissue model and includes mathematical modelling in collaboration with the University of Oxford and Imperial College London.
 
- Publications
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Books
- . Elsevier.
 
Journal articles
- . Frontiers in Bioengineering and Biotechnology, 13.
 - . Materials Today Bio, 34.
 - . Materials Today Bio, 33, 101932-101932.
 - . Macromolecular Materials and Engineering.
 - . Scientific Reports, 15.
 - . Molecular Neurobiology, 62(10), 12445-12460.
 - . Analytical Methods, 17(18), 3694-3704.
 - . Polymers, 17(9).
 - . Journal of Biochemical and Molecular Toxicology, 39(3).
 - . Acta Pharmacologica Sinica, 46(6), 1511-1538.
 - . Analytical Biochemistry, 700, 115788-115788.
 - . Biochemistry, 64(6), 1233-1243.
 - . New Biotechnology, 83, 133-141.
 - . ACS Biomaterials Science & Engineering, 10(8), 5136-5153.
 - . International Journal of Biological Macromolecules, 268, 131476-131476.
 - . Drug Discovery Today, 29(5), 103974-103974.
 - . Tissue Engineering Part A, 30(7-8), 340-356.
 - . Autophagy Reports, 2(1).
 - . Regenerative Biomaterials, 10.
 - . Macromolecular Bioscience, 23(11).
 - . Biomaterials Science, 11(17), 5706-5726.
 - . Current Opinion in Biomedical Engineering, 28.
 - . Life Sciences, 328, 121871-121871.
 - . ACS Chemical Neuroscience, 14(12), 2385-2395.
 - . ACS Biomaterials Science & Engineering, 9(3), 1472-1485.
 - . The FEBS Journal, 290(12), 3270-3289.
 - . Bioscience Reports, 43(2), BSR20220324.
 - . Journal of Functional Biomaterials, 14(1).
 - . International Journal of Molecular Sciences, 24(2).
 - . Protein & Peptide Letters, 30(5), 361-366.
 - . Materials Letters, 323, 132530-132530.
 - . ACS Chemical Neuroscience, 13(18), 2728-2742.
 - . Applied Microbiology and Biotechnology, 106(18), 6169-6180.
 - . Cancers, 14(14).
 - . Journal of Industry, Competition and Trade, 22(2), 233-257.
 - . Trends in Molecular Medicine, 28(4), 331-342.
 - . Tissue Engineering Part B: Reviews, 28(3), 633-664.
 - . Frontiers in Bioengineering and Biotechnology, 9.
 - . International Journal of Molecular Sciences, 22(23).
 - . Frontiers in Neuroscience, 15.
 - . Materials, 14(17).
 - . ACS Applied Materials & Interfaces, 13(28), 32624-32639.
 - . Materials Science and Engineering: R: Reports, 145.
 - . Bioengineering & Translational Medicine, 6(3).
 - . Frontiers in Bioengineering and Biotechnology, 9.
 - . Applied Sciences, 11(9).
 - . Frontiers in Bioengineering and Biotechnology, 9.
 - . Polymers, 13(7).
 - . Frontiers in Bioengineering and Biotechnology, 9(1).
 - . ACS Biomaterials Science & Engineering, 7(2), 672-689.
 - . Ceramics International, 47(3), 3876-3883.
 - . Nanomaterials, 11(1).
 - . International Journal of Molecular Sciences, 21(24).
 - . Frontiers in Cardiovascular Medicine, 7.
 - . Frontiers in Bioengineering and Biotechnology, 8(-), ---.
 - . Journal of Functional Biomaterials, 11(3).
 - . Frontiers in Bioengineering and Biotechnology, 8.
 - . Frontiers in Bioengineering and Biotechnology, 8.
 - . Biomedical Materials, 15(4).
 - . Materials, 13(11).
 - . Frontiers in Bioengineering and Biotechnology, 8, ---.
 - . Journal of Functional Biomaterials, 11(2).
 - . Polymers, 12(1).
 - . ACS Omega, 4(22), 19746-19755.
 - . Biochemical Engineering Journal, 150, 107283-107283.
 - . Journal of Tissue Engineering and Regenerative Medicine, 13(9), 1581-1594.
 - . Chemistry of Materials, 31(15), 5450-5463.
 - . Expert Review of Medical Devices, 16(6), 467-482.
 - . Osteoarthritis and Cartilage, 27, S432-S433.
 - . Journal of Materials Science: Materials in Medicine, 29(12).
 - . ACS Applied Materials & Interfaces, 10(30), 25056-25068.
 - . Acta Biomaterialia, 71, 225-234.
 - . Journal of Materials Science: Materials in Medicine, 29(3).
 - . Journal of Tissue Engineering and Regenerative Medicine, 12(1), e495-e512.
 - . Microbial Biotechnology, 10(6), 1384-1399.
 - . Carbohydrate Polymers, 171, 220-228.
 - . Journal of Chemical Technology & Biotechnology, 92(7), 1548-1557.
 - . International Journal of Polymeric Materials and Polymeric Biomaterials, 66(7), 326-335.
 - . Journal of Nanomaterials, 2016, 1-14.
 - . Macromolecular Materials and Engineering, 301(8), 881-881.
 - . Macromolecular Materials and Engineering, 301(8), 922-934.
 - . Polymer International, 65(6), 661-674.
 - . Polymer International, 65(7), 780-791.
 - . Journal of Biomaterials Applications, 31(1), 77-91.
 - . Polymer International, 65(7), 741-746.
 - . Engineering in Life Sciences, 15(6), 612-621.
 - . Journal of Chemical Technology & Biotechnology, 90(7), 1167-1168.
 - . Journal of Chemical Technology & Biotechnology, 90(7), 1209-1221.
 - . Carbohydrate Polymers, 126, 47-51.
 - . Enzyme and Microbial Technology, 61-62, 61-66.
 - . Journal of Biomaterials and Nanobiotechnology, 05(04), 229-240.
 - . Microbial Physiology, 23(6), 391-395.
 - . Journal of Materials Science: Materials in Medicine, 24(12), 2809-2817.
 - . Expert Opinion on Drug Delivery, 10(10), 1353-1365.
 - . Reactive and Functional Polymers, 73(10), 1340-1348.
 - . Bioinspired, Biomimetic and Nanobiomaterials, 2(3), 141-153.
 - , 397-421.
 - . Advanced Engineering Materials, 14(6).
 - . Biotechnology Journal, 7(2), 293-303.
 - . International Journal of Molecular Sciences, 12(7), 4294-4314.
 - . Biomacromolecules, 12(6), 2126-2136.
 - . Journal of Applied Electrochemistry, 41(8), 919-923.
 - . Materials Science and Engineering: R: Reports, 72(3), 29-47.
 - . Scanning, 33(2), 59-68.
 - . Biotechnology Letters, 33(5), 985-991.
 - , 79-101.
 - . Advanced Engineering Materials, 12(7).
 - . Applied Microbiology and Biotechnology, 88(1), 65-73.
 - . Journal of Chemical Technology & Biotechnology, 85(6), 731-731.
 - . Journal of Chemical Technology & Biotechnology, 85(6), 732-743.
 - . Current Opinion in Microbiology, 13(3), 321-326.
 - . Biomaterials, 31(10), 2806-2815.
 - . Acta Biomaterialia, 6(7), 2773-2786.
 - . Journal of Chemical Technology & Biotechnology, 85(6), 760-767.
 - . Acta Biomaterialia, 6(3), 735-742.
 - . Journal of The Royal Society Interface, 7(44), 453-465.
 - . Materials Chemistry and Physics, 118(2-3), 420-426.
 - . Journal of Applied Microbiology, 107(4), 1131-1139.
 - . Biomacromolecules, 10(4), 691-699.
 - . Journal of Tissue Engineering and Regenerative Medicine, 3(2), 139-148.
 - . Journal of The Royal Society Interface, 6(33), 401-409.
 - . Biotechnology Letters, 30(9), 1665-1670.
 - . Biomaterials, 29(12), 1750-1761.
 - . Journal of Molecular Catalysis B: Enzymatic, 50(2-4), 114-120.
 - . Journal of Applied Microbiology, 104(6), 1624-1635.
 - . Metabolomics, 4(1), 52-62.
 - Biodegradable polymer coated 45S5 Bioglass-derived glass-ceramic scaffolds for bone tissue engineering. Glass Technology European Journal of Glass Science and Technology Part A, 48(5), 227-234.
 - . Journal of Biotechnology, 131(4), 397-403.
 - Fighting protein misfolding diseases. Pharmaceutical Technology Europe, 19(6), 34-44.
 - . Biomacromolecules, 8(7), 2112-2119.
 - . Enzyme and Microbial Technology, 40(6), 1518-1523.
 - . Journal of Biotechnology, 132(3), 251-258.
 - . Journal of Chemical Technology & Biotechnology, 82(3), 233-247.
 - . Nanotechnology, 18(7), 075701-075701.
 - . Journal of Biotechnology, 127(3), 475-487.
 - . Expert Review of Medical Devices, 3(6), 853-868.
 - . Antonie van Leeuwenhoek, 91(1), 1-17.
 - . Biomacromolecules, 7(8), 2249-2258.
 - . Biomaterials, 27(7), 964-973.
 - . Biochemical Engineering Journal, 23(3), 193-198.
 - . Journal of Chromatography A, 1069(2), 155-161.
 - . Enzyme and Microbial Technology, 34(1), 26-32.
 - , 159-189.
 - . Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1647(1-2), 361-366.
 - . Archives of Microbiology, 179(1), 66-69.
 - . Journal of Bacteriology, 180(18), 4828-4833.
 - A methylmalonyl-CoA mutase in Escherichia coli?. Protein Engineering, 10(3333), 68.
 - . FEBS Letters, 394(2), 126-128.
 - . Journal of Bacteriology, 174(17), 5763-5764.
 - . NeuroMolecular Medicine, 26(1).
 - . International Materials Reviews, 1-39.
 - . RSC Sustainability, 1(7), 1722-1736.
 - . Frontiers in Molecular Biosciences, 9.
 - . Journal of Functional Biomaterials, 11(3), 62-62.
 - . Chemical and Biochemical Engineering Quarterly, 29(2), 157-172.
 
Book chapters
- , Cellular Osmolytes (pp. 1-16). Springer Nature Singapore
 - , Pluripotent Stem Cell Therapy for Diabetes (pp. 221-250). Springer International Publishing
 - , Some Key Topics in Chemistry and Biochemistry for Biotechnologists (pp. 44-63). CRC Press
 - , Recent Advances in Pharmaceutical Innovation and Research (pp. 3-40). Springer Nature Singapore
 - , Three Phase Partitioning (pp. 197-222). Elsevier
 - , Three Phase Partitioning (pp. 175-196). Elsevier
 - , The Handbook of Polyhydroxyalkanoates (pp. 255-284). CRC Press
 - (pp. 89-138). Academic Press (Elsevier)
 - , Polymers and Polymeric Composites: A Reference Series (pp. 1131-1148). Springer International Publishing
 - , Gene Therapy in Neurological Disorders (pp. 207-228). Elsevier
 - , Polymers and Polymeric Composites: A Reference Series (pp. 1-18). Springer International Publishing
 - , Economic Complexity and Evolution (pp. 357-391). Springer International Publishing
 - , Science and Principles of Biodegradable and Bioresorbable Medical Polymers (pp. 257-277). Elsevier
 - (pp. 337-383). Wiley
 - Polyhydroxyalkanoates: A new generation of biotechnologically produced biodegradable polymers, Biodegradable Materials Production Properties and Applications (pp. 173-215).
 - Polyhydroxyalkanoates: A new generation of biotechnologically produced biodegradable polymers, Biotechnology Research Technology and Applications (pp. 1-46).
 - , Methods for Affinity-Based Separations of Enzymes and Proteins (pp. 1-15). Birkhäuser Basel
 - , Methods for Affinity-Based Separations of Enzymes and Proteins (pp. 130-147). Birkhäuser Basel
 
Conference proceedings
- Tissue repair with multimaterial biomedical devices fabricated from sustainable biopolymers. TISSUE ENGINEERING PART A, Vol. 29(13-14)
 - Polyhydroxyalkanoates: A family of natural polymers, for medical implant development and disease modelling. Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, Vol. 40 (pp 760)
 - Polyhydroxyalkanoates, ideal materials for cardiac regeneration. Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, Vol. 40 (pp 442)
 - PERIPHERAL NERVE REGENERATION USING BLENDS OF POLYHYDROXYALKANOATES. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, Vol. 20(2) (pp 185-185)
 - Nerve Tissue Engineering using Blends of Polyhydroxyalkanoates for Peripheral Nerve Regeneration. TISSUE ENGINEERING PART A, Vol. 21 (pp S325-S325)
 - (pp 159-175)
 - . Chemical Engineering Transactions, Vol. 32 (pp 931-936)
 - Production of medium chain length polyhydroxyalkanoates in recombinant Bacillus subtilis. 24th European Conference on Biomaterials Annual Conference of the European Society for Biomaterials
 - Production of polyhydroxyalkanoates by pseudomonas mendocina using vegetable oils as the sole carbon source. 24th European Conference on Biomaterials Annual Conference of the European Society for Biomaterials
 - Polyhydroxyalkanoate (PHA)/Bacterial Cellulose composites for biomedical applications. 24th European Conference on Biomaterials Annual Conference of the European Society for Biomaterials
 - . Journal of Applied Polymer Science, Vol. 122(6) (pp 3606-3617)
 - . AIP Conference Proceedings (pp 126-128)
 - Optimisation of bioglass®-derived scaffolds for bone tissue engineering. 8th World Biomaterials Congress 2008, Vol. 3 (pp 1262)
 - Nano- versus micron-sized bioactive glass reinforcement of P(3HB) - Are nano-fillers the way forward?. 8th World Biomaterials Congress 2008, Vol. 2 (pp 863)
 
Preprints
- , arXiv.
 
 
- Research group
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Research Associates:
PhD students:
- Isabel Orlando (submitted) Novel hydrogel-based hybrid antibacterial polymers for wound healing applications (University of Westminster)
 - Sheila Piarali (submitted) Novel Antibacterial Agents for Innovative Antibacterial Polymers (University of Westminster)
 - Alexandra Paxinou (in progress) Novel Antibacterial Polymers of Natural Origin (University of Westminster)
 - Elena Marcello (in progress) PHA based Antibacterial Polymers for Tissue Engineering (University of Westminster)
 - Qasim Majid (in progress) PHA based regeneration of cardiac tissue (Second Supervisor, in collaboration with Professor Sian Harding, Imperial College London)
 - Maria Leite (in progress) The Biology of the surface of Mars (Second Supervisor, in collaboration with Professor Lewis Dartnell, University of Westminster)
 - Rebecca Barthenilla Garcia (in progress) Production of PHAs using sustainable biomass (Second Supervisor, in collaboration with Professor Lewis Dartnell, University of Westminster)
 - Anabelle Fricker (University of Sheffield)
 - Emmanuel Asare (University of Sheffield)
 
 
- Teaching interests
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- Organic Chemistry
 - Biochemistry
 - Molecular Biology
 - Biomaterials
 - Bioengineering
 - Tissue Engineering
 - Regenerative Medicine
 - Biotechnology
 - Drug Delivery
 
 
- Professional activities and memberships
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- Editor of the Journal of Chemical Technology and Biotechnology (JCTB)
 - Previously special editor of two In Focus Issues of JCTB on Biodegradable polymers and Controlled Drug Delivery
 - Grant reviewing panels for:
	
- Biotechnology and Biological Sciences Research Council (BBSRC)
 - Engineering and Physical Sciences Research Council (EPSRC)
 - Natural Sciences and Engineering Research Council of Canada
 - Austrian Science Fund (Fonds zur Förderung der wissenschaftlichen Forschung, FWF), Austria
 - National Natural Science Foundation of China
 - European Social Fund
 - MUIR
 
 - Best Chemistry Undergraduate Student Award, St. Stephen's College, 1984, 1985, 1986
 - Professor Seshadri Prize for being the best candidate in the BSc (Hons) Chemistry, University of Delhi, 1986
 - Best Biotechnology Masters Student Award, Jawaharlal Nehru University, New Delhi, 1988
 - Overseas Research Studentship from the Committee of Vice Chancellors and Principals, UK, 1989-1991
 - The Inlaks Scholarship, India, for doctoral studies at Cambridge, 1989-1990
 - Churchill College Scholarship, University of Cambridge, UK, 1991
 - Lundgren Scholarship, University of Cambridge, UK, 1992
 - Leche Trust Scholarship, London, UK, 1992
 - Cambridge University Philosophical Society Fellowship Award, Cambridge, UK, 1992
 - Nominated member of the New York Academy of Sciences in recognition of research activities, 1997
 
 
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