Professor Gwendolen Reilly (she/her)

DPhil, BSc

School of Chemical, Materials and Biological Engineering

School of Chemical, Materials and Biological Engineering

Professor of Musculoskeletal Bioengineering

School EDI lead

Co-chair of the staff Women's Network

Co-director of CDT in Advanced Biomedical Materials

Gwen Reilly
Profile picture of Gwen Reilly
g.reilly@sheffield.ac.uk
+44 114 222 5986
Pam Liversidge Building

Full contact details

Professor Gwendolen Reilly
School of Chemical, Materials and Biological Engineering
Pam Liversidge Building
Mappin Street
Sheffield
S1 3JD
Profile

Gwendolen Reilly has been a member of academic staff since 2004.

She received her DPhil in Biology at the University of York, specialising in bone biomechanics. She has previously undertaken post-doctoral research at the University of Pennsylvania, Pennsylvania State College of Medicine and the Swiss Federal Institute of Technology in cell biomechanics, biomaterials and bone structure respectively. Subsequently, she undertook a position as Research Assistant Professor in Bioengineering at the University of Illinois, Chicago specializing in tissue engineering.

Gwens current research combines her expertise in biomechanics, biomaterials and orthopaedics.

Research interests

The research has applications in orthopaedic and dental medicine, where clinicians are looking for improved methods to repair skeletal tissues; bone, tendon and cartilage.

Bone tissue engineering
The aim of bone tissue engineering is to create bone matrix in the laboratory for clinical implantation and as an experimental tool. Our research in this area focuses on two main themes; the effects of mechanical stimulation on differentiation and matrix formation by bone cells and the interactions between precursor bone cells and their biomaterial substrate. Mechanical stimuli examined include dynamic compression, stretch and fluid flow induced shear stresses using a range of bioreactors (including a collaboration with ElectroForce systems group).

Musculoskeletal cell mechanobiology
We are interested in how skeletal cells respond to extrinsic and intrinsic stimuli by organizing the proteins and mineral they secrete in a way which enhances the strength of the matrix. This information can then be used to manipulate tissue-engineered structures in order to induce structurally sound matrix formation. We specifically focus on mechanosensation mechanisms found on the cell membrane; the cells proteoglycan (sugar-based) coat and a small organelle that protrudes from the cell membrane the primary cilia.

Orthopaedic biomaterials
We investigate the interactions between musculoskeletal cells and orthopaedic and dental materials that are implanted into bone. Materials investigated include porous metals, polymer scaffolds and peptide coated surfaces (in collaboration with Orla Protein Technologies). This research encompasses the study of the mechanical properties of biomaterial scaffolds, cell-material interactions, cell mechanics and cell signalling.

Publications

Journal articles

  • Munive Olarte A, Durgut E, Verbruggen S, Claeyssens F & Reilly G (2025) . Biomedical Materials, 20(6).
  • Sengokmen-Ozsoz N, Aleemardani M, Palanca M, Hann A, Reilly G, Dall'Ara E & Claeyssens F (2024) . Biofabrication, 17(1).
  • Paterson TE, Owen R, Sherborne C, Bahmaee H, Harding AL, Green NH, Reilly GC & Claeyssens F (2024) . Journal of Materials Chemistry B: Materials for biology and medicine, 12(45), 11746-11758.
  • Morita M, Arshad F, Quayle LA, George CN, Lefley DV, Kalajzic I, Balsubramanian M, Cebe T, Reilly G, Bishop NJ & Ottewell PD (2024) . Bone Reports, 22.
  • Owen R, Wittkowske C, Lacroix D, Perrault CM & Reilly GC (2024) . Connective Tissue Research, 65(4), 313-329.
  • Akhtar H, Alhamoudi FH, Marshall J, Ashton T, Darr JA, Rehman IU, Chaudhry AA & Reilly G (2024) . Heliyon, 10(7), e29150-e29150.
  • Gupta D, Martinez DC, Puertas-Mej穩a MA, Hearnden VL & Reilly GC (2024) . International Journal of Molecular Sciences, 25(4).
  • Verbruggen SW, Sittichokechaiwut A & Reilly GC (2023) . Current Osteoporosis Reports, 21(6), 719-730.
  • Furmidge R, Jackson CE, Vel獺zquez de la Paz MF, Workman VL, Green NH, Reilly GC, Hearnden V & Claeyssens F (2023) . Frontiers in Chemistry, 11.
  • AL-Hamoudi F, Rehman HU, Almoshawah YA, Talari ACS, Chaudhry AA, Reilly GC & Rehman IU (2022) . International Journal of Molecular Sciences, 23(18).
  • Durgut E, Sherborne C, Aldemir Dikici B, Reilly GC & Claeyssens F (2022) . Langmuir, 38(36), 10953-10962.
  • Maksoud FJ, de la Paz FV, Hann A, Thanarak J, Reilly G, Claeyssens F, Green N & Zhang YS (2022) . Journal of Materials Chemistry B, 40, 8111-8165.
  • Unune DR, Brown GR & Reilly GC (2022) . Vacuum, 203.
  • Krstic N, Bishop N, Curtis B, Cooper C, Harvey N, Lilycrop K, Murray R, Owen R, Reilly G, Skerry T & Borg S (2022) . Genes & Nutrition, 17(1).
  • Delaine-Smith RM, Hann AJ, Green NH & Reilly GC (2021) . Frontiers in Bioengineering and Biotechnology, 9.
  • Khan HQRB & Reilly GC (2021) . Applied Sciences, 11(15).
  • Oliviero S, Roberts M, Owen R, Reilly GC, Bellantuono I & DallAra E (2021) . Biomechanics and Modeling in Mechanobiology, 20(3), 941-955.
  • Oliviero S, Owen R, Reilly GC, Bellantuono I & Dall'Ara E (2021) . Journal of the Mechanical Behavior of Biomedical Materials, 113.
  • Bahmaee H, Owen R, Boyle L, Perrault CM, Garcia-Granada AA, Reilly GC & Claeyssens F (2020) . Frontiers in Bioengineering and Biotechnology, 8.
  • Owen R, Sherborne C, Evans R, C. Reilly G & Claeyssens F (2020) . International Journal of Bioprinting, 6(2), 99-113.
  • Aldemir Dikici B, Reilly GC & Claeyssens F (2020) . ACS Applied Materials & Interfaces, 12(11), 12510-12524.
  • Gupta D, Kocot M, Tryba AM, Serafim A, Stancu IC, Jaegermann Z, Pamua E, Reilly GC & Douglas TEL (2020) . Materials & Design, 188.
  • Amnael Orozco-D穩az C, Moorehead R, Reilly GC, Gilchrist F & Miller C (2020) . Biomedical Physics & Engineering Express, 6(2).
  • Gupta D, Silva M, Radziun K, Martinez DC, Hill CJ, Marshall J, Hearnden V, Puertas-Mejia MA & Reilly GC (2020) . Marine Drugs, 18(2).
  • Owen R, Bahmaee H, Claeyssens F & Reilly G (2020) . Bioengineering, 7(1).
  • Dikici S, Aldemir Dikici B, Bhaloo SI, Balcells M, Edelman ER, MacNeil S, Reilly GC, Sherborne C & Claeyssens F (2020) . Frontiers in Bioengineering and Biotechnology, 7.
  • Green AC, Lath D, Hudson K, Walkley B, Down JM, Owen R, Evans HR, PatonHough J, Reilly GC, Lawson MA & Chantry AD (2019) . Journal of Bone and Mineral Research, 34(12), 2311-2326.
  • Aldemir Dikici B, Dikici S, Reilly GC, MacNeil S & Claeyssens F (2019) . Materials, 12(16).
  • Aldemir Dikici B, Sherborne C, Reilly GC & Claeyssens F (2019) . Polymer, 175, 243-254.
  • Sensini A, Gualandi C, Focarete ML, Belcari J, Zucchelli A, Boyle L, Reilly GC, Kao AP, Tozzi G & Cristofolini L (2019) . Biofabrication, 11(3), 035026-035026.
  • Marcotti S, Reilly GC & Lacroix D (2019) . Journal of the Mechanical Behavior of Biomedical Materials, 94, 259-266.
  • Shbeh M, Wally ZJ, Elbadawi M, Mosalagae M, Al-Alak H, Reilly GC & Goodall R (2019) . Journal of the Mechanical Behavior of Biomedical Materials, 96, 193-203.
  • Wally ZJ, Haque AM, Feteira A, Claeyssens F, Goodall R & Reilly GC (2019) . Journal of the Mechanical Behavior of Biomedical Materials, 90, 20-29.
  • Sensini A, Gualandi C, Zucchelli A, Boyle LA, Kao AP, Reilly GC, Tozzi G, Cristofolini L & Focarete ML (2018) . Scientific Reports, 8(1).
  • Marcotti S, Maki K, Reilly GC, Lacroix D & Adachi T (2018) . PLoS One, 13(10).
  • Sherborne C, Owen R, Reilly GC & Claeyssens F (2018) . Materials and Design, 156, 494-503.
  • Owen R & Reilly GC (2018) . Frontiers in Bioengineering and Biotechnology, 6.
  • Paterson TE, Gigliobianco G, Sherborne C, Green NH, Dugan JM, MacNeil S, Reilly GC & Claeyssens F (2018) . APL Bioengineering, 2(2).
  • Bhaskar B, Owen R, Bahmaee H, Wally Z, Sreenivasa Rao P & Reilly GC (2018) . Journal of Biomedical Materials Research Part A, 106(5), 1334-1340.
  • Puwanun S, Delaine-Smith RM, Colley HE, Yates JM, MacNeil S & Reilly GC (2018) . Journal of Tissue Engineering and Regenerative Medicine, 12(2), 370-381.
  • Borg SA, Buckley H, Owen R, Marin AC, Lu Y, Eyles D, Lacroix D, Reilly GC, Skerry TM & Bishop NJ (2018) . PLoS One, 13(1).
  • Bhaskar B, Owen R, Bahmaee H, Rao PS & Reilly GC (2018) . Applied Biochemistry and Biotechnology, 185(2), 555-563.
  • Antonini LM, Kothe V, Reilly GC, Owen R, Marcuzzo JS & Malfatti CDF (2017) . Journal of Materials Research, 32(20), 3811-3821.
  • Green NH, Delaine-Smith R, Askew HJ, Byers R, Reilly GC & Matcher SJ (2017) . Scientific Reports, 7.
  • Pogorielov M, Kravtsova A, Reilly GC, Deineka V, Tetteh G, Kalinkevich O, Pogorielova O, Moskalenko R & Tkach G (2017) . Journal of Materials Science: Materials in Medicine, 28(2).
  • Wittkowske C, Reilly GC, Lacroix D & Perrault CM (2016) . Frontiers in Bioengineering and Biotechnology, 4.
  • Heymann D, Baud'huin M, Lamoureux F, Jacques C, Rodriguez Calleja L, Quillard T, Amiaud J, Berreur M, Brounais-Le Royer B, Owen R , Reilly G et al (2016) . Bone.
  • Filipowska J, Reilly GC & Osyczka AM (2016) . Biotechnology and Bioengineering, 113(8), 1814-1824.
  • Puwanun S, Bye FJ, Ireland MM, MacNeil S, Reilly GC & Green NH (2016) . Polymers, 8(6), 221-229.
  • Wally Z, van Grunsven W, Claeyssens F, Goodall R & Reilly G (2016) . Metals, 6(5), 97-97.
  • Owen R, Sherborne C, Paterson T, Green NH, Reilly GC & Claeyssens F (2015) . Journal of the Mechanical Behavior of Biomedical Materials.
  • Owen R, Sherborne C, Reilly GC & Claeyssens F (2015) . Data Brief, 5, 616-620.
  • Wally ZJ, van Grunsven W, Claeyssens F, Goodall R & Reilly GC (2015) . Metals, 5(4), 1902-1920.
  • Viswanathan P, Ondeck MG, Chirasatitsin S, Ngamkham K, Reilly GC, Engler AJ & Battaglia G (2015) . Biomaterials, 52, 140-147.
  • Li X, Viceconti M, Cohen MC, Reilly GC, Carre MJ & Offiah AC (2015) . Journal of Biomechanics, 48(10), 2034-2040.
  • Viswanathan P, Themistou E, Ngamkham K, Reilly GC, Armes SP & Battaglia G (2015) . Biomacromolecules, 16(1), 66-75.
  • Tetteh G, Khan AS, Delaine-Smith RM, Reilly GC & Rehman IU (2014) . Journal of the Mechanical Behavior of Biomedical Materials, 39, 95-110.
  • van Grunsven W, Hernandez-Nava E, Reilly GC & Goodall R (2014) . Metals, 4(3), 401-409.
  • Delaine-Smith RM, Green NH, Matcher SJ, MacNeil S & Reilly GC (2014) . PLoS One, 9(2), e89761.
  • Yourek G, Xin X, Reilly GC & Mao JJ (2014) . Bio-Medical Materials and Engineering, 24(5), 1803-1815.
  • Rojo ES, Ramos M, Yates M, Martin-Luengo MA, Mart穩nez Serrano AM, Civantos A, L籀pez-Lacomba JL, Reilly G, Vervaet C, Tarterra JL , Luis BF et al (2014) . Rsc Advances, 4(25), 12630-12639.
  • Delaine-Smith RM, Sittichokechaiwut A & Reilly GC (2014) . FASEB J, 28(1), 430-439.
  • Bye FJ, Bissoli J, Black L, Bullock AJ, Puwanun S, Moharamzadeh K, Reilly GC, Ryan AJ & MacNeil S (2013) . Biomaterials Science, 1(9), 942-951.
  • Yeung WK, Reilly GC, Matthews A & Yerokhin A (2013) . Journal of Biomedical Materials Research Part B Applied Biomaterials, 101 B(6), 939-949.
  • Offiah AC, Reilly GC, Emerson NJ & Carr矇 MJ (2013) . Strain.
  • Delaine-Smith RM, MacNeil S & Reilly GC (2012) . Eur Cell Mater, 24, 162-174.
  • Shaeri M, Phillips S, Athey D, Chong CK & Reilly GC (2012) . Journal of Biomechanics, 45, S655-S655.
  • Mallick KK, Winnett J, van Grunsven W, Lapworth J & Reilly GC (2012) . J Biomed Mater Res A, 100(11), 2948-2959.
  • Delaine-Smith RM & Reilly GC (2012) Mesenchymal stem cell responses to mechanical stimuli. Muscles, Ligaments and Tendons Journal, 2, 169-180.
  • Rumney RMH, Sunters A, Reilly GC & Gartland A (2012) . J Biomech, 45(3), 549-554.
  • Emerson NJ, Carr矇 MJ, Reilly GC & Offiah AC (2011) . Procedia Engineering, 13, 422-427.
  • Oliver R, Glover M, Wang L, Reilly G & Rosario D (2011) . International Journal of Surgery, 9(7), 556-556.
  • Pamula E, Kokoszka J, Cholewa-Kowalska K, Laczka M, Kantor L, Niedzwiedzki L, Reilly GC, Filipowska J, Madej W, Kolodziejczyk M , Tylko G et al (2011) Degradation, Bioactivity, and Osteogenic Potential of Composites Made of PLGA and Two Different Sol-Gel Bioactive Glasses. Annals of Biomedical Engineering, 1-16.
  • Way LS, Gray C, Reilly G & Scutt A (2010) . Ifmbe Proceedings, 31 IFMBE, 926-929.
  • Puppi D, Detta N, Piras AM, Chiellini F, Clarke DA, Reilly GC & Chiellini E (2010) . Macromolecular Bioscience, 10(8), 887-897.
  • Yourek G, McCormick SM, Mao JJ & Reilly GC (2010) . Regenerative Medicine, 5(5), 713-724.
  • Morris HL, Reed CI, Haycock JW & Reilly GC (2010) . P I MECH ENG H, 224(H12), 1509-1521.
  • Flores-Merino MV, Chirasatitsin S, LoPresti C, Reilly GC, Battaglia G & Engler AJ (2010) . SOFT MATTER, 6(18), 4466-4470.
  • REILLY G & ENGLER A (2010) , 43(1), 55-62.
  • Detta N, Errico C, Dinucci D, Puppi D, Clarke DA, Reilly GC & Chiellini F (2010) . JOURNAL OF MATERIALS SCIENCE: MATERIALS IN MEDICINE, 21(5), 1761-1769.
  • Sittichokechaiwut A, Edwards JH, Scutt AM & Reilly GC (2010) SHORT BOUTS OF MECHANICAL LOADING ARE AS EFFECTIVE AS DEXAMETHASONE AT INDUCING MATRIX PRODUCTION BY HUMAN BONE MARROW MESENCHYMAL STEM CELLS. EUR CELLS MATER, 20, 45-57.
  • Flores-Merino MV, Chirasatitsin S, LoPresti C, Reilly GC, Battaglia G & Engler AJ (2010) Nanoscopic mechanical anisotropy in hydrogel surfaces (vol 6, pg 4466, 2010). SOFT MATTER, 6(24), 6211-6211.
  • Reilly G & Sittichockcahiwut A (2009) Development of a Culture System to Modulate Tissue Engineered Bone Formation by Varying Loading Conditions.. Proceedings of the 7th International Conference on Manufacturing ResearchProceedings of the 7th International Conference on Manufacturing Research, 443-448.
  • Sittichockechaiwut A, Scutt AM, Ryan AJ, Bonewald LF & Reilly GC (2009) . Bone, 44(5), 822-829.
  • Liang W, Rahaman MN, Day DE, Marion NW, Riley GC & Mao JJ (2008) . Journal of Non Crystalline Solids, 354(15-16), 1690-1696.
  • Rosario DJ, Reilly GC, Ali Salah E, Glover M, Bullock AJ & Macneil S (2008) . Regen Med, 3(2), 145-156.
  • Reilly GC, Radin S, Chen AT & Ducheyne P (2007) . Biomaterials, 28(28), 4091-4097.
  • STOSICH M, BASTIAN B, MARION N, CLARK P, REILLY G & MAO J (2007) . Tissue Engineering, 13(12), 2881-2890.
  • Sittichokechaiwut A, Ryan AJ & Reilly G (2006) . Journal of Biomechanics, 39, S219-S219.
  • YAO J, RADIN S, REILLY G, LEBOY P & DUCHEYNE P (2005) Solution-mediated effect of bioactive glass in poly (lactic-co-glycolic acid)-bioactive glass composites on osteogenesis of marrow stromal cells, 75A(4), 794-801.
  • Marion NW, Liang W, Reilly GC, Day DE, Rahaman MN & Mao JJ (2005) . MECHANICS OF ADVANCED MATERIALS AND STRUCTURES, 12(3), 239-246.
  • RADIN S, REILLY G, BHARGAVE G, LEBOY P & DUCHEYNE P (2005) . You have full text access to this content Journal of Biomedical Materials Research Part A, 73A(1), 21-29.
  • Reilly GC, Golden EB, Grasso-Knight G & Leboy PS (2005) . Cell Communication and signaling, 3(3).
  • Reilly GC, Haut TR, Yellowley CE, Donahue HJ & Jacobs CR (2003) Fluid flow induced PGE(2) release by bone cells is reduced by glycocalyx degradation whereas calcium signals are not. BIORHEOLOGY, 40(6), 591-603.
  • Diefenderfer D, Osyczka A, Reilly G & Leboy P (2003) . Connective Tissue Research, 44(1), 305-311.
  • Mante M, Daniels B, Golden E, Diefenderfer D, Reilly G & Leboy PS (2003) Attachment of human marrow stromal cells to titanium surfaces.. Journal of Oral Implantology, 29(2), 66-72.
  • DIEFENDERFER D, OSYCZKA A, REILLY G & LEBOY P (2003) BMP responsiveness in human mesenchymal stem cells, 44, 305-311.
  • Noble BS, Peet N, Stevens HY, Brabbs A, Mosley JR, Reilly GC, Reeve J, Skerry TM & Lanyon LE (2003) . Am J Physiol Cell Physiol, 284(4), C934-C943.
  • KNAPP H, REILLY G, STEMMER A, NIEDERER P & TATE M (2002) Development of preparation methods for and insights obtained from atomic force microscopy of fluid spaces in cortical bone. Scanning, 24(1), 25-33.
  • YOU J, REILLY G, ZHEN X, YELLOWLEY C, CHEN Q, DONAHUE H & JACOBS C (2001) . The Journal of Biological Chemistry, 276(16), 13365-13371.
  • BATSON E, REILLY G, CURREY J & BALDERSON D (2000) . Equine Veterinary Journal, 32(2), 95-100.
  • REILLY G & CURREY J (2000) . Journal of Biomechanics, 33(3), 337-343.
  • REILLY G (2000) . Journal of Biomechanics, 33(9), 1131-1134.
  • REILLY G & CURREY J (1999) The development of microcracking and failure in bone depends on the loading mode to which it is adapted. The Journal of Experimental Biology, 202(5), 543-552.
  • CURREY J, FOREMAN J, LAKETIC I, MITCHELL J, PEGG D & REILLY G (1997) . Journal of Orthopaedic Research, 15(1), 111-117.
  • REILLY G, CURREY J & GOODSHIP A (1997) . Journal of Orthopaedic Research, 15(6), 862-868.
  • CURREY J, BREAR K, ZIOUPOS P & REILLY G (1995) . Biomaterials, 16(16), 1267-1271.
  • Antonini LM, Santos Junior AGD, Reilly G & Malfatti CDF () . Materials Research, 21(5).
  • Rouholamin D, van Grunsven W, Reilly GC & Smith PJ () . Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 230(8), 761-774.
  • Reilly GC & Edwards JH () . World Journal of Stem Cells, 7(3), 568-582.

Book chapters

  • Marcotti S & Reilly GC (2017) (pp. 43-60). Wiley
  • Delaine-Smith RM & Reilly GC (2011) , VITAMINS AND HORMONES: STEM CELL REGULATORS (pp. 417-480).
  • Rahaman MN, Liang W, Day DE, Marion NW, Reilly GC & Mao JJ (2005) Preparation and bioacttve characteristics of porous borate glass substrates (pp. 3-10).
  • Yourek G, Al-Hadlaq A, Patel R, McCormick S, Reilly GC & Mao JJ (2004) , Bioelectric Engineering (pp. 69-97). Springer US
  • Martin-Luengo MA, Yates M, Ramos M, Salgado JL , Lacomba JL , Reilly G, Vervaet E, Saez-Rojo E, Fernandez-Munoz AI, Martinez-Serrano AM , Diaz M et al () , Sustainable Agriculture InTech

Conference proceedings

  • Ryan C, Reilly G & Claeyssens F (2025) Developing an angiogenic periosteum substitute to improve delayed bone healing. TISSUE ENGINEERING PART A, Vol. 31(11-12) (pp E894-E894)
  • Ryan CS, Reilly G & Claeyssens F (2024) Developing An Angiogenic Periosteum Substitute To Improve Delayed Bone Healing. TISSUE ENGINEERING PART A, Vol. 30(15-16) (pp S495-S495)
  • Akhtar H, Alhamoudi FH, Naz S, Khalid H, Khan AF & Reilly G (2024) Enhancing Alveolar Bone Regeneration:modulating Scaffold Properties Using Element Doped Zno Nanoparticles For Improved Cellular Dynamics And Mechanical Integrity. TISSUE ENGINEERING PART A, Vol. 30(15-16) (pp S437-S437)
  • Reilly G, Syla D, Rodrigues JO, Grillini L, Forte L, Bendoni R & Claeyssens F (2023) THE ROLE OF MULTIFUNCTIONAL NANOMATERIALS IN NEW TISSUE REGENERATION STRATEGIES. TISSUE ENGINEERING PART A, Vol. 29(11-12) (pp 828-828)
  • Hann A, Reilly GC, Green NH, Claeyssens F & Tetteh G (2023) MCSS SUPPORT A LAMELLA-LIKE TWISTING ORIENTATION OF COLLAGEN WHEN CULTURED ON ALIGNED ELECTROSPUN POLYCAPROLACTONE FIBRES. TISSUE ENGINEERING PART A, Vol. 29(11-12) (pp 1586-1587)
  • Cebe T, Balasubramanian M, Green N & Reilly G (2023) ELUCIDATION OF COLLAGEN FIBRE STRUCTURE IN OSTEOGENESIS IMPERFECTA USING SECOND HARMONIC GENERATION IMAGING ON POLYCAPROLACTONE FIBRES. TISSUE ENGINEERING PART A, Vol. 29(11-12) (pp 953-953)
  • Alhamoudii FHA, Alshadidi A, Kumar S, Chaudhry A, Reilly G & Rehman I (2023) Effect of HA Particle Size and Quantity on The Bioactive and Biological Behaviour of PU Scaffolds. TISSUE ENGINEERING PART A, Vol. 29(13-14)
  • Suvarna MV, Crawford A, Reilly GC, Claeyssens F & Green NH (2023) Development of an in vitro musculoskeletal model using poly (glycerol sebacate methacrylate) (PGSM) polyHIPE-based 3D microporous scaffold encompassing regionally controlled mechanical properties. TISSUE ENGINEERING PART A, Vol. 29(13-14)
  • Sasimonthon W, Reilly G, Colley H, Claeyssens F & Harding A (2023) CRANIOFACIAL BONE DEFECT REPAIR USING POLYMER SCAFFOLDS AND CELL DERIVED MATRIX. TISSUE ENGINEERING PART A, Vol. 29(11-12) (pp 1118-1119)
  • Akhtar H, Darr JA, Ashton T, Chaudhry AA, Rehman IU & Reilly G (2023) CERIUM, ZIRCONIUM AND COPPER DOPED ZINC OXIDE NANOPARTICLES FOR BONE REGENERATION AND ANGIOGENESIS. TISSUE ENGINEERING PART A, Vol. 29(11-12) (pp 1380-1381)
  • Ryan C, Reilly G & Claeyssens F (2023) Bone Clip: Developing an angiogenic biomaterial to increase bone healing. TISSUE ENGINEERING PART A, Vol. 29(13-14)
  • Suvarna MV, Crawford A, Reilly GC, Claeyssens F & Green NH (2023) Development of an in vitro musculoskeletal model using poly (glycerol sebacate methacrylate) (PGSM) polyHIPE-based 3D microporous scaffold encompassing regionally controlled mechanical properties. TISSUE ENGINEERING PART A, Vol. 29(13-14)
  • Alhamoudi FHA, Alshadidi A, Kumar S, Chaudhry A, Reilly G & Rehman I (2023) Effect of HA Particle Size and Quantity on The Bioactive and Biological Behaviour of PU Scaffolds. TISSUE ENGINEERING PART A, Vol. 29(13-14)
  • Ryan C, Reilly G & Claeyssens F (2023) Bone Clip: Developing an angiogenic biomaterial to increase bone healing. TISSUE ENGINEERING PART A, Vol. 29(13-14)
  • Cebe T, Balasubramanian M, Green N & Reilly G (2022) . Tissue Engineering Part A, Vol. 28(S1) (pp S601-S602). Maastricht, Netherlands, 15 November 2021 - 15 November 2021.
  • Sasimonthon W, Harding AL, Pashneh-Tala S, Claeyssens F, Colley H & Reilly GC (2022) CRANIOFACIAL BONE DEFECT REPAIR USING POLYMER SCAFFOLDS AND CELL DERIVED MATRIX. TISSUE ENGINEERING PART A, Vol. 28 (pp S551-S552)
  • Alhamoudi F, Alshadidi A, Kumar SV, Aldosari L, Chaudhry AA, Reilly GC & Rehman IU (2022) Effect of HA particle size and quantity on the bioactive and biological behaviour of PU scaffolds. TISSUE ENGINEERING PART A, Vol. 28 (pp 480-480)
  • Dikici S, Dikici BA, Reilly G & Claeyssens F (2018) Investigating the barrier membrane properties of biphasic PCL scaffolds for guided tissue regeneration. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 256
  • Dikici BA, Reilly G & Claeyssens F (2018) Assessment of the osteogenic and angiogenetic potential of in vitro generated extracellular matrix decorated multiscale porous polyHIPE scaffolds. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 256
  • Tetteh G, Delaine-Smith R, Green N & Reilly G (2016) Collagen and Mineral Deposition by MLO-A5 Late-Stage Osteoblasts, is Guided by the Fibre Alignment of Electrospun Scaffolds. Proceedings of the 22nd Congress of the European Society of Biomechanics, 10 July 2016 - 13 July 2016.
  • Paterson TE, Dugan JM, Sherborne C, Green NH, Reilly GC & Claeyssens F (2015) Highly Porous Particles for Cell Recruitment and Delivery in Bone Tissue Engineering. TISSUE ENGINEERING PART A, Vol. 21 (pp S287-S288)
  • Paterson T, Sherborne C, Chen CC, Reilly G & Claeyssens F (2014) . The University of Sheffield Engineering Symposium Conference Proceedings Vol. 1, Vol. 1. The Octagon Centre, University of Sheffield
  • Tetteh G, Rehman IU & Reilly GC (2014) Using composite scaffolds to engineer bone templates for in-vitro testing. Bone Research Society Conference. Sheffield, 11 May 2014.
  • Tetteh G, Rehman IU & Reilly GC (2013) A polyurethane-hydroxyapatite composite scaffold as a template for an in-vitro bone model. ICMOBT 2013. Spain, 8 December 2013 - 12 December 2013.
  • Tetteh G, Rehman IU & Reilly GC (2013) Using Electrospun Composite Scaffolds as a Template for In-Vitro Bone Matrix Formation. Proc. of the 7th MSC Meeting. Birmingham, 12 September 2013 - 13 September 2013.
  • Emerson NJ, Carre MJ, Reilly GC & Offiah AC (2013) . 6TH ASIA-PACIFIC CONGRESS ON SPORTS TECHNOLOGY (APCST), Vol. 60 (pp 459-466)
  • Tetteh G, Rehman IU & Reilly GC (2013) Polyurethane-Hydroxyapatite composite scaffolds for in vitro bone tissue engineering. European Cells and Materials, Vol. 26(7) (pp 38)
  • Delaine-Smith RM & Reilly GC (2012) Primary cilia removal inhibits osteoblastic matrix-forming response to mechanical stimuli. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 6
  • van Grunsven W, Goodall R & Reilly GC (2012) . Journal of Biomechanics, Vol. 45 (pp S339-S339)
  • Chirasatitsin S, Vishwanathan P, Reilly G, Battaglia G & Engler AJ (2012) Diblock copolymer foam surface chemistry influences mesenchymal stem cell fate. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 243
  • Shaeri M, Chong CK, Reilly G & Delain-Smith R (2012) Mechanical stimulation of mesenchymal stem cells in a 3D glass scaffold using oscillating and unidirectional flow. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 6 (pp 344-344)
  • Puwanun S, Bye F, Delaine-Smith RM, Yates J, MacNeil S & Reilly GC (2012) Optimizing cell sources for cleft palate repair. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 6 (pp 4-4)
  • Malayeri A, Gabbott C, Reilly G, Ghassemieh E, Hatton PV & Claeyssens F (2012) Feasibility of 3D printing and stereolithography for fabrication of custom-shaped poly (lactic acid): hydroxyapatite composite biomaterial scaffolds. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 6 (pp 367-367)
  • Wang N, Robaye B, Agrawal A, Reilly G, Boeynaems JM & Gartland A (2011) . BONE, Vol. 48 (pp S227-S227)
  • Flores-Merino MV, Reilly GC & Battaglia G (2011) Synthesis of interpenetrating polymer networks scaffolds of poly (vinyl pyrrolidone) and poly (acrylic acid). European Cells and Materials, Vol. 22(SUPPL.2) (pp 45)
  • van Grunsven W, Goodall R & Reilly GC (2011) Porous metal implants for enhanced bone ingrowth and stability. European Cells and Materials, Vol. 22(SUPPL.3) (pp 1)
  • Morris HL, Haycock JW & Reilly GC (2011) Hyaluronan as a potential mechanotransduction mediator. European Cells and Materials, Vol. 22(SUPPL.2) (pp 6)
  • Bye F, Puwanun S, Reilly G & MacNeil S (2011) Using a tissue engineering approach for the treatment of cleft palate. European Cells and Materials, Vol. 22(SUPPL.3) (pp 6)
  • Delaine-Smith RM, Reilly G & MacNeil S (2011) Response of dermal fibroblasts to dynamic tensile loading. European Cells and Materials, Vol. 22(SUPPL.2) (pp 41)
  • Viswanathan P, Chirasatitsin S, Reilly G, Engler A & Battaglia G (2011) 3D cell instructive scaffolds to direct stem cell fate. Technical Proceedings of the 2011 Nsti Nanotechnology Conference and Expo Nsti Nanotech 2011, Vol. 3 (pp 256-259)
  • Flores-Merino MV, Reilly GC, Engler AJ & Battaglia G (2009) Nano-domain detection in Poly (vinyl pyrrolidinone) hydrogels. European Cells and Materials, Vol. 18(SUPPL. 2) (pp 33)
  • Sittichokechaiwut A, Jacobs CR & Reilly GC (2009) Mechanical responses of bone tissue formation in 3D engineered constructs via primary cilia. European Cells and Materials, Vol. 18(SUPPL. 2) (pp 16)
  • Sittichokechaiwut A & Reilly G (2009) Development of a Culture System to Modulate Tissue Engineered Bone Formation by Varying Loading Conditions.. Proceedings of the 7th International Conference on Manufacturing Research, Vol. 7 (pp 443-448)
  • Flores-Merino MV, Ryan AJ, Reilly G & Battaglia. G (2008) Nanofunctionalization of hydrogels using amphiphilic copolymers.. 8th World Biomaterials Congress 2008, Vol. 2 (pp 1062)
  • Stevens-Smith JL, Scutt A & Reilly G (2008) Interactions between Obesity, Cardiovascular Disease and Bone Formation.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 23 (pp S489-S489)
  • Morris HL, Sittichokechaiwut A, Jacobs CR, Haycock JW & Reilly GC (2008) The Response of Matrix Synthesizing MLO-A5 Cells to Fluid Shear. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 23 (pp S147-S147)
  • Clarke D, Coll C, Ryan A, Crawford A & Reilly G (2008) . Journal of Biomechanics, Vol. 41 (pp S385-S385)
  • Sittichokechaiwut A, Scutt AM & Reilly GC (2008) . Journal of Biomechanics, Vol. 41 (pp S193-S193)
  • Flores-Merino MV, Reilly G & Battaglia G (2008) Nanofuntionalized polymeric networks for tissue engineering applications. European Cells and Materials, Vol. 16(SUPPL. 3) (pp 54)
  • Morris HL, Haycock JW & Reilly GC (2008) The role of mechanotransduction in bone tissue engineering. European Cells and Materials, Vol. 16(SUPPL. 3) (pp 84)
  • Rumney RMH, Sittichokechaiwut A, Reilly G & Gartland A (2008) ATP release from osteoblasts is increased in response to mechanical loading by different amounts when grown in standard monolayer and novel 3D scaffolds. CALCIFIED TISSUE INT, Vol. 83(1) (pp 16-16)
  • Sebastine IM, Sittichokechaiwut A, Clarke DA, Williams C, Reilly GC & Williams DJ (2008) Effects of frequency and loading duration on mechanically modulated collagen production by osteoblasts in bone tissue engineering. TISSUE ENGINEERING PART A, Vol. 14(5) (pp 844-844)
  • Rumney R, Wang N, Sittichokechaiwut A, Reilly G & Gartland A (2008) Different types of mechanical loading induce differentitial ATP release from osteoblasts grown on 3-dimensional scaffolds. PURINERG SIGNAL, Vol. 4 (pp S164-S165)
  • Clarke D, Puppi D, Detta N, Ferrer MCC, Crawford A, Reilly G & Chiellini F (2008) Electrospun polyurethane scaffolds for mechanical stimulation of cells in bone tissue engineering. TISSUE ENGINEERING PART A, Vol. 14(5) (pp 846-846)
  • Sittichokechaiwut A, Tummala P, Reilly G & Jacobs C (2008) The role of the primary cilia in mediating mechanically induced increases in matrix production during bone tissue engineering. TISSUE ENGINEERING PART A, Vol. 14(5) (pp 788-788)
  • Rumney RMH, Sittichokechaiwut A, Reilly GC & Gartland A (2008) Cyclical compressive loading induces changes in cellular behaviour and ATP release from osteoblasts grown on 3-dimensional scaffolds. CALCIFIED TISSUE INT, Vol. 82 (pp S115-S116)
  • Sittichokechaiwut A, Scutt A & Reilly GC (2007) The effects of compressive loading on matrix production by osteoblastic cells cultured in polyurethane scaffolds. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 22 (pp S359-S359)
  • Sittichockechaiwut A, Brown LE & Reilly GC (2007) Collagen and osteopontin upregulation by mechanical loading of bone cells in porous 3D scaffolds. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 22 (pp S268-S268)
  • Sittichockechaiwut A, Brown LE & Reilly GC (2007) Osteopontin upregulation in a compression bioreactor using two different scaffolds. TISSUE ENGINEERING, Vol. 13(7) (pp 1740-1740)
  • Clarke DA, Coll C, Drury P, Crawford A & Reilly GC (2007) Polyurethane scaffolds for long term mechanical loading in musculoskeletal tissue engineering. TISSUE ENGINEERING, Vol. 13(7) (pp 1743-1743)
  • Sittichokechaiwut A, Clarke DA & Reilly GC (2006) Mechanical stimulation of osteoblastic cells in a 3 dimensional polyurethane foam scaffold.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 21 (pp S373-S373)
  • Sittichokechaiwut A, Ryan AJ & Reilly G (2006) A 3-dimensional, in vitro model to study the effects of compressive loading on osteoblastic cells. European Cells and Materials, Vol. 11(SUPPL.2) (pp 84)
  • Jacobs C, You J, Reilly G, Batra N, Li Y, Malone A, Themiyasathit S, Tang J, Stearns T & Anderson C (2006) Cellular mechanotransduction in Bone: Moving towards a molecular mechanism. European Cells and Materials, Vol. 11(SUPPL.2) (pp 8)
  • Williams S, Reilly G, Sittichokechaiwut A, Clarke DA, Nickel T & Mejia L (2006) . Mcb Molecular and Cellular Biomechanics, Vol. 3(4) (pp 137-138)
  • Notomi T, Ludwig A, Reilly G, Hofmann FB & Skerry TM (2005) HCN2 ion channels regulate bone development, mass and strength.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 20(9) (pp S62-S62)
  • Yao J, Radin S, Reilly G, Leboy PS & Ducheyne P (2005) Solution mediated effect of bioactive glass in poly (lactic-co-glycolic acid)-bioactive glass composites on osteogenesis of marrow stromal cells. BIOCERAMICS 17, Vol. 17 (pp 619-622)
  • Radin S, Reilly G, Bhargave G, Leboy PS & Ducheyne P (2004) Osteogenic effect of bioactive glass on bone marrow cells: Biochemical, chemical and morphological study. Transactions 7th World Biomaterials Congress (pp 200)
  • Reilly GC, Radin S, Bhargave GA, Ducheyne P & Leboy PS (2003) Differential osteogenic effects of 45S bioactive glass on rat and human mesenchymal stem cells.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 18 (pp S346-S346)
  • Jacobs CR, You J, Reilly G, Saunders MM, Kurokouchi K, Yellowley CE & Donahue HJ (2001) An overview of oscialltory fluid flow as a potent loading-induced physical signal in bone cells. American Society of Mechanical Engineers Bioengineering Division Publication BED, Vol. 50 (pp 339-340)
  • REILLY G, KNAPP H, STEMMER A, NIEDERER P & TATE M (2001) Investigation of the morphology of the lacunocanalicular system of cortical bone using atomic force microscopy. Conference on the Mechanical Properties of Cells and Tissues, Vol. 29 (pp 1074-1081)
  • Reilly GC, Haut TR, Yellowley CE, Donahue HJ & Jacobs CR (2001) Manipulation of the glycocalyx of an osteocytic and an osteoblastic cell line does not affect the intracellular calcium increase in response to fluid flow.. J BONE MINER RES, Vol. 16 (pp S481-S481)
  • Reilly GC, Yellowley CE, Donahue HJ & Jacobs CR (2000) Investigation of the signalling pathways involved in the calcium response of bone cells to oscillating fluid flow.. J BONE MINER RES, Vol. 15 (pp S508-S508)
  • Reilly GC & Jacobs CR (2000) Investigation of the glycocalyx of cultured bone cells.. J BONE MINER RES, Vol. 15 (pp S376-S376)
  • Reilly GC, Knapp HF, Stemmer AC, Niederer P & Tate MLK (1999) Using atomic force microscopy to image the lacunocanalicular system of cortical bone.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 14 (pp S553-S553)
  • Reilly GC (1996) Stress-induced damage in bone: Microcracking and other toughening mechanisms. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 11(10) (pp P28-P28)
  • Rigelsford JM, Way L, Gray C, Reilly G & Scutt AM () Using a novel stretching device to study the effects of mechanical strain on tenocytes in-vitro. 3rd international conference on Mechanics of Biomaterials and Tissues. Clearwater Beach, Florida, USA., 2009.

Datasets

  • Marcotti S, Lacroix D & Reilly G .
  • Marcotti S, Lacroix D & Reilly G .
  • Marcotti S, Lacroix D & Reilly G .
  • Marcotti S, Lacroix D & Reilly G .
  • Dall'Ara E, Oliviero S, Reilly G, Bellantuono I & Owen R .

Other

  • Ascenzi MG & Reilly GC (2011) . Journal of Biomechanics, 44(2), 211-212.

Preprints

  • Ryan CS, Claeyssens F & Reilly G (2025) , Cold Spring Harbor Laboratory.
  • Marcotti S, Reilly GC & Lacroix D (2019) , Cold Spring Harbor Laboratory.
  • Gupta D, Silva M, Radziun K, Martinez D, Hill C, Marshall J, Hearnden V, Puertas-Mejia M & Reilly G (2019) , Preprints.org.
Research group
  • Gifty Tetteh (In vitro bone models for biomaterials testing)
  • Wing Kiu Yeung (Surface coatings for orthopaedic implants)
  • Tom Patterson (PolyHIPE particles for bone tissue engineering).
  • Robert Owen (In vitro bone models for osteoporosis research).
  • Zena Wally (Additive manufacturing of porous metals for dental implants).
  • Dirar Qassim (Serum free culture of progenitor cells for craniofacial repair).
  • Stefania Marcotti (Mechanobiology of the glycocalyx of bone cells).
  • Hossein Bahmaee (Microfluidics for co-culture of bone cells).
  • Liam Boyle (Mechanobiology of the primary cilia of bone cells).
  • Hannah Murray (A* collaboration with Nanyang Technological University, Singapore on angiogenesis of tissue-engineered scaffolds).
  • Leonardo Antonini (sandwich PhD student from Federal University of Rio Grande do Sul, Brazil).
Professional activities and memberships
  • President of the
  • Special visiting researcher (PVE): UFRGS, Brazil
  • Fellow of the Higher Education Academy
  • Alice L Jee Young Investigator Award at the 37th International Sun Valley Workshop on Skeletal Biology
  • Editorial boards of: European Cells and Materials, PLoS ONE, Heliyon and Frontiers in Bioengineering
  • Panel member for Marie Skodowska-Curie Fellowships H2020 programme, Life sciences
  • Member of the American Society of Bone and Mineral Research, Orthopaedic Research Society, Tissue and Cell Engineering Society and Tissue Engineering and Regenerative Medicine International Society
Women in Engineering

We interviewed Gwen for the Faculty of Engineering's Wall of Women when she was a Senior Lecturer in Bioengineering. Here's Gwen's interview:

The Wall of Women profiles were taken over a 4/5 year time period and are a snapshot of what our engineers were doing at that time.