Professor David Grundy

School of Biosciences

Emeritus Professor

D.Grundy@sheffield.ac.uk
+44 114 222 4657

Full contact details

Professor David Grundy
School of Biosciences
E06a
Alfred Denny Building
Western Bank
Sheffield
S10 2TN
Profile

Brief career history

  • 1999-Present: Personal Chair, School of Biosciences, Sheffield
  • 2012-2016: Head of Department
  • 1998-2004: Germany Gästprofessor in the Department of Surgery, University of Tübingen, Germany
  • 1996-1999: Reader, Dept. of Biomedical Science, Sheffield
  • 1990-1996: Senior Lecturer, Dept. of Biomedical Science, Sheffield
  • 1990: Visiting Scientist, University of Hohenheim, Germany
  • 1988: Visiting Scientist, University of Western Australia, Perth
  • 1987-1990: Wellcome Trust Senior Lecturer, Department of Biomedical Science, University of Sheffield
  • 1981: Visiting Scientist, University of Calgary, Canada
  • 1980-1987: Lecturer, Department of Physiology, University of Sheffield
  • 1978-1980: Postdoctoral Research Fellow, Department of Physiology, University of Sheffield
Research interests

Neurogastroenterology – The neural control of gut function

My research is focused on the neural control of gut function. The term "neurogastroenterology" has been coined to describe the field of brain-gut interactions. This field has undergone rapid expansion recently for a number of reasons.

Sensory signals from the bladder and bowel: An age old problem

The aim of our research is to understand the function of sensory nerves innervating the bladder and bowel. Sensory signals are pivotal to reflexes that control bladder and bowel function and also mediate sensations associated with urgency and pain. Sensory signaling is up-regulated as a consequence of inflammation and is manifested as hypersensitivity to distension that persists long after inflammation has resolved.

Bladder and bowel disorders such as overactive bladder syndrome and irritable bowel syndrome are often associated with increased sensory signaling and pain.

These disorders have a profound impact on quality of life and are prevalent in the elderly causing constipation, urgency and incontinence but the underlying mechanisms are poorly understood.

Our lab employs neurobiological techniques to study the transduction of sensory signals generated from within the wall of the gastrointestinal tract and bladder.

Our recent studies have identified changes in ion channels and receptors that determine signal transduction and regulate excitability in the peripheral endings.

Mediators released from the epithelial lining of the bladder and bowel play a role in maintaining aberrant signalling. In aged animals there is a differential effect on sensory signalling with augmented signalling in the bladder and a deficit in signalling in the bowel. Current efforts are to identify the molecular basis of aberrant signalling.

While our approach is largely basic science, a strong clinical element is maintained through collaborations aimed at understanding the basis of sensations that arise in both functional and organic GI disorders.

Publications

Show: Featured publications All publications

Journal articles

  • Li Q, Michel K, Annahazi A, Demir IE, Ceyhan GO, Zeller F, Komorowski L, Stöcker W, Beyak MJ, Grundy D , Farrugia G et al (2016) . Scientific Reports, 6.
  • Yu Y, Daly DM, Adam IJ, Kitsanta P, Hill CJ, Wild J, Shorthouse A, Grundy D & Jiang W (2016) . Neurogastroenterology & Motility, 28(10), 1465-1479.
  • Keating C, Nocchi L, Yu Y & Grundy D (2016) . Journal of Physiology, 594(16), 4549-4564.
  • Daly DM, Nocchi L, Liaskos M, McKay NG, Chapple C & Grundy D (2014) . J Physiol, 592(3), 537-549.
  • Keating C, Pelegrin P, Martínez CM & Grundy D (2011) . J Immunol, 187(3), 1467-1474.
  • Jiang W, Adam IJ, Kitsanta P, Tiernan J, Hill C, Shorthouse A & Grundy D (2011) . Gut, 60(2), 281-282.

All publications

Books

  • (2004) . Blackwell Publishing Ltd.

Journal articles

  • Grundy D, Redgrave J & Tse G (2022) . Practical Neurology, 22(1), 82-84.
  • Uhlig F, Grundy L, Garcia-Caraballo S, Brierley SM, Foster SJ & Grundy D (2020) . iScience, 23(11).
  • Chess-Williams R, Sellers DJ, Brierley SM, Grundy D & Grundy L (2019) . Scientific Reports, 9(1).
  • Konthapakdee N, Grundy L, O'Donnell T, Garcia‐Caraballo S, Brierley SM, Grundy D & Daly DM (2019) . The Journal of Physiology.
  • Yu Y, Villalobos-Hernandez EC, Pradhananga S, Baker CC, Keating C, Grundy D, Lomax AE & Reed DE (2019) . American Journal of Physiology-Gastrointestinal and Liver Physiology, 317(3), G275-G284.
  • De Pascalis R, Parnell WJ, Abrahams ID, Shearer T, Daly DM & Grundy D (2018) . Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 474(2218).
  • Grundy L, Chess-Williams R, Brierley SM, Mills K, Moore KH, Mansfield K, Rose’Meyer R, Sellers D & Grundy D (2018) . American Journal of Physiology-Renal Physiology, 315(4), F1174-F1185.
  • Grundy L, Daly DM, Chapple C, Grundy D & Chess-Williams R (2018) . Scientific Reports, 8(1).
  • Hornsby J, Daly D, Grundy D, Cheng F, Robertson AM, Watton P & Thompson M (2017) . Acta Biomaterialia.
  • Mohammed ZA, Doran C, Grundy D & Nassar MA (2017) . Scientific Reports, 7.
  • Li Q, Michel K, Annahazi A, Demir IE, Ceyhan GO, Zeller F, Komorowski L, Stöcker W, Beyak MJ, Grundy D , Farrugia G et al (2016) . Scientific Reports, 6.
  • Nullens S, Deiteren A, Jiang W, Keating C, Ceuleers H, Francque S, Grundy D, De Man JG & De Winter BY (2016) . Journal of Visualized Experiments(116).
  • Yu Y, Daly DM, Adam IJ, Kitsanta P, Hill CJ, Wild J, Shorthouse A, Grundy D & Jiang W (2016) . Neurogastroenterology & Motility, 28(10), 1465-1479.
  • Keating C, Nocchi L, Yu Y & Grundy D (2016) . Journal of Physiology, 594(16), 4549-4564.
  • Keating C & Grundy D (2016) . Adv Exp Med Biol, 891, 71-74.
  • Vanner SJ, Greenwood-Van Meerveld B, Mawe GM, Shea-Donohue T, Verdu EF, Wood J & Grundy D (2016) . Gastroenterology, 150(6), 1280-1291.
  • Yang J, Zhao J, Chen P, Nakaguchi T, Grundy D & Gregersen H (2016) . American Journal of Physiology-Gastrointestinal and Liver Physiology, 310(6), G376-G386.
  • Grundy D (2015) . Experimental Physiology, 100(7), 755-758.
  • Grundy D (2015) . The Journal of Physiology, 593(12), 2547-2549.
  • Doran C, Chetrit J, Holley MC, Grundy D & Nassar MA (2015) . PLOS ONE, 10(6).
  • Ford AP, Undem BJ, Birder LA, Grundy D, Pijacka W & Paton JFR (2015) . Autonomic Neuroscience, 191, 16-24.
  • Yu Y, Jiang W & Grundy D (2014) Involvement of 5-HT in TRPA1 sensory signaling from the GI tract and influence of ageing. NEUROGASTROENTEROLOGY AND MOTILITY, 26, 27-27.
  • Buhner S, Braak B, Li Q, Kugler EM, Klooker T, Wouters M, Donovan J, Vignali S, Mazzuoli-Weber G, Grundy D , Boeckxstaens G et al (2014) . Exp Physiol, 99(10), 1299-1311.
  • Nocchi L, Daly DM, Chapple C & Grundy D (2014) . Aging Cell, 13(3), 540-550.
  • Keating C, Ewart L, Grundy L, Valentin JP & Grundy D (2014) . Neurogastroenterol Motil, 26(7), 980-989.
  • Daly DM, Nocchi L, Liaskos M, McKay NG, Chapple C & Grundy D (2014) . J Physiol, 592(3), 537-549.
  • Grundy D (2013) . Autonomic Neuroscience, 177(1), 28-28.
  • Daly DM, Nocchi L & Grundy D (2013) . Auton Neurosci, 179(1-2), 1-4.
  • Collins VM, Daly DM, Liaskos M, McKay NG, Sellers D, Chapple C & Grundy D (2013) . BJU Int, 112(7), 1018-1026.
  • Azpiroz F, Feinle-Bisset C, Grundy D & Tack J (2013) . Journal of Gastroenterology, 1-13.
  • Zhi L, Dong L, Kong D, Sun B, Sun Q, Zhang G, Rong W & Grundy D (2013) . Neurogastroenterology and Motility.
  • Keating C, Nocchi L, Yu Y & Grundy D (2012) Ageing and gastrointestinal sensory function: Altered colonic mechanosensory and chemosensory function in the aged mouse. NEUROGASTROENTEROLOGY AND MOTILITY, 24, 74-74.
  • Schemann M, Kugler EM, Buhner S, Eastwood C, Donovan J, Jiang W & Grundy D (2012) . PLoS ONE, 7(12).
  • Jiang W, Nocchi L & Grundy D (2012) Assessing the molecular target for hydrogen sulphide in the mouse small intestine and sensory ganglia. NEUROGASTROENTEROLOGY AND MOTILITY, 24, 81-81.
  • Zhang Y & Grundy D (2012) Altered nutrient sensing in the transient receptor potential vanilloid 1 knockout mouse. NEUROGASTROENTEROLOGY AND MOTILITY, 24, 131-131.
  • Donovan J & Grundy D (2012) Reduced sensory neuron activity in the aged mouse. NEUROGASTROENTEROLOGY AND MOTILITY, 24, 146-146.
  • Keating C, Kean S, Nocchi L & Grundy D (2012) Mechanisms underlying motility in the aged gut: A role for altered serotonin signalling processes. NEUROGASTROENTEROLOGY AND MOTILITY, 24, 150-151.
  • Zhao J, Yang J, Grundy D & Gregersen H (2012) Mechano-sensory properties of hypertrophic intestine following chronic obstruction. NEUROGASTROENTEROLOGY AND MOTILITY, 24, 128-128.
  • Jiang W, Yu Y & Grundy D (2012) TRPA1 activation leads to the murine small mesenteric afferent signaling. NEUROGASTROENTEROLOGY AND MOTILITY, 24, 76-76.
  • Yu Y, Adam I, Kitsanta P, Short-House A, Grundy D & Jiang W (2012) Mast cell and enterochromaffin cell distribution in the aged human bowel. NEUROGASTROENTEROLOGY AND MOTILITY, 24, 143-143.
  • Donovan J & Grundy D (2012) . Neurogastroenterol Motil, 24(10), 956-e465.
  • Donovan J, Chetrit J, Collins VM, Braak B, Wouters MM, Nassar MA, Boeckxstaens GE & Grundy D (2012) . Gastroenterology, 142(5).
  • Daly DM, Collins VM, McKay NG, Sellers DJ, Chapple CR & Grundy D (2012) . European Urology Supplements, 11(1), e374-e374.
  • Daly DM, Collins VM, McKay NG, Sellers DJ, Chapple CR & Grundy D (2012) Botulinum neurotoxin A (BoNT/A) attenuates bladder afferent nerve firing and prevents ATP release from the urothelium. EUROPEAN UROLOGY SUPPLEMENTS, 11(1), E374-E374.
  • Enck P, Klosterhalfen S & Grundy D (2012) . Medical Hypotheses.
  • Donovan J & Grundy D (2012) . Neurogastroenterology and Motility, 24(10), 956-e465.
  • Gregersen H, Jiang W, Grundy D & Liao D (2012) . Experimental Physiology.
  • Wang Y-P, Sun B-Y, Li Q, Dong L, Zhang G-H, Grundy D & Rong W-F (2012) Hyperpolarization-activated cyclic nucleotide-gated cation channel subtypes differentially modulate the excitability of murine small intestinal afferents. World Journal of Gastroenterology, 18(6), 522-531.
  • Liao D, Lu X, Kirkup AJ, Jiang W, Grundy D & Gregersen H (2012) Interdependency of stress relaxation and afferent nerve discharge in rat small intestine. Journal of Biomechanics.
  • Yang J, Zhao J, Jiang W, Nakaguchi T, Kunwald P, Grundy D & Gregersen H (2012) . Am. J. Physiology, 302(9), 1025-1034.
  • Keating CD, Pelegrin P, Martinez CM & Grundy D (2011) . Autonomic Neuroscience, 163(1-2), 61-61.
  • Gooch LJ, Daly DM, Chapple CR & Grundy D (2011) . Autonomic Neuroscience, 163(1-2), 47-48.
  • Grundy D (2011) . Neurogastroenterology & Motility, 23(9), 813-813.
  • Keating C, Pelegrin P, Martínez CM & Grundy D (2011) . J Immunol, 187(3), 1467-1474.
  • Jiang W, Kirkup AJ & Grundy D (2011) . J Physiol, 589(Pt 15), 3867-3882.
  • Daly DM, Collins VM, Chapple CR & Grundy D (2011) . Curr Opin Urol, 21(4), 268-274.
  • Grundy D (2011) . Pain, 152(7), 1443-1444.
  • Donovan J & Grundy D (2011) . Neurogastroenterol Motil, 23(6), 567-e209.
  • Daly DM & Grundy D (2011) THE BLADDER AFFERENT RESPONSE TO STIMULATION OF PROTEASE ACTIVATED RECEPTORS (PARS). EUR UROL SUPPL, 10(2), 304-305.
  • Barki NH, Winchester WJ & Grundy D (2011) THE EFFECT OF TRPM8 AGONISTS ON BLADDER AFFERENT FIRING. EUR UROL SUPPL, 10(2), 259-259.
  • Rong W, Kimura H & Grundy D (2011) . Inflamm Allergy Drug Targets, 10(2), 109-117.
  • Bulmer DC & Grundy D (2011) Achieving translation in models of visceral pain. Current Opinion in Pharmacology.
  • Cremon C, Carini G, Wang B, Vasina V, Cogliandro RF, De Giorgio R, Stanghellini V, Grundy D, Tonini M, De Ponti F , Corinaldesi R et al (2011) Intestinal Serotonin Release, Sensory Neuron Activation, and Abdominal Pain in Irritable Bowel Syndrome. American Journal of Gastroenterology.
  • Lubbers T, de Haan JJ, Hadfoune M, Zabeau L, Tavernier J, Zhang Y, Grundy D, Greve JWM & Buurman WA (2011) Chylomicron formation and glucagon-like peptide 1 receptor are involved in activation of the nutritional anti-inflammatory pathway. Journal of Nutritional Biochemistry.
  • Jiang W, Adam IJ, Kitsanta P, Tiernan J, Hill C, Shorthouse A & Grundy D (2011) . Gut, 60(2), 281-282.
  • Krueger D, Foerster M, Mueller K, Zeller F, Slotta-Huspenina J, Donovan J, Grundy D & Schemann M (2010) . NEUROGASTROENT MOTIL, 22(11), 1224-+.
  • Lubbers T, De Haan J-J, Hadfoune M, Zhang Y, Luyer MD, Grundy D, Buurman WA & Greve JW (2010) . Crit Care Med, 38(10), 1996-2002.
  • Keating C, Martinez C, Surprenant A, Grundy D & Pelegrin P (2010) P2X7 receptor regulates the inflammatory response in Trichinella spiralis infected mice. PURINERG SIGNAL, 6, 134-135.
  • Keating C, Martinez V, Ewart L, Gibbons S, Grundy L, Valentin J-P & Grundy D (2010) . Toxicol Appl Pharmacol, 245(3), 299-309.
  • Blackshaw LA & Grundy D (2010) . AUTON NEUROSCI-BASIC, 153(1-2), 1-2.
  • Daly DM, Chess-Williams R, Chapple C & Grundy D (2010) . Eur Urol, 58(1), 31-32.
  • Daly DM, Chess-Williams R, Chapple C & Grundy D (2010) . Eur Urol, 58(1), 22-28.
  • Grundy D & Brookes SJH (2009) , 697-702.
  • Grundy D, De Giorgio R & Schemann M (2009) , 1077-1082.
  • Liu CY, Mueller MH, Rogler G, Grundy D & Kreis ME (2009) . NEUROGASTROENT MOTIL, 21(12).
  • Mueller MH, Xue B, Glatzle J, Hahn J, Grundy D & Kreis ME (2009) . AM J PHYSIOL-GASTR L, 297(4), G655-G662.
  • Keating C, Martinez V, Valentin JP & Grundy D (2009) . Journal of Pharmacological and Toxicological Methods, 60(2), 230-230.
  • den Bosch JV, Torfs P, De Winter BY, De Man JG, Pelckmans PA, Van Marck E, Grundy D, Van Nassauw L & Timmermans JP (2009) . J CELL MOL MED, 13(9B), 3283-3295.
  • Song XY, Chen BN, Zagorodnyuk VP, Lynn PA, Blackshaw LA, Grundy D, Brunsden AM, Costa M & Brookes SJH (2009) . GASTROENTEROLOGY, 137(1), 274-284.
  • Gakis G, Mueller MH, Hahn J, Glatzle J, Grundy D & Kreis ME (2009) . AUTON NEUROSCI-BASIC, 148(1-2), 63-68.
  • Schemann M & Grundy D (2009) . GUT, 58(6), 744-747.
  • Rong W, Keating C, Sun B, Dong L & Grundy D (2009) . NEUROGASTROENT MOTIL, 21(6).
  • Beyak MJ, Bulmer DCE, Sellers D & Grundy D (2009) . Neurogastroenterol Motil, 21(6), 678-681.
  • Collins VM, Chapple CR, McKay NG, Sellers DJ & Grundy D (2009) . Journal of Urology, 181(4S), 82-83.
  • Gallego D, Clave P, Donovan J, Rahmati R, Grundy D, Jimenez M & Beyak MJ (2008) . NEUROGASTROENT MOTIL, 20(12), 1306-1316.
  • Grundy D (2008) . Exp Physiol, 93(11), 1170-1173.
  • Keating C, Beyak M, Foley S, Singh G, Marsden C, Spiller R & Grundy D (2008) . J Physiol, 586(18), 4517-4530.
  • Grundy D (2008) Serotonergic control of gastrointestinal function. FUND CLIN PHARMACOL, 22, 109-109.
  • Grundy D (2008) 5-HT system in the gut: roles in the regulation of visceral sensitivity and motor functions.. Eur Rev Med Pharmacol Sci, 12 Suppl 1, 63-67.
  • Mueller MH, Glatzle J, Kampitoglou D, Kasparek MS, Grundy D & Kreis ME (2008) . ANN SURG, 247(5), 791-802.
  • Kalia N, Hardcastle J, Keating C, Grasa L, Keating C, Pelegrin P, Bardhan KD & Grundy D (2008) . Gut, 57(1), 41-49.
  • Booth CE, Shaw J, Hicks GA, Kirkup AJ, Winchester W & Grundy D (2008) . Neurogastroenterol Motil, 20(2), 149-158.
  • Keating C, Pelegrin P, Surprenant A & Grundy D (2007) The ATP-gated P2X(7) receptor is required for the generation of jejunal afferent mechano-hypersensitivity in Trichinefla spiralis infected. NEUROGASTROENT MOTIL, 19, 19-19.
  • Jiang W, Bulmer D, Winchester W & Grundy D (2007) Ralfinamide, a novel sodium channel blocker, attenuates excitatory mesenteric afferent responses to acute focal intestinal ischemia in vivo. NEUROGASTROENT MOTIL, 19, 29-30.
  • Grundy D (2007) Mechanisms of gut sensation and pain. NEUROGASTROENT MOTIL, 19, 1-1.
  • Grundy D (2007) Serotonergic mechanisms in the control of gastrointestinal afferent sensitivity. NEUROGASTROENT MOTIL, 19, 6-6.
  • hillsley K, mccaul C, aerssens J, peeters PJ, gijsen H, moechars D, coulie B, grundy D & stead RH (2007) . Neurogastroenterology & Motility, 19(9), 769-777.
  • Daly D, Rong W, Chess-Williams R, Chapple C & Grundy D (2007) . J Physiol, 583(Pt 2), 663-674.
  • Brunsden AM, Brookes SJH, Bardhan KD & Grundy D (2007) . Am J Physiol Gastrointest Liver Physiol, 293(2), G422-G428.
  • Grundy D, McLean P & Stead R (2007) . Neurogastroenterol Motil, 19(7), 607-616.
  • Rong W, Winchester WJ & Grundy D (2007) . J Physiol, 581(Pt 2), 779-786.
  • Liu CY, Mueller MH, Grundy D & Kreis ME (2007) . AM J PHYSIOL-GASTR L, 292(5), G1213-G1220.
  • Aerssens J, Hillsley K, Peeters PJ, de Hoogt R, Stanisz A, Lin J, Van den Wyngaert I, Göhlmann HW, Grundy D, Stead RH & Coulie B (2007) . Gastroenterology, 132(4), 1375-1387.
  • Daly D, Chess-Williams R, Chappie C & Grundy D (2007) . European Urology Supplements, 6(2), 38-38.
  • Daly D, Chess-Williams R, Chappie C & Grundy D (2007) . European Urology Supplements, 6(2), 38-38.
  • Daly D, Chess-Williams R, Chapple C & Grundy D (2007) Is TRPV1 involved in the mechanosensitivity of bladder sensory nerves?. EUR UROL SUPPL, 6(2), 38-38.
  • Daly D, Chess-Williams R, Chapple C & Grundy D (2007) The role of nicotinic receptors in bladder sensation. EUR UROL SUPPL, 6(2), 38-38.
  • Daly D, Chess-Williams R, Chapple C & Grundy D (2007) Endogenously released ach alters bladder sensation in a mechanism involving both nicotinic and muscarinc receptors. EUR UROL SUPPL, 6(2), 39-39.
  • Grundy D & Schemann M (2007) . Curr Opin Gastroenterol, 23(2), 121-126.
  • Barbara G, Wang BX, Stanghellini V, De Giorgio R, Cremon C, Di Nardo G, Trevisani M, Campi B, Geppetti P, Tonini M , Bunnett NW et al (2007) . GASTROENTEROLOGY, 132(1), 26-37.
  • Grundy D (2006) . AUTON NEUROSCI-BASIC, 129(1-2), 1-2.
  • Hillsley K, Lin J-H, Stanisz A, Grundy D, Aerssens J, Peeters PJ, Moechars D, Coulie B & Stead RH (2006) . The Journal of Physiology, 576(1), 257-267.
  • Grundy D (2006) . J Physiol, 575(Pt 1), 1-2.
  • Grundy D (2006) . NEUROGASTROENT MOTIL, 18(5), 339-342.
  • Grundy D (2006) . Auton Neurosci, 125(1-2), 76-80.
  • Grundy D, Al-Chaer ED, Aziz Q, Collins SM, Ke M, Taché Y & Wood JD (2006) . Gastroenterology, 130(5), 1391-1411.
  • Grundy D & Schemann M (2006) . Curr Opin Gastroenterol, 22(2), 102-110.
  • Peeters PJ, Aerssens J, de Hoogt R, Stanisz A, Göhlmann HW, Hillsley K, Meulemans A, Grundy D, Stead RH & Coulie B (2006) . Physiological Genomics, 24(3), 252-263.
  • Beyak MJ, Bulmer DCE, Jiang W, Keating C, Rong W & Grundy D (2006) , 1, 685-725.
  • Muller MH, Liu CY, Glatzle J, Weiser D, Kelber O, Enck P, Grundy D & Kreis ME (2006) . PHYTOMEDICINE, 13, 100-106.
  • Grundy D (2005) . J Pediatr Gastroenterol Nutr, 41 Suppl 1, S7-S9.
  • Wang B, Glatzle J, Mueller MH, Kreis M, Enck P & Grundy D (2005) . Am J Physiol Gastrointest Liver Physiol, 289(2), G254-G260.
  • Grundy D & Schemann M (2005) . Curr Opin Gastroenterol, 21(2), 176-182.
  • Liu CY, Jiang W, Muller MH, Grundy D & Kreis ME (2005) . NEUROGASTROENT MOTIL, 17(1), 89-101.
  • Bulmer DCE, Jiang W, Hicks GA, Davis JB, Winchester WJ & Grundy D (2005) . Neurogastroenterol Motil, 17(1), 102-111.
  • Brookes SJH, Cook IJ, Costa M, De Giorgio R, Dent J, Grundy D, Sanders KM, Schemann M, Shea-Donohue T, Smith TK & Tonini M (2005) . Neurogastroenterology and Motility, 17(SUPPL. 3), 2-3.
  • Costa M, Sanders KM, Schemann M, Smith TK, Cook IJ, De Giorgio R, Dent J, Grundy D, Shea-Donohue T, Tonini M & Brookes SJH (2005) . Neurogastroenterology and Motility, 17(SUPPL. 3), 4-19.
  • Shea-Donohue T, Cook IJ, De Giorgio R, Tonini M, Dent J, Costa M, Grundy D, Sanders KM, Schemann M, Smith TK & Brookes SJH (2005) . Neurogastroenterology and Motility, 17(SUPPL. 3), 20-40.
  • Liu C-Y, Muller MH, Glatzle J, Weiser D, Kelber O, Enck P, Grundy D & Kreis ME (2004) . Neurogastroenterology and Motility, 16(6), 759-764.
  • Rong W, Hillsley K, Davis JB, Hicks G, Winchester WJ & Grundy D (2004) . J Physiol, 560(Pt 3), 867-881.
  • Grundy D & Schemann M (2004) . NEUROGASTROENT MOTIL, 16(5), 507-509.
  • Grundy D, Booth CE, Winchester W & Hicks GA (2004) . Neurogastroenterol Motil, 16 Suppl 2, 29-37.
  • Berthoud HR, Blackshaw LA, Brookes SJH & Grundy D (2004) Neuroanatomy of extrinsic afferents supplying the gastrointestinal tract. NEUROGASTROENT MOTIL, 16, 28-33.
  • Grundy D (2004) . Gut, 53 Suppl 2, ii5-ii8.
  • Kirkup AJ, Jiang W, Bunnett NW & Grundy D (2003) . J Physiol, 552(Pt 2), 589-601.
  • Ward SM, Bayguinov J, Won KJ, Grundy D & Berthoud HR (2003) . J COMP NEUROL, 465(1), 121-135.
  • Kreis ME, Mueller MH, Reber D, Glatzle J, Enck P & Grundy D (2003) . NEUROSCI LETT, 345(3), 187-191.
  • Jiang W, Kirkup AJ, Bunnett N & Grundy D (2003) . Gastroenterology, 124(4), A266-A266.
  • Burdyga G, Lal S, Spiller D, Jiang W, Thompson D, Attwodd S, Saeed S, Grundy D, Varro A, Dimaline R & Dockray GJ (2003) . GASTROENTEROLOGY, 124(1), 129-139.
  • Kreis ME, Jiang W, Kirkup AJ & Grundy D (2002) . AM J PHYSIOL-GASTR L, 283(3), G612-G617.
  • Brunsden AM, Jacob S, Bardhan KD & Grundy D (2002) . Am J Physiol Gastrointest Liver Physiol, 283(3), G656-G665.
  • Grundy D (2002) . Gut, 51 Suppl 1, i2-i5.
  • Grundy D (2002) Towards a reduction of rectal pain?. NEUROGASTROENT MOTIL, 14(3), 217-219.
  • Feinle C, Christen M, Grundy D, Faas H, Meier O, Otto B & Fried M (2002) Effects of duodenal fat, protein or mixed-nutrient infusions on epigastric sensations during sustained gastric distension in healthy humans. NEUROGASTROENT MOTIL, 14(2), 205-213.
  • Abdu F, Hicks GA, Hennig G, Allen JP & Grundy D (2002) . Am J Physiol Gastrointest Liver Physiol, 282(4), G624-G633.
  • (2002) . Neurogastroenterology and Motility, 14(1), 1-1.
  • Lal S, Kirkup AJ, Brunsden AM, Thompson DG & Grundy D (2001) Vagal afferent responses to fatty acids of different chain length in the rat. AM J PHYSIOL-GASTR L, 281(4), G907-G915.
  • Booth CE, Kirkup AJ, Hicks GA, Humphrey PP & Grundy D (2001) . Gastroenterology, 121(2), 358-369.
  • (2001) . Neurogastroenterology and Motility, 13(3), 177-178.
  • Lal S, Kirkup AJ, Brunsden AM, Thompson DG & Grundy D (2001) Vagal afferent responses to fatty acids of different chain length in the anaesthetised rat. J PHYSIOL-LONDON, 533, 60P-61P.
  • Faas H, Feinle C, Enck P, Grundy D & Boesiger P (2001) Modulation of gastric motor activity by a centrally acting stimulus, circular vection, in humans. AM J PHYSIOL-GASTR L, 280(5), G850-G857.
  • Kirkup AJ, Brunsden AM & Grundy D (2001) . Am J Physiol Gastrointest Liver Physiol, 280(5), G787-G794.
  • Booth CE, Kirkup AJ, Hicks GA, Humphrey PPA & Grundy D (2001) . Gastroenterology, 120(5), A710-A710.
  • Kreis ME, Jiang W, Kirkup AJ & Grundy D (2001) . Gastroenterology, 120(5), A535-A535.
  • HICKS G, CLAYTON N, GASKIN P, KIRKUP A, SU X, JOSHI S, FRIEDRICH A, CONNOR H, COX B & GRUNDY D (2001) . Gastroenterology, 120(5), A6-A6.
  • Booth CE, Kirkup AJ, Hicks GA, Humphrey PPA & Grundy D (2001) . Gastroenterology, 120(5), A57-A57.
  • Booth CE, Kirkup AJ, Hicks GA, Humphrey PPA & Grundy D (2001) . Gastroenterology, 120(5), A71-A71.
  • Lal S, Kirkup AJ, Brunsden AM, Thompson DG & Grundy D (2001) . Gastroenterology, 120(5), A676-A676.
  • Lal S, Kirkup AJ, Brunsden AM, Thompson DG & Grundy D (2001) Vagal afferent responses to fatty acids of different chain length. GASTROENTEROLOGY, 120(5), A676-A676.
  • Booth CE, Kirkup AJ, Hicks GA, Humphrey PPA & Grundy D (2001) Stimulus-response characteristics of vagal and non-vagal mesenteric afferents from the rat jejunum.. GASTROENTEROLOGY, 120(5), A710-A710.
  • Abdu F, Hicks GA, Allen JP & Grundy D (2001) Multiple mechanisms contribute to the inhibitory action of somatostatin on intestinal peristalsis in the mouse. GASTROENTEROLOGY, 120(5), A180-A180.
  • Jiang W & Grundy D (2001) Intestinal motor and mesenteric afferent sequelae of ischemia/reperfusion injury in the rat.. GASTROENTEROLOGY, 120(5), A224-A224.
  • Kreis ME, Jiang W, Kirkup AJ & Grundy D (2001) Cosensitivity of primary afferents to histamine and 5-HT supplying the rat jejunum.. GASTROENTEROLOGY, 120(5), A535-A535.
  • Reiche D, Hahn J, Jiang W, Grundy D & Stead RH (2001) 5-HT3 receptor immunoreactivity in human and rat intestines. GASTROENTEROLOGY, 120(5), A170-A170.
  • Jiang W, Kreis M & Grundy D (2001) Effects of IL-1 beta on prostaglandin EP receptor mediated stimulation of jejunal motility and afferent discharge in the rat.. GASTROENTEROLOGY, 120(5), A178-A178.
  • Jiang W, Kirkup AJ, Kreis M & Grundy D (2001) Nicotinic activation of vagal afferent fibres supplying the rat jejunum: "Cross-talk" between the enteric and extrinsic innervation?. GASTROENTEROLOGY, 120(5), A178-A178.
  • Booth CE, Kirkup AJ, Hicks GA, Humphrey PPA & Grundy D (2001) Systemic bacterial lipopolysaccharide elicits acute sensitisation of intestinal afferent nerves to chemical and mechanical stimuli in the rat. GASTROENTEROLOGY, 120(5), A71-A71.
  • Brunsden AM, Jacob S, Bardhan K & Grundy D (2001) Afferent/endothelial interactions may 'sense' flow in the mesenteric vasculature.. GASTROENTEROLOGY, 120(5), A84-A84.
  • Hicks GA, Clayton NM, Gaskin PJ, Kirkup AJ, Su X, Joshi S, Friedrich A, Connor HE, Cox B, Grundy D , Gebhart GF et al (2001) 5-HT4 receptor agonists stimulate small intestinal transit but do not have direct visceral antinociceptive effects in the rat.. GASTROENTEROLOGY, 120(5), A6-A6.
  • Booth CE, Kirkup AJ, Hicks GA, Humphrey PPA & Grundy D (2001) Characterization of the populations of mesenteric afferent nerves inhibited by octreotide in anesthetized rats.. GASTROENTEROLOGY, 120(5), A57-A57.
  • Feinle C, Grundy D & Fried M (2001) Modulation of gastric distension-induced sensations by small intestinal receptors. AM J PHYSIOL-GASTR L, 280(1), G51-G57.
  • Panteleev S & Grundy D (2000) Descending influences from the infralimbic cortex on vago-vagal reflex control of gastric motor activity in the rat. AUTON NEUROSCI-BASIC, 86(1-2), 78-83.
  • Haupt W, Jiang W, Kreis ME & Grundy D (2000) . GASTROENTEROLOGY, 119(6), 1580-1589.
  • Grundy D (2000) . Gut, 47 Suppl 4, iv44-iv45.
  • Eastwood C & Grundy D (2000) . Neurogastroenterol Motil, 12(6), 517-522.
  • Jiang W, Kreis ME, Eastwood C, Kirkup AJ, Humphrey PP & Grundy D (2000) . Gastroenterology, 119(5), 1267-1275.
  • Kreis ME, Muller M, Zittel TT, Glatzle J & Grundy D (2000) Mediators of neuronal activation in the rat brainstem following intestinal anaphylaxis. NEUROSCI LETT, 289(1), 45-48.
  • Kozlowski CM, Bountra C & Grundy D (2000) The effect of fentanyl, DNQX and MK-801 on dorsal horn neurones responsive to colorectal distension in the anaesthetized rat. NEUROGASTROENT MOTIL, 12(3), 239-247.
  • Feinle C, Grundy D, Otto B & Fried M (2000) Relationship between increasing duodenal lipid doses, gastric perception, and plasma hormone levels in humans. AM J PHYSIOL-REG I, 278(5), R1217-R1223.
  • Brunsden AM, Jacob S, Bardhan KD & Grundy D (2000) Sensitivity of mesenteric afferents to vascular perfusion in rat ileum in vitro.. GASTROENTEROLOGY, 118(4), A380-A380.
  • Jiang W, Kirkup AJ, Humphrey PPA & Grundy D (2000) Differential effect of alosetron on mesenteric afferent responses to luminal and systemic antigen in ovalbumin-sensitized rats.. GASTROENTEROLOGY, 118(4), A381-A381.
  • Kirkup AJ, Booth CE, Hicks GA, Humphrey PPA & Grundy D (2000) Effect of alosetron on mechanosensitivity of mesenteric afferent nerve fibres supplying the rat jejunum.. GASTROENTEROLOGY, 118(4), A174-A174.
  • Abdu F, Hicks GA, Allen JP & Grundy D (2000) Characterization of somatostatin receptor mediated inhibition of small intestinal peristalsis in the rat and mouse.. GASTROENTEROLOGY, 118(4), A303-A303.
  • Booth CE, Kirkup AJ, Hicks GA, Humphrey PP & Grundy D (2000) Somatostatin SST2 receptor agonists inhibit bra-dykinin-sensitive jejunal afferents in the rat.. GASTROENTEROLOGY, 118(4), A380-A380.
  • Kirkup AJ, Bunnett NW & Grundy D (2000) A proteinase-activated receptor subtype 2 (PAR-2) agonist stimulates mesenteric afferent nerve discharge.. GASTROENTEROLOGY, 118(4), A173-A173.
  • Kozlowski CM, Green A, Grundy D, Boissonade FM & Bountra C (2000) . Gut, 46(4), 474-480.
  • Grundy D, Schemann M & Wood J (2000) . Neurogastroenterol Motil, 12(2), 105-111.
  • Wingate D & Grundy D (2000) . Neurogastroenterology and Motility, 12(1), 1-1.
  • Jiang W & Grundy D (2000) . J Auton Nerv Syst, 78(2-3), 99-108.
  • Hillsley K, Eeckhout C & Grundy D (2000) . Neurosci Lett, 278(3), 137-140.
  • Booth CE, Kirkup AJ, Hicks GA, Grundy D & Humphrey PPA (2000) Effects of somatostatin on the activity of rat mesenteric afferent nerves in vivo. BRIT J PHARMACOL, 129, U51-U51.
  • Brunsden AM & Grundy D (1999) . J Physiol, 521 Pt 2, 517-527.
  • Kirkup AJ, Booth CE, Chessell IP, Humphrey PP & Grundy D (1999) . J Physiol, 520 Pt 2, 551-563.
  • Hillsley K & Grundy D (1999) . J Auton Nerv Syst, 76(2-3), 93-98.
  • (1999) . Neurogastroenterology & Motility, 11(2), i-ii.
  • Rogers MD, Hardcastle PT, Hardcastle J & Grundy D (1999) Effect of ischemia reperfusion (I/R) on intestinal motility and ion transport: The involvement of histamine. GASTROENTEROLOGY, 116(4), A1071-A1071.
  • Brunsden AM, Kirkup AJ, Panteleev S & Grundy D (1999) Cholecystokinin (CCK) activates autonomic nerves supplying the rat jejunum in vivo.. GASTROENTEROLOGY, 116(4), A966-A966.
  • Jiang W & Grundy D (1999) Role of histamine in the response of jejunal afferents to localized ischemia in the anaesthetized rat. GASTROENTEROLOGY, 116(4), A1012-A1012.
  • Kirkup AJ, Chessell IP, Grundy D & Humphrey PPA (1999) Excitatory effects of ATP on P2X receptors on intestinal afferent nerve endings. GASTROENTEROLOGY, 116(4), A1017-A1017.
  • Feinle C, Christen MC, Meier O, Reichardt B, Grundy D & Fried M (1999) Comparative studies on the effects of duodenal protein, fat or carbohydrate infusions on gastric tone, gastrointestinal sensations and plasma cholecystokinin (CKK) levels in humans. GASTROENTEROLOGY, 116(4), A550-A550.
  • Brasacchio MF, Kirkup AJ, Wagner S, Haupt W, Kreis ME & Grundy D (1999) Mast cell involvement in mesenteric afferent sensitivity of adenosine: 2B or not 2B?. GASTROENTEROLOGY, 116(4), A593-A593.
  • Kirkup AJ, Grundy D, Chessell IP & Humphrey PPA (1999) alpha,beta-methylene-ATP evokes excitation of mesenteric afferent nerves. BRIT J PHARMACOL, 126, U49-U49.
  • Maubach KA & Grundy D (1999) . J Physiol, 515 ( Pt 1), 277-285.
  • Grundy D, Hillsley K, Kirkup AJ & Richards W (1998) Mesenteric afferent sensitivity to cholecystokinin and 5-hydroxytryptamine.. Dtsch Tierarztl Wochenschr, 105(12), 466-468.
  • Kirkup AJ, Eastwood C, Grundy D, Chessell IP & Humphrey PP (1998) . Br J Pharmacol, 125(6), 1352-1360.
  • Hillsley K & Grundy D (1998) . Neurosci Lett, 255(2), 63-66.
  • Eastwood C, Maubach K, Kirkup AJ & Grundy D (1998) . Neurosci Lett, 254(3), 145-148.
  • Kreis ME, Haupt W, Kirkup AJ & Grundy D (1998) Histamine sensitivity of mesenteric afferent nerves in the rat jejunum. AM J PHYSIOL-GASTR L, 38(4), G675-G680.
  • Hillsley K & Grundy D (1998) . J Physiol, 509 ( Pt 3), 717-727.
  • Kreis ME, Haupt W, Kirkup AJ, Becker HD & Grundy D (1998) Novel aspects on histamine sensitivity of intestinal afferent nerve fibers in rat jejunum.. GASTROENTEROLOGY, 114(4), A781-A781.
  • Gooch CL, Boissonade FM & Grundy D (1998) Somatostatin analogue octreotide inhibits retching to cisplatin in anaesthetised ferrets.. GASTROENTEROLOGY, 114(4), A1147-A1147.
  • Jiang W & Grundy D (1998) Differential effects of naproxen on ischemia and reperfusion-induced excitation of jejunal afferents in the anaesthetised rat.. GASTROENTEROLOGY, 114(4), A772-A773.
  • Kirkup AJ, Eastwood C, Chessell IP, Grundy D & Humphrey PPA (1998) Characterization of the receptor mediating the excitatory action of adenosine on mesenteric afferents in the anaesthetised rat.. GASTROENTEROLOGY, 114(4), A778-A778.
  • Feinle C, Grundy D & Fried M (1998) Duodenal lipid causes a dose-dependent change in gastric perception and symptoms but not in gastric tone during distension of the stomach.. GASTROENTEROLOGY, 114(4), A752-A752.
  • Haupt W, Kreis ME, Becker HD & Grundy D (1998) Interleukin-1 beta sensitizes intestinal afferent nerve fibers to other inflammatory mediators in the anesthetized rat.. GASTROENTEROLOGY, 114(4), A762-A762.
  • Rogers MD, Hardcastle J, Hardcastle PT & Grundy D (1998) Sensitization of rat jejunum to 5-hydroxytryptamine after mesenteric ischaemia/reperfusion.. GASTROENTEROLOGY, 114(4), A409-A409.
  • Brunsden A, Maubach K & Grundy D (1998) Visceral afferent sensitisation to bradykinin in rat jejunal in vitro: Putative role for cyclic AMP. GASTROENTEROLOGY, 114(4), A728-A728.
  • Kozlowski CM, Smith EJ, Grundy D & Bountra C (1998) The sodium channel blocker 4030W92 inhibits deoxycholic acid-induced sensitisation of dorsal horn neurone responses to visceral and cutaneous mechanical stimulation in the anaesthetised rat. BRIT J PHARMACOL, 123, U127-U127.
  • Kirkup AJ, Grundy D, Chessell IP & Humphrey PPA (1998) Action of GR79236 on mesenteric afferent discharge in the anaesthetised rat. BRIT J PHARMACOL, 123, U33-U33.
  • Kozlowski CM, Smith EJ, Grundy D & Bountra C (1998) The sodium channel blocker 4030W92 inhibits spinal c-Fos expression in response to somatic and visceral noxious stimulation in the rat. BRIT J PHARMACOL, 123, U126-U126.
  • Sann H, Hoppe S, Baldwin L, Grundy D & Schemann M (1998) Presence of putative neurotransmitters in the myenteric plexus of the gastrointestinal tract and in the musculature of the urinary bladder of the ferret. NEUROGASTROENT MOTIL, 10(1), 35-47.
  • Hillsley K, Kirkup AJ & Grundy D (1998) . J Physiol, 506 ( Pt 2), 551-561.
  • Kirkup AJ & Grundy D (1997) Effects of nifedipine and omega-conotoxin GVIA on 5-hydroxytryptamine-mediated increases in mesenteric afferent discharge in the anaesthetized rat.. J PHYSIOL-LONDON, 504P, P148-P149.
  • Rogers MD, Hardcastle J, Hardcastle PT & Grundy D (1997) The effect of erythromycin on jejunal motility and ion transport in the anaesthetized rat.. J PHYSIOL-LONDON, 504P, P146-P147.
  • Eastwood C, Hillsley K, Kreis M, Maubach K & Grundy D (1997) Inflammatory mediators and the electrophysiology of afferent neurones. GUT, 41, A42-A42.
  • Kirkup AJ, Grundy D, Chessell IP & Humphrey PPA (1997) Characterisation of the receptor mediating the excitatory action of adenosine on mesenteric afferents. BRIT J PHARMACOL, 122, P24-P24.
  • Kozlowski CM, Grundy D & Bountra C (1997) The effect of deoxycholic acid on dorsal horn responses to colorectal distension and cutaneous mechanical stimulation, and the effect of MK-801, in the anaesthetised rat. BRIT J PHARMACOL, 122, P30-P30.
  • Feinle C, Grundy D & Read NW (1997) Effects of duodenal nutrients on sensory and motor responses of the human stomach to distension. AM J PHYSIOL-GASTR L, 36(3), G721-G726.
  • Feinle C, Grundy D & Read NW (1997) . Am J Physiol, 273(3 Pt 1), G721-G726.
  • Kreis ME, Zittel TT, Raybould HE, Reeve JR & Grundy D (1997) Prolonged intestinal afferent nerve discharge in response to cholecystokinin-58 compared to cholecystokinin-8 in rats. NEUROSCI LETT, 230(2), 89-92.
  • Scott CM, Grundy D, Boissonade F & Bountra C (1997) Alosetron inhibits the colorectal distension-evoked depressor response and spinal c-Fos expression in the anaesthetised rat.. GASTROENTEROLOGY, 112(4), A822-A822.
  • Kirkup AJ, Eastwood CD, Grundy D, Chessell IP & Humphrey PPA (1997) Activation of adenosine receptors increases rat mesenteric afferent nerve discharge. BRIT J PHARMACOL, 120, P18-P18.
  • Maubach KA & Grundy D (1997) The role of prostaglandins in the bradykinin-induced activation of serosal afferents of the rat jejunum in vitro. BRIT J PHARMACOL, 120, P78-P78.
  • Kreis ME & Grundy D (1997) Effect of histamine on intestinal afferent nerve discharge in the anaesthetized rat. J PHYSIOL-LONDON, 499P, P102-P103.
  • Eastwood C & Grundy D (1997) Activation of intestinal afferents by endogenous CCK in the proximal jejunum of the anaesthetized rat. J PHYSIOL-LONDON, 499P, P102-P102.
  • Feinle C, Grundy D & Read NW (1997) Effects of duodenal nutrients on sensory and motor responses of the human stomach to distension. American Journal of Physiology, 273(3 PART 1).
  • Richards W, Hillsley K, Eastwood C & Grundy D (1996) . J Physiol, 497 ( Pt 2), 473-481.
  • Eastwood C, Kreis M & Grundy D (1996) Activation of intestinal afferents by Compound 48/80 in the anaesthetized rat: A possible non-mast cell-mediated effect. J PHYSIOL-LONDON, 495P, P99-P100.
  • Baldwin LM, Porter DWF & Grundy D (1996) Enteric reflex control of adaptive relaxation in the ferret stomach in vitro. J PHYSIOL-LONDON, 495P, P104-P104.
  • Grundy D, Enck P & Wood JD (1996) . Neurogastroenterol Motil, 8(2), 153-155.
  • Eastwood C & Grundy D (1996) Mast cell modulation of intestinal afferents.. GASTROENTEROLOGY, 110(4), A659-A659.
  • Grundy D & Hillsley K (1996) . Journal of the Autonomic Nervous System, 58(3), 183-184.
  • Feinle C, Grundy D & Read NW (1995) . Physiol Behav, 58(6), 1159-1165.
  • Grundy D & Schemann M (1995) [Vagovagal regulation of the gastrointestinal tract: from signal conduction to performance response].. Fiziol Zh Im I M Sechenova, 81(11), 104-111.
  • HILLSLEY K & GRUNDY D (1995) CISPLATIN STIMULATES 5-HYDROXYTRYPTAMINE-SENSITIVE MESENTERIC AFFERENTS IN THE JEJUNUM OF THE URETHANE-ANESTHETIZED RAT. J PHYSIOL-LONDON, 487P, P35-P36.
  • FEINLE C, BARBERA R, GRUNDY D & READ NW (1995) THE EFFECTS OF INTRADUODENAL CARBOHYDRATE ON GASTRIC MOTOR AND SENSORY RESPONSES TO GASTRIC DISTENSION. GASTROENTEROLOGY, 108(4), A597-A597.
  • FEINLE C, GRUNDY D & READ NW (1995) EFFECTS OF ISOCALORIC DUODENAL CARBOHYDRATE AND LIPID ON GASTRIC MOTOR AND SENSORY RESPONSES TO GASTRIC DISTENSION. GASTROENTEROLOGY, 108(4), A597-A597.
  • EASTWOOD C & GRUNDY D (1995) MORPHINE STIMULATES INTESTINAL AFFERENT DISCHARGE VIA MU-OPIOID AND DELTA-OPIOID, BUT NOT KAPPA-OPIOID RECEPTORS. GASTROENTEROLOGY, 108(4), A594-A594.
  • GRUNDY D, BAGAEV V & HILLSLEY K (1995) INHIBITION OF GASTRIC MECHANORECEPTOR DISCHARGE BY CHOLECYSTOKININ IN THE RAT. AM J PHYSIOL-GASTR L, 31(2), G355-G360.
  • Grundy D, Bagaev V & Hillsley K (1995) . Am J Physiol, 268(2 Pt 1), G355-G360.
  • Reid K, Grundy D, Khan MI & Read NW (1995) Gastric emptying and the symptoms of vection-induced nausea.. Eur J Gastroenterol Hepatol, 7(2), 103-108.
  • Grundy D & Schemann M (1995) Vagovagal regulation of the gastrointestinal tract: from signal conduction to performance response. Fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk, 81(11), 104-111.
  • Grundy D, Blackshaw LA & Hillsley K (1994) . Dig Dis Sci, 39(12 Suppl), 44S-47S.
  • Grundy D (1994) . Ir J Med Sci, 163(12), 562-564.
  • HILLSLEY K & GRUNDY D (1994) MESENTERIC AFFERENT RESPONSES TO 5-HYDROXYTRYPTAMINE (5-HT) AND CHOLECYSTOKININ (CCK) IN THE ANESTHETIZED RAT. J PHYSIOL-LONDON, 477P, P71-P72.
  • FEINLE C, READ NW, GRUNDY D & KHAN MI (1994) A HIGH-FAT MEAL INCREASES THE SUSCEPTIBILITY TO MOTION SICKNESS IN HEALTHY-SUBJECTS. GASTROENTEROLOGY, 106(4), A1025-A1025.
  • WOOD JD, GRUNDY D & GERSHON MD (1994) LITTLE BRAIN - BIG BRAIN III - SUMMARY REPORT. NEUROGASTROENT MOTIL, 6(1), 1-4.
  • Hillsley K & Grundy D (1994) . Pathophysiology, 1(4), 275.
  • GRUNDY D (1993) THE CHANGING FACE OF GASTROINTESTINAL MOTILITY. J GASTROINTEST MOTIL, 5(4), 231-232.
  • Blackshaw LA & Grundy D (1993) . J Auton Nerv Syst, 45(1), 41-50.
  • Blackshaw LA & Grundy D (1993) . J Auton Nerv Syst, 45(1), 51-59.
  • Grundy D, Gharib-Naseri MK & Hutson D (1993) . Am J Physiol, 265(3 Pt 1), G432-G439.
  • Grundy D, Gharib-Naseri MK & Hutson D (1993) . J Auton Nerv Syst, 43(3), 241-246.
  • Khan MI, Read NW & Grundy D (1993) . Am J Physiol, 264(5 Pt 1), G824-G827.
  • HILLSLEY K & GRUNDY D (1993) MESENTERIC AFFERENT RESPONSES TO 5-HYDROXYTRYPTAMINE (5-HT) RECEPTOR AGONISTS. GASTROENTEROLOGY, 104(4), A1042-A1042.
  • Grundy D (1993) . J Smooth Muscle Res, 29(2), 37-46.
  • GRUNDY D, GHARIBNASERI MK & HUTSON D (1993) CONTRIBUTION OF VAGAL CHOLINERGIC MECHANISMS TO GASTRIC TONE AND MOTILITY IN THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 467, P196-P196.
  • SCHEMANN M & GRUNDY D (1992) ELECTROPHYSIOLOGICAL IDENTIFICATION OF VAGALLY INNERVATED ENTERIC NEURONS IN GUINEA-PIG STOMACH. AM J PHYSIOL, 263(5), G709-G718.
  • Grundy D, Gharib-Naseri MK & Hutson D (1992) . Gut, 33(11), 1473-1476.
  • Hillsley K, Schemann M & Grundy D (1992) . J Auton Nerv Syst, 40(1), 57-62.
  • GRUNDY D, GHARIBNASERI MK & HUTSON D (1992) ROLE OF NITRIC-OXIDE AND VASOACTIVE INTESTINAL POLYPEPTIDE IN VAGALLY MEDIATED RELAXATION OF THE GASTRIC CORPUS IN THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 452, P337-P337.
  • REID K, KHAN MI, READ NW & GRUNDY D (1992) GASTRIC-EMPTYING IN AND SYMPTOMS OF ILLUSORY SELF MOTION. GUT, 33(2), S55-S55.
  • Lindley EJ, Brown BH, Barber DC, Grundy D, Knowles R, McArdle FJ & Wilson AJ (1992) . Clin Phys Physiol Meas, 13 Suppl A, 181-184.
  • Blackshaw LA & Grundy D (1991) . J Auton Nerv Syst, 36(2), 129-137.
  • Grundy D, Reid K, McArdle FJ, Brown BH, Barber DC, Deacon CF & Henderson IW (1991) Trans-thoracic fluid shifts and endocrine responses to 6 degrees head-down tilt.. Aviat Space Environ Med, 62(10), 923-929.
  • Naseri MK, Hutson D & Grundy D (1991) . J Auton Nerv Syst, 36(1), 25-31.
  • BLACKSHAW LA & GRUNDY D (1991) 5-HYDROXYTRYPTAMINE (5-HT3) RECEPTOR-MEDIATED EFFECTS ON VAGAL MUCOSAL AFFERENT-FIBERS FROM THE UPPER GASTROINTESTINAL-TRACT OF THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 435, P64-P64.
  • Lindley EJ, Brown BH, Barber DC, Grundy D, McArdle FJ & Wilson AJ (1991) Monitoring body fluid distribution in microgravity using impedance imaging (APT). Proceedings of the Annual Conference on Engineering in Medicine and Biology, 13(pt 5), 1947-1948.
  • Grundy D, Gharib Naseri MK & Hutson D (1991) Regulation of gastric corpus tone by the vagus nerve in the ferret. Journal of Gastrointestinal Motility, 3(1), 32-38.
  • RICHARDS WJ, READ NW & GRUNDY D (1991) DISCHARGE IN MESENTERIC NERVES FROM THE ILEUM IN RESPONSE TO LUMINAL SHORT CHAIN FATTY-ACIDS IN THE ANESTHETIZED RAT. J PHYSIOL-LONDON, 438, P348-P348.
  • NASERI MKG, HUTSON D & GRUNDY D (1991) VAGAL INFLUENCES ON GASTRIC-ACID SECRETION IN RESPONSE TO GASTRIC DISTENSION IN THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 438, P354-P354.
  • Grundy D & Hansson PA (1991) . Acta Astronaut, 23, 321-325.
  • Blackshaw LA & Grundy D (1990) . J Auton Nerv Syst, 31(3), 191-201.
  • Rudge L, Grundy D, Hutson D, Scratcherd T & Kerrigan D (1990) . Exp Physiol, 75(6), 801-809.
  • GRUNDY D, NASERL MKG & HUTSON D (1990) ROLE OF THE VASOACTIVE INTESTINAL POLYPEPTIDE (VIP) IN THE POSTOPERATIVE SUPPRESSION OF GASTRIC-MOTILITY. GUT, 31(10), A1185-A1185.
  • Sun WM, Read NW, Prior A, Daly JA, Cheah SK & Grundy D (1990) . Gastroenterology, 99(4), 1008-1015.
  • Grundy D (1990) . Exp Physiol, 75(5), 701-708.
  • GRUNDY D (1990) B-AFFERENTS - THE BASIS FOR AUTONOMIC REFLEXES. BEHAV BRAIN SCI, 13(2), 304-304.
  • GRUNDY D, READ NW & RICHARDS WJ (1990) DISCHARGE IN MESENTERIC NERVES FROM THE ILEUM IN RESPONSE TO LUMINAL STIMULI IN THE ANESTHETIZED RAT. J PHYSIOL-LONDON, 424, P14-P14.
  • BLACKSHAW LA & GRUNDY D (1990) REFLEX CHANGES IN GASTROINTESTINAL MOTILITY FOLLOWING CLOSE SYSTEMIC ADMINISTRATION OF CHOLECYSTOKININ-OCTAPEPTIDE IN ANESTHETIZED FERRETS. J PHYSIOL-LONDON, 422, P62-P62.
  • GRUNDY D, KERRIGAN D, RUDGE L & SCRATCHERD T (1990) REFLEX CORPO-ANTRAL COUPLING IN THE CONSCIOUS DOG. J PHYSIOL-LONDON, 422, P61-P61.
  • Grundy D, Hutson D, Rudge LJ & Scratcherd T (1989) . Q J Exp Physiol, 74(6), 857-865.
  • Grundy D & Scratcherd T (1989) Food for thought--nutritional problems in space.. J Br Interplanet Soc, 42(7), 374-377.
  • Grundy D & Scratcherd T (1989) Space: a testbed for basic biomedical sciences.. J Br Interplanet Soc, 42(7), 349-351.
  • Scratcherd T & Grundy D (1989) Physiological problems for man in space.. J Br Interplanet Soc, 42(7), 357-359.
  • Scratcherd T & Grundy D (1989) Calcium metabolism and the osteopenia of space flight.. J Br Interplanet Soc, 42(7), 371-373.
  • Blackshaw LA & Grundy D (1989) . J Auton Nerv Syst, 27(1), 39-45.
  • Blackshaw LA & Grundy D (1988) . Q J Exp Physiol, 73(6), 1001-1004.
  • SCRATCHERD T & GRUNDY D (1988) CONTROL OF GASTRIC PERISTALSIS. GUT, 29(10), A1477-A1477.
  • Grundy D (1988) . J Auton Nerv Syst, 22(3), 175-180.
  • BLACKSHAW LA & GRUNDY D (1988) SPLANCHNO-VAGAL CONVERGENCE ON TO GASTROINTESTINALLY MODULATED VAGAL EFFERENT UNITS IN THE FERRET. J PHYSIOL-LONDON, 396, P35-P35.
  • Grundy D & Read NW (1988) . Baillière's Clinical Gastroenterology, 2(1), ix-ix.
  • Sun WM, Houghton LA, Read NW, Grundy DG & Johnson AG (1988) . Gut, 29(3), 302-305.
  • GRUNDY D (1988) VAGAL CONTROL OF GASTROINTESTINAL FUNCTION. BAILLIERE CLIN GASTR, 2(1), 23-43.
  • GRUNDY D & READ NW (1988) GASTROINTESTINAL NEUROPHYSIOLOGY - FOREWORD. BAILLIERE CLIN GASTR, 2(1), U1-U1.
  • Bull JS, Grundy D & Scratcherd T (1987) . J Physiol, 394, 381-392.
  • SUN WM, HOUGHTON LA, READ NW, GRUNDY D & JOHNSON AG (1987) EFFECT OF MEAL TEMPERATURE ON GASTRIC-EMPTYING OF LIQUIDS IN MAN. GUT, 28(10), A1407-A1408.
  • BLACKSHAW LA & GRUNDY D (1987) THE EFFECTS OF MECHANICAL AND CHEMICAL STIMULI IN THE FERRET STOMACH ON VAGAL EFFERENT UNITARY DISCHARGE. J PHYSIOL-LONDON, 390, P170-P170.
  • BLACKSHAW LA & GRUNDY D (1987) RESPONSES OF VAGAL EFFERENT NEURONS TO INTESTINAL ACIDITY AND OSMOLALITY AS COMPARED TO ANTRAL STIMULI - DIFFERENT MECHANISMS. DIGEST DIS SCI, 32(8), 903-903.
  • BULL JS, GRUNDY D & SCRATCHERD T (1987) PRE-PYLORIC MECHANISMS CONTROLLING GASTRIC-MOTILITY IN THE CONSCIOUS DOG. DIGEST DIS SCI, 32(8), 905-905.
  • BULL JS, GRUNDY D & SCRATCHERD T (1987) MOTOR RESPONSE OF THE CANINE JEJUNUM TO VARIABLE PERIODS OF GASTRIC DISTENSION. J PHYSIOL-LONDON, 386, P60-P60.
  • BLACKSHAW LA, GRUNDY D & SCRATCHERD T (1987) INVOLVEMENT OF GASTROINTESTINAL MECHANORECEPTORS AND INTESTINAL CHEMORECEPTORS IN VAGAL REFLEXES - AN ELECTROPHYSIOLOGICAL STUDY. J AUTONOM NERV SYST, 18(3), 225-234.
  • BLACKSHAW LA, GRUNDY D & SCRATCHERD T (1987) VAGAL AFFERENT DISCHARGE FROM GASTRIC MECHANORECEPTORS DURING CONTRACTION AND RELAXATION OF THE FERRET CORPUS. J AUTONOM NERV SYST, 18(1), 19-24.
  • GRUNDY D, HUTSON D & SCRATCHERD T (1986) A PERMISSIVE ROLE FOR THE VAGUS NERVES IN THE GENESIS OF ANTRO-ANTRAL REFLEXES IN THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 381, 377-384.
  • BLACKSHAW LA, GRUNDY D & SCRATCHERD T (1986) DISCHARGE CHARACTERISTICS OF GASTRIC MECHANORECEPTORS DURING CONTRACTION AND RELAXATION OF THE FERRET CORPUS. J PHYSIOL-LONDON, 378, P19-P19.
  • CLARKE KA, GRUNDY D, SCRATCHERD T & SCRATCHERD TJ (1986) COMPUTER-ASSISTED TEACHING OF PHYSIOLOGY AT SHEFFIELD-UNIVERSITY USING THE ACORN ECONET SYSTEM. J PHYSIOL-LONDON, 378, P6-P6.
  • BLACKSHAW LA, GRUNDY D & SCRATCHERD T (1986) RESPONSES OF VAGAL EFFERENT UNITS MODULATED BY GASTROINTESTINAL STIMULI TO CENTRAL VAGAL-STIMULATION IN THE FERRET. J PHYSIOL-LONDON, 378, P17-P17.
  • SCRATCHERD T, GRUNDY D & COLLMAN PI (1986) EVIDENCE FOR A NONCHOLINERGIC EXCITATORY INNERVATION IN THE CONTROL OF COLONIC MOTILITY. ARCH INT PHARMACOD T, 280(2), 164-175.
  • BULL JS, GRUNDY D & SCRATCHERD T (1985) THE EFFECT OF INTRALUMINAL TRYPTOPHAN AND PHENYLALANINE ON SMALL INTESTINAL MOTILITY IN THE CONSCIOUS DOG. J PHYSIOL-LONDON, 367(OCT), 353-362.
  • GRUNDY D & SCRATCHERD T (1985) THE EFFECT OF SURGICAL ANESTHESIA ON GASTRIC-MOTILITY IN THE FERRET. J PHYSIOL-LONDON, 367(OCT), P56-P56.
  • BLACKSHAW LA, GRUNDY D & SCRATCHERD T (1985) VAGAL EFFERENT RESPONSES TO MECHANICAL AND CHEMICAL-STIMULATION IN THE UPPER GASTROINTESTINAL-TRACT. DIGEST DIS SCI, 30(8), 760-760.
  • BULL JS, GRUNDY D & SCRATCHERD T (1985) JEJUNAL MOTOR RESPONSE TO GASTRIC DISTENSION IN THE DOG. DIGEST DIS SCI, 30(8), 762-762.
  • GRUNDY D, HUTSON D & SCRATCHERD T (1985) PERMISSIVE ROLE FOR THE VAGUS NERVES IN THE GENESIS OF ANTRO-ANTRAL REFLEXES IN THE ANESTHETIZED FERRET. GUT, 26(10), 1108-1109.
  • COLLMAN PI, GRUNDY D, SCRATCHERD T & WACH RA (1984) VAGO-VAGAL REFLEXES TO THE COLON OF THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 352(JUL), 395-402.
  • BULL J, GRUNDY D, SCRATCHERD T & WACH RA (1984) EFFECT OF INTRALUMINAL TRYPTOPHAN AND PHENYLALANINE ON SMALL INTESTINAL MIGRATING MOTOR COMPLEX (MMC) IN THE CONSCIOUS DOG. GUT, 25(11), 1324-1325.
  • COLLMAN PI, GRUNDY D, SCRATCHERD T & WACH RA (1984) VAGO-VAGAL REFLEXES TO THE COLON OF THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 346(JAN), P36-P36.
  • BULL JS, COLLINGE IA, GRUNDY D, SCRATCHERD T & WACH RA (1984) THE EFFECT OF INTRALUMINAL AMINO-ACIDS ON SMALL INTESTINAL MOTILITY IN THE CONSCIOUS DOG. J PHYSIOL-LONDON, 354(SEP), P40-P40.
  • COLLMAN PI, GRUNDY D & SCRATCHERD T (1984) VAGAL CONTROL OF COLONIC MOTILITY IN THE ANESTHETIZED FERRET - EVIDENCE FOR A NON-CHOLINERGIC EXCITATORY INNERVATION. J PHYSIOL-LONDON, 348(MAR), 35-42.
  • SCRATCHERD T & GRUNDY D (1984) THE PHYSIOLOGY OF INTESTINAL MOTILITY AND SECRETION. BRIT J ANAESTH, 56(1), 3-18.
  • BULL JS, GRUNDY D, HUTSON D, LUCKAS M & SCRATCHERD T (1983) THE RESPONSE OF THE PANCREAS OF THE ANESTHETIZED CAT TO SECRETIN BEFORE, DURING AND AFTER VAGAL BLOCKADE. J PHYSIOL-LONDON, 342(SEP), P49-P49.
  • COLLMAN PI, GRUNDY D & SCRATCHERD T (1983) VAGAL AND SPLANCHNIC INFLUENCES ON SMALL INTESTINAL MOTILITY IN THE ANESTHETIZED FERRET. GASTROEN CLIN BIOL, 7(8-9), 720-720.
  • COLLMAN PI, GRUNDY D & SCRATCHERD T (1983) VAGAL INFLUENCES ON THE JEJUNAL MINUTE RHYTHM IN THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 345(DEC), 65-74.
  • GRUNDY D, HUTSON D & SCRATCHERD T (1983) THE RESPONSE OF THE PANCREAS OF THE ANESTHETIZED CAT TO SECRETIN BEFORE, DURING AND AFTER REVERSIBLE VAGAL BLOCKADE. J PHYSIOL-LONDON, 342(SEP), 517-526.
  • GRUNDY D, SCRATCHERD T & SCRATCHERD TJ (1983) COMPUTER-AIDED ANALYSIS OF GASTROINTESTINAL MOTILITY. J PHYSIOL-LONDON, 342(SEP), P4-P4.
  • COLLMAN PI, GRUNDY D & SCRATCHERD T (1982) VAGAL INFLUENCES ON SMALL INTESTINAL MOTILITY IN THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 328(JUL), P51-P52.
  • GRUNDY D & SCRATCHERD T (1982) EFFECT OF STIMULATION OF THE VAGUS NERVE IN BURSTS ON GASTRIC-ACID SECRETION AND MOTILITY IN THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 333(DEC), 451-461.
  • GRUNDY D, ANDREWS PLR & MITCHELL HW (1982) NON-ATROPINIC ANTICHOLINERGIC ACTION OF QUINIDINE ON THE FERRET STOMACH. J AUTON PHARMACOL, 2(1), 21-24.
  • COLLMAN PI, GRUNDY D & SCRATCHERD T (1982) VAGAL INFLUENCES ON LARGE INTESTINAL MOTILITY IN THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 329(AUG), P40-P41.
  • GRUNDY D & DAVISON JS (1981) CARDIOVASCULAR CHANGES ELICITED BY VAGAL GASTRIC AFFERENTS IN THE RAT. Q J EXP PHYSIOL CMS, 66(3), 307-310.
  • ANDREWS PLR & GRUNDY D (1981) THE EFFECT OF STIMULUS CHARACTERISTICS ON THE REBOUND CONTRACTION IN THE GASTRIC CORPUS. J PHYSIOL-LONDON, 313(APR), P24-P25.
  • GRUNDY D, SALIH AA & SCRATCHERD T (1981) MODULATION OF VAGAL EFFERENT FIBER DISCHARGE BY MECHANORECEPTORS IN THE STOMACH, DUODENUM AND COLON OF THE FERRET. J PHYSIOL-LONDON, 319(OCT), 43-52.
  • ANDREWS PLR, GRUNDY D & SCRATCHERD T (1980) VAGAL AFFERENT DISCHARGE FROM MECHANORECEPTORS IN DIFFERENT REGIONS OF THE FERRET STOMACH. J PHYSIOL-LONDON, 298(JAN), 513-524.
  • ANDREWS PLR & GRUNDY D (1980) REBOUND CONTRACTION IN THE STOMACH OF THE ANESTHETIZED FERRET. J PHYSIOL-LONDON, 302(MAY), P9-P10.
  • ANDREWS PLR, GRUNDY D & LAWES INC (1980) THE ROLE OF THE VAGUS AND SPLANCHNIC NERVES IN THE REGULATION OF INTRA-GASTRIC PRESSURE IN THE FERRET. J PHYSIOL-LONDON, 307(OCT), 401-411.
  • ANDREWS PLR, GRUNDY D & SCRATCHERD T (1980) REFLEX EXCITATION OF ANTRAL MOTILITY INDUCED BY GASTRIC DISTENSION IN THE FERRET. J PHYSIOL-LONDON, 298(JAN), 79-84.
  • ANDREWS PLR, FUSSEY IV, GRUNDY D, SALIH AA & SCRATCHERD T (1979) NEURAL ACTIVITY IN THE ABDOMINAL VAGI. GUT, 20(5), A446-A447.
  • ANDREWS PLR, GRUNDY D & SCRATCHERD T (1979) VAGAL AFFERENT DISCHARGE FROM TENSION RECEPTORS IN THE FERRET STOMACH. J PHYSIOL-LONDON, 291(JUN), P33-P33.
  • Davison JS & Grundy D (1978) . The Journal of Physiology, 284(1), 69-82.
  • Davison JS & Grundy D (1978) Distribution of gastrointestinal mechanoreceptors mediating excitation or inhibition of vagal efferent activity in the rat [proceedings]. Journal of Physiology, 280.
  • Davison JS & Grundy D (1977) Modulation of single vagal efferent fibre activity and heart rate by gastric distension in the rat [proceedings]. Journal of Physiology, 269(1).
  • Davison JS & Grundy D (1976) Inhibition of single vagal efferent fibres by gastric distension in the rat [proceedings].. Journal of Physiology, 263(1).
  • Grundy L, Caldwell A, Garcia-Caraballo S, Grundy D, Spencer NJ, Dong X, Castro J, Harrington AM & Brierley SM () . The Journal of Neuroscience.
  • () . Gut, 57(5), 716-716.
  • GRUNDY D () . Neurogastroenterology & Motility, 5(4), 231-232.
  • Grundy D & Wood JD () . Neurogastroenterology & Motility, 4(2), 77-78.
  • Grundy D, Naseri MKG & Hutson D () . Neurogastroenterology & Motility, 3(1), 32-38.
  • Sarna SK, Read NW, Soergel KH & Grundy DG () . Neurogastroenterology & Motility, 1(1), 1-1.

Book chapters

  • Uhlig F & Grundy D (2023) , Visceral Pain (pp. 153-160). Springer International Publishing
  • Brierley SM, Grundy D & Grundy L (2020) , Encyclopedia of Gastroenterology (pp. 701-710). Elsevier
  • Greenwood-Van Meerveld B, Johnson AC & Grundy D (2017) In Greenwood-Van Meerveld B (Ed.), Gastrointestinal Pharmacology. Handbook of Experimental Pharmacology Springer
  • Grundy D, De Giorgio R & Schemann M (2009) , Encyclopedia of Neuroscience: Volumes 1-11 (pp. V3-1077-V3-1082).
  • Grundy D & Brookes SJH (2009) , Encyclopedia of Neuroscience: Volumes 1-11 (pp. V6-697-V6-702).
  • Beyak MJ, Bulmer DCE, Jiang W, Keating C, Rong W & Grundy D (2006) , Physiology of the Gastrointestinal Tract (pp. 685-725). Elsevier
  • Beyak MJ & Grundy D (2005) Vagal afferents innervating the gastrointestinal tract, Advances in Vagal Afferent Neurobiology (pp. 315-350).
  • Jiang W, Hillsley K & Grundy D (2004) , Encyclopedia of Gastroenterology (pp. 339-345). Elsevier
  • Grundy D & Schemann M (2003) Motor control of the stomach, Innervation of the Gastrointestinal Tract (pp. 57-102).
  • Grundy D & Scratcherd T () John Wiley & Sons, Inc.

Conference proceedings

  • Almuhammadi A & Grundy D (2020) Differential effects of oxidative stress on mouse jejunal and colonic mechanosensitive afferent.. NEUROGASTROENTEROLOGY AND MOTILITY, Vol. 32
  • Almuhammadi A & Grundy D (2019) Differential effects of oxidative stress on mouse jejunal and colonic mechanosensitive afferent. NEUROGASTROENTEROLOGY AND MOTILITY, Vol. 31
  • Uhlig F, Grundy L, Castro J, Brierley SM, Foster SJ & Grundy D (2018) Identification of modulators of intestinal nerve activity from Staphylococcus aureus. NEUROGASTROENTEROLOGY AND MOTILITY, Vol. 30
  • Uhlig F, Foster S, Krueger D, Schemann M & Grundy D (2017) Effect of soluble mediators from Staphylococcus aureus on intestinal epithelial function and sensory signaling. NEUROGASTROENTEROLOGY AND MOTILITY, Vol. 29 (pp 128-128)
  • Konthapakdee N, Daly D, Chapple C & Grundy D (2016) ROLE OF 5-HYDROXYTRYPTAMINE IN URINARY BLADDER AFFERENT SIGNALLING. NEUROUROLOGY AND URODYNAMICS, Vol. 35 (pp S66-S67)
  • Grundy L, Mills K, Grundy D & Chess-Williams R (2013) MODULATION OF UROTHELIAL FUNCTION AND AFFERENT SENSITIVITY BY NEUROKININ A.. NEUROUROLOGY AND URODYNAMICS, Vol. 32(6) (pp 637-639)
  • Nocchi L, Daly D, Chapple C & Grundy D (2013) EFFECT OF OXIDATIVE STRESS ON UROTHELIAL-AFFERENT SIGNALLING IN THE MOUSE: POSSIBLE ROLE IN AGED BLADDER DYSFUNCTION. NEUROUROLOGY AND URODYNAMICS, Vol. 32(6) (pp 535-537)
  • Tan S, Daly D, Nocchi L, Chapple C & Grundy D (2013) DEVELOPMENT OF A NEW MODEL FOR STUDYING UROTHELIAL-AFFERENT CROSS-TALK. NEUROUROLOGY AND URODYNAMICS, Vol. 32(6) (pp 537-538)
  • Grundy L, Chess-Williams R & Grundy D (2012) PRIMARY MOUSE UROTHELIAL CELL RESPONSE TO ATP IS MEDIATED BY P2X BUT NOT TRPV1 RECEPTORS. NEUROUROLOGY AND URODYNAMICS, Vol. 31(6) (pp 1021-1022)
  • Barki N, Winchester W & Grundy D (2012) THE EFFECT OF TRPM8 AGONISTS ON BLADDER AFFERENT FIRING. NEUROUROLOGY AND URODYNAMICS, Vol. 31(6) (pp 955-955)
  • Daly D, Nocchi L, Schluter M, McKay N, Keating C, Chapple C & Grundy D (2012) AGED RELATED CHANGES IN PURINERGIC SIGNALLING, AFFERENT FIRING AND RECEPTOR EXPRESSION IN THE MOUSE BLADDER.. NEUROUROLOGY AND URODYNAMICS, Vol. 31(6) (pp 955-956)
  • Grundy L, Daly D, Mansfield K, Chess-Williams R & Grundy D (2012) SENSORY NERVE RESPONSES TO ATP ARE REGULATED BY TRPV1 RECEPTORS.. NEUROUROLOGY AND URODYNAMICS, Vol. 31(6) (pp 794-796)
  • Donovan J, Chetrit J, Collins VM, Braak B, Wouters MM, Nassar MA, Boeckxstaens GE & Grundy D (2012) The Effect of Human Supernatants From IBS Patients on Neuronal Excitability and Sodium Channel Trafficking. GASTROENTEROLOGY, Vol. 142(5) (pp S702-S703)
  • Gooch LJ, Daly DM, Chapple CR & Grundy D (2011) THE ROLE OF THE UROTHELIUM IN POTASSIUM SENSITIVITY TESTING IN THE CLINIC.. NEUROUROLOGY AND URODYNAMICS, Vol. 30(6) (pp 1065-1066)
  • Jiang W & Grundy D (2010) Mast cells are early responders driving mesenteric afferent signaling during intestinal ischemia. NEUROGASTROENTEROLOGY AND MOTILITY, Vol. 22 (pp 31-+)
  • Yang J, Zhao J, Chen P, Nakaguchi T, Grundy D & Gregersen H (2010) Mechano-sensory properties in Goto-Kakizaki rat intestine: a genetic model for type 2 diabetes. NEUROGASTROENTEROLOGY AND MOTILITY, Vol. 22 (pp 56-56)
  • Yang J, Zhao J, Chen P, Nakaguchi T, Grundy D & Gregersen H (2010) Mechano-sensory properties of hypertrophic intestine following chronic obstruction. NEUROGASTROENTEROLOGY AND MOTILITY, Vol. 22 (pp 56-56)
  • Zhang Y, Lubbers T, Buurman WA & Grundy D (2010) Investigating the effect of lipid-containing nutrient on jejunal afferent mechanosensitivity. NEUROGASTROENTEROLOGY AND MOTILITY, Vol. 22 (pp 9-9)
  • Collins VM, Chappie CR, Mc Kay NG, Sellers DJ & Grundy D (2010) . European Urology Supplements, Vol. 9(2) (pp 72-72)
  • Blackshaw LA, Brookes SJH, Grundy D & Schemann M (2007) Sensory transmission in the gastrointestinal tract. NEUROGASTROENTEROLOGY AND MOTILITY, Vol. 19 (pp 1-19)
  • Kalia N, Bardhan KD, Hardcastle J & Grundy D (2005) The effects of bile acids on intestinal ion secretion in the trichinella spiralis infected mouse model of irritable bowel syndrome. GUT, Vol. 54 (pp A78-A79)
  • Hillsley K & Grundy D (2005) Enteric sensory innervation. Functional Disorders of the Gastrointestinal Tract, Vol. 3 (pp 35-41)
  • Brunsden AM, Jacob S, Bardhan KD & Grundy D (2004) Mesenteric afferent sensitivity to vascular perfusion may arise through mechanical distortion. GASTROENTEROLOGY, Vol. 126(4) (pp A160-A160)
  • Kirkup A, Booth C, Stanisz A, Fraser E, Tougas G, Grundy D, Hillsley K & Stead RH (2003) . Gastroenterology, Vol. 124(4) (pp A667-A667)
  • Burdyga G, Lal S, Varro A, Grundy D, Jiang W, Thompson DG, Spiller D, Dimaline R & Dockray GJ (2002) Expression of orexin-1 receptors by rat vagal afferent neurones. JOURNAL OF PHYSIOLOGY-LONDON, Vol. 543 (pp 54P-55P)
  • Brunsden AM, Jacob S, Bardhan KD & Grundy D (2002) Afferent sensitivity to vascular perfusion in rat ileum in vitro: A role for extracellular Ca2+?. GASTROENTEROLOGY, Vol. 122(4) (pp A161-A161)
  • Baker FW, Sanders KM, Grundy D & Ward SM (1999) Compliance of the stomach wall during receptive relaxation is dependent upon interstitial cells of Cajal. Journal of Investigative Medicine, Vol. 47(2)
  • WOOD & GRUNDY (1998) . Neurogastroenterology & Motility, Vol. 10(5) (pp 377-385)
  • GRUNDY D & SCHEMANN M (1994) THE INTERFACE BETWEEN THE ENTERIC AND CENTRAL NERVOUS SYSTEM. INNERVATION OF THE GUT (pp 157-166)

Preprints

  • Grundy L, Caldwell A, Garcia-Caraballo S, Grundy D, Spencer NJ, Dong X, Castro J, Harrington AM & Brierley SM () , Cold Spring Harbor Laboratory.
Grants
  • Marie Curie (EUFP7)
Teaching activities

Undergraduate

  • Level 3 Practical and Dissertation Modules
Professional activities and memberships
  • Chairman of the Management Board of Neurogastroenterology and Motility
  • Member of the Varenna group, an international educational organisation providing teaching material for gastroenterology
  • Executive Board Member & Senior Ethics Editor of the Journal of Physiology
  • Fellow of the American Association of Gastroenterology
  • Member of the Editorial Boards for Gut, Journal of Physiology
  • Autonomic Neuroscience
  • Canadian Journal of Physiology and Pharmacology

Invited seminars

  • ANGMA (Adelaide 2015)
  • British Pharmacological Society (London 2014)
  • Nuffield Council (Sheffield 2014)
  • Australasian Neuroscience Society (Adelaide 2014)