Dr Henry H. Roehl

School of Biosciences

Senior Lecturer

h.roehl@sheffield.ac.uk
+44 114 222 2351
C21, Firth Court

Full contact details

Dr Henry H. Roehl
School of Biosciences
C21
Firth Court
Western Bank
Sheffield
S10 2TN
Profile
  • 2020-2024: Founding Secretary of the International Society for Regenerative Biology
  • 2011-present: Senior Lecturer, University of Sheffield
  • 2002-present: Lecturer, University of Sheffield
  • 1997-2002: Postdoctoral Fellow, Max-Planck-Institut, Tuebingen. Research advisor: Dr. Nuesslein-Volhard
  • 1994-1997: Ph.D. Genetics University of Wisconsin-Madison. Research advisor: Dr. Judith Kimble
  • 1990-1994: Masters Genetics University of Wisconsin-Madison. Research advisor: Dr. Judith Kimble
  • 1983-1988: B.S. Biology, Antioch College
Research interests

The Roehl Laboratory uses zebrafish as a model to study how regeneration takes place in a simple aquatic vertebrate.

Our studies are focused upon addressing the two key questions: where are regenerative cells recruited from, and what are the signals that initiate regeneration. We hope that our results may one day provide information that may enhance clinical approaches to the treatment of injury and disease.

Publications

Show: Featured publications All publications

Journal articles

  • Tomecka MJ, Ethiraj LP, Sánchez LM, Roehl HH & Carney TJ (2019) . Disease Models & Mechanisms, 12(9).
  • Romero MMG, McCathie G, Jankun P & Roehl HH (2018) . Nature Communications, 9.
  • Roehl HH (2018) . International Journal of Developmental Biology, 62(6-8), 473-477.

All publications

Journal articles

  • Tzung K-W, Lalonde RL, Prummel KD, Mahabaleshwar H, Moran HR, Stundl J, Cass AN, Le Y, Lea R, Dorey K , Tomecka MJ et al (2023) . Nature, 618, 543-549.
  • Greaves S, Marsay KS, Monk PN, Roehl H & Partridge LJ (2022) . PLOS ONE, 17(11).
  • Marsay KS, Greaves S, Mahabaleshwar H, Ho CM, Roehl H, Monk PN, Carney TJ & Partridge LJ (2021) . PLoS ONE, 16(11).
  • Tomecka MJ, Ethiraj LP, Sánchez LM, Roehl HH & Carney TJ (2019) . Disease Models & Mechanisms, 12(9).
  • Romero MMG, McCathie G, Jankun P & Roehl HH (2018) . Nature Communications, 9.
  • Roehl HH (2018) . International Journal of Developmental Biology, 62(6-8), 473-477.
  • Felber K, Elks PM, Lecca M & Roehl HH (2015) . PLoS ONE, 10(12).
  • Dyer C, Blanc E, Hanisch A, Roehl H, Otto GW, Yu T, Basson MA & Knight R (2014) . Development, 141(1), 63-72.
  • Gray C, Bratt D, Lees J, daCosta M, Plant K, Watson OJ, Solaymani-Kohal S, Tazzyman S, Serbanovic-Canic J, Crossman DC , Keavney BD et al (2013) . Arterioscler Thromb Vasc Biol, 33(6), 1257-1263.
  • Luo L, Shamsudin S, Twyman L, Cecchin D, Battaglia G, Hua P, Roehl H & Chen B (2012) Delivery systems for small molecule antiprion drug candidates. PRION, 6, 99-99.
  • Wiweger MI, Zhao Z, van Merkesteyn RJP, Roehl HH & Hogendoorn PCW (2012) . Plos One, 7(1).
  • Sousa S, Afonso N, Bensimon-Brito A, Fonseca M, Simões M, Leon J, Roehl H, Cancela ML & Jacinto A (2011) . Development, 138(18), 3897-3905.
  • Trikic MZ, Monk P, Roehl H & Partridge LJ (2011) , 6.
  • Knight RD, Mebus K, d'Angelo A, Yokoya K, Heanue T & Roehl H (2011) . Development, 138(10), 2015-2024.
  • Thompson MJ, Louth JC, Ferrara S, Jackson MP, Sorrell FJ, Cochrane EJ, Gever J, Baxendale S, Silber BM, Roehl HH & Chen B (2011) . Eur J Med Chem, 46(9), 4125-4132.
  • Felber K, Croucher P & Roehl HH (2011) . Mech Dev, 128(1-2), 141-152.
  • Roehl HH & Pacifici M (2010) . Dev Dyn, 239(6), 1901-1904.
  • Li N, Kelsh RN, Croucher P & Roehl HH (2010) . Development, 137(3), 389-394.
  • Knight R, Mebus K & Roehl H (2009) . MECHANISMS OF DEVELOPMENT, 126, S161-S161.
  • Li N, Felber K, Elks P, Croucher P & Roehl HH (2009) . Developmental Dynamics, 238(3).
  • Wiweger M, Roehl H & Hogendoorn PCW (2009) Zebrafish Model for Studies on Bone Defects in Multiple Osteochondromas. MODERN PATHOLOGY, 22, 25A-25A.
  • Wiweger M, Roehl H & Hogendoorn PCW (2009) Zebrafish Model for Studies on Bone Defects in Multiple Osteochondromas. LABORATORY INVESTIGATION, 89, 25A-25A.
  • Li N, Felber K, Elks P, Croucher P & Roehl HH (2009) . Dev Dyn, 238(2), 459-466.
  • Dooley KA, Fraenkel PG, Langer NB, Schmid B, Davidson AJ, Weber G, Chiang K, Foott H, Dwyer C, Wingert RA , Zhou Y et al (2008) . Experimental Hematology, 36(9), 1132-1142.
  • Laue K, Daujat S, Crump JG, Plaster N, Roehl HH, Kimmel CB, Schneider R, Hammerschmidt M & Tuebingen 2000 Screen Consortium (2008) . DEVELOPMENT, 135(11), 1935-1946.
  • Clément A, Wiweger M, von der Hardt S, Rusch MA, Selleck SB, Chien C-B & Roehl HH (2008) . PLoS Genet, 4(7), e1000136.
  • Schorpp M, Bialecki M, Diekhoff D, Walderich B, Odenthal J, Maischein HM, Zapata AG, Boehm T, van Bebber F, Busch-Nentwich E , Dahm R et al (2006) . Journal of Immunology, 177(4), 2463-2476.
  • Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmidt B , Paw BH et al (2005) . Nature, 436(7053), 1035-1039.
  • Jülich D, Chiaw HL, Round J, Nicolaije C, Schroeder J, Davies A, Van Bebber F, Busch-Nentwich E, Dahm R, Frank O , Fronhöfer HG et al (2005) . Developmental Biology, 286(2), 391-404.
  • Jülich D, Geisler R, Holley SA, Van Bebber F, Busch-Nentwich E, Dahm R, Frank O, Fronhöfer HG, Geiger H, Gilmour D , Hooge J et al (2005) . Developmental Cell, 8(4), 575-586.
  • SOLLNER C, RAUCH G, SIEMENS J, GEISLER R, SCHUSTER S, MULLER U, NICOLSON T & CONSORTIUM T (2004) , 428, 955-959.
  • Wingert RA, Brownlie A, Galloway JL, Dooley K, Fraenkel P, Axe JL, Davidson AJ, Barut B, Noriega L, Sheng X , Zhou Y et al (2004) . Development, 131(24), 6225-6235.
  • Busch-Nentwich E, Söllner C, Roehl H & Nicolson T (2004) . Development, 131(4), 943-951.
  • Lee JS, Von Der Hardt S, Rusch MA, Stringer SE, Stickney HL, Talbot WS, Geisler R, Nüsslein-Volhard C, Selleck SB, Chien CB & Roehl H (2004) . Neuron, 44(6), 947-960.
  • Herzog W, Sonntag C, von der Hardt S, Roehl HH, Varga ZM & Hammerschmidt M (2004) . Development, 131(15), 3681-3692.
  • Ulrich F, Concha ML, Heid PJ, Voss E, Witzel S, Roehl H, Tada M, Wilson SW, Adams RJ, Soll DR & Heisenberg CP (2003) . Development, 130(22), 5375-5384.
  • Knaut H, Werz C, Geisler R, Busch-Nentwich E, Dahm R, Frohnhöfer HG, Geiger H, Gilmour D, Holley S, Hooge J , Jülich D et al (2003) . Nature, 421(6920), 279-282.
  • Habeck H, Odenthal J, Walderich B, Maischein HM, Bebber van F, Busch-Nentwich E, Dahm R, Frohnhöfer HG, Geiger H, Gilmour D , Holley S et al (2002) . Current Biology, 12(16), 1405-1412.
  • Roehl H & Nüsslein-Volhard C (2001) . Current Biology, 11(7), 503-507.
  • Geisler R, Rauch G-J, Baier H, van Bebber F, Broβ L, Dekens MPS, Finger K, Fricke C, Gates MA, Geiger H , Geiger-Rudolph S et al (1999) . Nature Genetics, 23(1), 86-89.
  • Panganiban G, Irvine SM, Lowe C, Roehl H, Corley LS, Sherbon B, Grenier JK, Fallon JF, Kimble J, Walker M , Wray GA et al (1997) . Proceedings of the National Academy of Sciences of the United States of America, 94(10), 5162-5166.
  • Roehl H, Bosenberg M, Blelloch R & Kimble J (1996) . EMBO Journal, 15(24), 7002-7012.
  • Roehl H & Kimble J (1993) . Nature, 364(6438), 632-635.
  • Balasubramanian M, Baxendale S & Roehl H () . Bone Abstracts.

Conference proceedings

  • Misra J, Misra J, Mohanty ST, Madan S, Fernandes JA, Ebetino FH, Roehl H, Russell RG & Bellantuono I (2013) Can Bisphosphonates extend Life Span? Effects on Stem Cell survival, DNA Repair and Tissue Regeneration. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 28
  • Felber K, Elks P, Croucher P & Roehl H (2009) . MECHANISMS OF DEVELOPMENT, Vol. 126 (pp S209-S209)
  • Knight RD, Mebus K & Roehl HH (2008) . JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION, Vol. 310B(4) (pp 355-369)
  • Elks PM, Li N, Roehl HH & Croucher PI (2007) WNT signalling upregulates osteoblast differentiation in zebrafish: A novel model for studies in osteoblastogenesis. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 22(7) (pp 1115-1115)

Preprints

  • Greaves S, Marsay KS, Monk PN, Roehl H & Partridge LJ (2021) , Cold Spring Harbor Laboratory.
  • Marsay KS, Greaves S, Mahabaleshwar H, Ho CM, Roehl H, Monk PN, Carney TJ & Partridge LJ (2021) , Cold Spring Harbor Laboratory.
  • Romero MMG, McCathie G, Jankun P & Roehl HH (2018) , Cold Spring Harbor Laboratory.
Research group

PhD studentship opportunities

We advertise PhD opportunities (Funded or Self-Funded) on FindAPhD.com

Grants
  • BBSRC
  • Leverhulme Trust
Teaching activities

Undergraduate

  • BMS11005 - Introductory Developmental, Stem Cell and Regenerative Biology
  • BMS336/6336 - Modelling Human Disease and Dysfunction
  • Level 3 Practical and Dissertation Modules

Links