Dr Gail Maconachie

School of Allied Health, Pharmacy, Nursing and Midwifery

University Lecturer

g.d.maconachie@sheffield.ac.uk
+44 114 225 9034
E100f, 362 Mushroom Lane

Full contact details

Dr Gail Maconachie
School of Allied Health, Pharmacy, Nursing and Midwifery
E100f
362 Mushroom Lane
Sheffield
S10 2TS
Profile

I graduated from the University of Sheffield as an undergraduate with a BMedSci (Orthoptics) in 2009. Following my degree, I took up a post as a research orthoptist at the University of Leicester with an honorary clinical orthoptic contract with the Leicester Royal Infirmary. Alongside this role I under-took a part-time PhD with Professor Irene Gottlob and Dr Frank Proudlock looking at adherence in amblyopia treatment and the development of strabismus. I completed my PhD in 2015 and continued to work as a research orthoptist working within the department with a focus on amblyopia clinical trials and genetics in nystagmus.

In October 2018, I gained a lecturer post at the University of Sheffield. In 2020 I became module lead for our second year undergraduate orthoptic modules and module lead for eye to vision on our distance learning MMedSci Course. I also continue to collaborate with the University of Leicester as an honorary research fellow.

Research interests

My two main research interest areas are ocular genetics and amblyopia treatment.

Publications

Journal articles

  • Hunt C, Yoon H-J, Lirio A, Coley K, Wang J, Shrine N, Shao J, Maconachie GDE, Tu Z, Zippin JH , Hysi PG et al (2025) . Investigative Ophthalmology & Visual Science, 66(12), 22.
  • Sekhri R, Kuht HJ, Tu Z, Maconachie GDE, Shenoy R, Prakash E, Teli S, Rufai SR, Sarvananthan N, Islam T , Hisaund M et al (2025) . Scientific Reports, 15.
  • Sultana M, Davis H, Maconachie G & Codina C (2025) . International Journal for Advancing Practice, 3(2), 71-77.
  • Shenoy R, Maconachie GDE, Parida S, Tu Z, Aamir A, Chean CS, Roked A, Taylor M, Garratt G, Rufai S , Dawar B et al (2025) . Diagnostics, 15(6).
  • Roychaudhury A, Lee Y, Choi T, Thomas MG, Khan TN, Yousaf H, Skinner C, Maconachie G, Crosier M, Horak H , Constantinescu CS et al (2024) . Annals of Neurology, 96(5), 914-931.
  • Proudlock FA, Hisaund M, Maconachie G, Papageorgiou E, Manouchehrinia A, Dahlmann-Noor A, Khandelwal P, Self J, Beisse C, Gottlob I , Mellors A et al (2024) . The Lancet, 403(10438), 1766-1778.
  • Lee H, Purohit R, Sheth V, Maconachie G, Tu Z, Thomas MG, Pilat A, McLean RJ, Proudlock FA & Gottlob I (2023) . American Journal of Ophthalmology, 245, 202-211.
  • Kuht HJ, McLean RJ, Aamir A, Maconachie GDE, Gottlob I & Thomas MG (2023) . Journal of Neuro-Ophthalmology, 43(4), e313-e315.
  • Kuht HJ, Maconachie GDE, Han J, Kessel L, van Genderen MM, McLean RJ, Hisaund M, Tu Z, Hertle RW, Gronskov K , Bai D et al (2022) . Ophthalmology, 129(6), 708-718.
  • Thomas MG, Maconachie GDE, Kuht HJ, Chan W-M, Sheth V, Hisaund M, McLean RJ, Barry B, Al-Diri B, Proudlock FA , Tu Z et al (2021) . International Journal of Molecular Sciences, 22(5).
  • Dawar B, Kuht HJ, Han J, Maconachie GDE & Thomas MG (2021) . European Journal of Human Genetics, 29(10), 1584-1588.
  • Liu S, Kuht HJ, Moon EH, Maconachie GDE & Thomas MG (2021) . Survey of Ophthalmology, 66(2), 362-377.
  • Kuht HJ, Thomas KA, Hisaund M, Maconachie GDE & Thomas MG (2021) . Journal of Neuro-Ophthalmology, 41(3), e293-e296.
  • Kuht HJ, Han J, Maconachie GDE, Park SE, Lee S-T, McLean R, Sheth V, Hisaund M, Dawar B, Sylvius N , Mahmood U et al (2020) . Human Molecular Genetics, 29(18), 2989-3002.
  • Whitman MC, Di Gioia SA, Chan W-M, Gelber A, Pratt BM, Bell JL, Collins TE, Knowles JA, Armoskus C, Pato M , Pato C et al (2020) . Investigative Opthalmology & Visual Science, 61(10), 22-22.
  • Ansell K, Maconachie G & Bjerre A (2020) . British and Irish Orthoptic Journal, 16(1), 19-24.
  • Thomas MG, Maconachie GDE, Constantinescu CS, Chan W-M, Barry B, Hisaund M, Sheth V, Kuht HJ, Dineen RA, Harieaswar S , Engle EC et al (2020) . British Journal of Ophthalmology, 104(4), 547-550.
  • Mayer AK, Mahajnah M, Thomas MG, Cohen Y, Habib A, Schulze M, Maconachie GDE, AlMoallem B, De Baere E, Lorenz B , Traboulsi EI et al (2019) . Brain, 142(6), 1528-1534.
  • Papageorgiou E, Asproudis I, Maconachie G, Tsironi EE & Gottlob I (2019) . Graefe's Archive for Clinical and Experimental Ophthalmology, 257(6), 1061-1078.
  • Shaaban S, MacKinnon S, Andrews C, Staffieri SE, Maconachie GDE, Chan W-M, Whitman MC, Morton SU, Yazar S, MacGregor S , Elder JE et al (2018) . Investigative Opthalmology & Visual Science, 59(10), 4054-4054.
  • Seewoodharry MD, Maconachie GDE, Gillies CL, Gottlob I & McLean RJ (2017) . American Journal of Preventive Medicine, 53(2), 232-240.
  • Thomas MG, Maconachie GDE, Sheth V, McLean RJ & Gottlob I (2017) . European Journal of Human Genetics, 25(6), 725-734.
  • Maconachie GDE, Farooq S, Bush G, Kempton J, Proudlock FA & Gottlob I (2016) . JAMA Ophthalmology, 134(12), 1347-1347.
  • Pilat A, McLean RJ, Proudlock FA, Maconachie GDE, Sheth V, Rajabally YA & Gottlob I (2016) . Investigative Opthalmology & Visual Science, 57(10), 4420-4420.
  • Patel A, Purohit R, Lee H, Sheth V, Maconachie G, Papageorgiou E, McLean RJ, Gottlob I & Proudlock FA (2016) . Ophthalmology, 123(10), 2147-2157.
  • McLean RJ, Maconachie GDE, Gottlob I & Maltby J (2016) . Ophthalmology, 123(9), 2023-2027.
  • Park JG, Tischfield MA, Nugent AA, Cheng L, Di Gioia SA, Chan W-M, Maconachie G, Bosley TM, Summers CG, Hunter DG , Robson CD et al (2016) . The American Journal of Human Genetics, 98(6), 1220-1227.
  • Maconachie GDE & Gottlob I (2015) . Biomedical Journal, 38(6), 510-516.
  • Lee H, Purohit R, Patel A, Papageorgiou E, Sheth V, Maconachie G, Pilat A, McLean RJ, Proudlock FA & Gottlob I (2015) . Investigative Opthalmology & Visual Science, 56(8), 4537-4537.
  • Lee H, Purohit R, Sheth V, Papageorgiou E, Maconachie G, McLean RJ, Patel A, Pilat A, Anwar S, Sarvanathan N , Proudlock FA et al (2015) . The Lancet, 385, S14-S14.
  • Gottlob I, Pilat A, McLean R, Maconachie G, Sheth V, Rajabally Y & Proudlock F (2014) . Neurology, 82(10_supplement).
  • Thomas MG, Crosier M, Lindsay S, Kumar A, Araki M, Leroy BP, McLean RJ, Sheth V, Maconachie G, Thomas S , Moore AT et al (2014) . Human Molecular Genetics, 23(15), 4086-4093.
  • Lee H, Sheth V, Bibi M, Maconachie G, Patel A, McLean RJ, Michaelides M, Thomas MG, Proudlock FA & Gottlob I (2013) . Ophthalmology, 120(12), 2714-2724.
  • Gottlob I, Pilat A, McLean R, Sheth V, Maconachie G, Rajabally Y & Proudlock FA (2013) . Journal of the Neurological Sciences, 333, e134-e135.
  • Maconachie GDE, Gottlob I & McLean RJ (2013) . JAMA Ophthalmology, 131(9), 1179-1179.
  • Sheth V, Gottlob I, Mohammad S, McLean RJ, Maconachie GDE, Kumar A, Degg C & Proudlock FA (2013) . Ophthalmology, 120(10), 2082-2090.
  • Thomas MG, Gottlob I, McLean RJ, Maconachie G, Kumar A & Proudlock FA (2011) . Investigative Opthalmology & Visual Science, 52(11), 8156-8156.
  • Griffiths HJ, Maconachie G & Buckley D (2010) The effect of Fresnel prisms on dynamic visual acuity.. British and Irish Orthoptic Journal, 7, 49-53.
  • Thomas MG, Maconachie G, Hisaund M & Gottlob I (1993) FRMD7-Related Infantile Nystagmus.
  • Aamir A, Kuht HJ, McLean RJ, Maconachie GDE, Sheth V, Dawar B, Purohit R, Sylvius N, Hisaund M, Zubcov-Iwantscheff A , Proudlock FA et al () . Scientific Reports, 11(1).

Conference proceedings

  • Hunt C, Yoon H-J, Lirio A, Coley K, Wang J, Shrine N, Shao J, Maconachie GDE, Tu Z, Zippin JH , Hysi PG et al (2025) . Early Career Researcher Paper Presentation (pp A2.3-A3)
  • Rufai S, Hisaund M, McLean RJ, Purohit R, Maconachie G, Sheth V, Lee H, Proudlock FA, Gottlob I & Thomas MG (2025) Prediction of long-term visual outcomes in infantile nystagmus using handheld OCT: a 12-year longitudinal study. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 66(8)
  • Wong B, Maconachie GDE, Tu Z, Han J, Vasudevan P, Gottlob I & Thomas MG (2024) Exploring Variable Penetrance in Females with X-Linked Retinal Disorders. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 65(7)
  • Tu Z, Reddy N, Kuht H, Maconachie GDE, Han J, Kessel L, Jin J, Yoon H-J, Hunt C, Pani P , Purohit RS et al (2024) International Multi -Centre Validation of Unsupervised Domain Adaptation for Precise Discrimination between Normal and Abnormal Retinal Development. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 65(7)
  • Kuht HJ, Nishad G, Wang SS-H, Maconachie G, Sheth V, Tu Z, Hisaund M, McLean RJ, Purohit R, Teli S , Proudlock FA et al (2021) A machine learning solution to predict foveal development and visual prognosis in retinal developmental disorders. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 62(8)
  • Thomas MG, Kuht HJ, Han J, Sheth V, Maconachie G, Hisaund M, McLean RJ, Purohit R, Tu Z, Park SE , Lee S-T et al (2021) Genotypic and phenotypic spectrum of foveal hypoplasia. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 62(8)

Preprints

  • Shenoy R, Samra GS, Sekhri R, Yoon H-J, Teli S, DeSilva I, Tu Z, Maconachie GDE & Thomas MG (2025) , Cold Spring Harbor Laboratory.
  • Hunt C, Yoon H-J, Lirio A, Coley K, Wang J, Shrine N, Shao J, Maconachie GDE, Tu Z, Zippin JH , Hysi PG et al (2025) , Cold Spring Harbor Laboratory.
  • Kim C-H, Lee Y-R, Thomas M, Roychaudhury A, Skinner C, Maconachie G, Crosier M, Horak H, Constantinescu C, Choi T-I , Kyung J-J et al (2023) , Springer Science and Business Media LLC.
Grants
  • Improving the genetic diagnosis in infantile nystagmus - Fight for Sight 2017 co applicant
  • Can feedback increase adherence to patching and spectacle wear in amblyopia - National Eye Research Centre 2013 co-applicant
Teaching interests

Module Lead:

  • ORT210 clinical orthoptics
  • ORT212 Strabismus and Ocular Motility
  • ORT6003 Eye to Vision
Teaching activities

Undergraduate Admission Tutor

Professional activities and memberships
  • Member of the British and Irish Orthoptic Society
  • Registered with the Health Profession Council
  • Honorary Research Fellow at the University of Leicester
  • Co-Lead for the British & Irish Orthoptic Society Early Career Research Orthoptists network